Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 12 Issue: 9, August

Editorial [Hot Topic: The Therapeutic Potential of FOXO Proteins (Guest Editor: Wolfgang Link)]

Volume:12   Issue: 9
Pp: 1232-1234
Wolfgang Link
DOI: 10.2174/138945011796150235
Published on: 01 March, 2012

FOXO1: A Potential Target for Human Diseases

Volume:12   Issue: 9
Pp: 1235-1244
Huarui Lu and Haojie Huang
DOI: 10.2174/138945011796150280
Published on: 01 March, 2012

Targeting FoxO1 for Hypertriglyceridemia

Volume:12   Issue: 9
Pp: 1245-1255
Dae Hyun Kim, Ting Zhang, Steven Ringquist and H. Henry Dong
DOI: 10.2174/138945011796150262
Published on: 01 March, 2012

FOXO and FOXM1 in Cancer: The FOXO-FOXM1 Axis Shapes the Outcome of Cancer Chemotherapy

Volume:12   Issue: 9
Pp: 1256-1266
Miranda S.C. Wilson, Jan J. Brosens, Helma D.C. Schwenen and Eric W.-F. Lam
DOI: 10.2174/138945011796150244
Published on: 01 March, 2012

Regulation and Function of FoxO Transcription Factors in Normal and Cancer Stem Cells: What Have We Learned?

Volume:12   Issue: 9
Pp: 1267-1283
Xin Zhang, Maite Rielland, Safak Yalcin and Saghi Ghaffari
DOI: 10.2174/138945011796150325
Published on: 01 March, 2012

Deciphering the Role of Forkhead Transcription Factors in Cancer Therapy

Volume:12   Issue: 9
Pp: 1284-1290
Jer-Yen Yang and Mien-Chie Hung
DOI: 10.2174/138945011796150299
Published on: 01 March, 2012

FOXO Transcription Factors and their Role in Disorders of the Female Reproductive Tract

Volume:12   Issue: 9
Pp: 1291-1302
Mark Christian, Eric W.-F. Lam, Miranda S.C. Wilson and Jan J. Brosens
DOI: 10.2174/138945011796150253
Published on: 01 March, 2012

Regulation of Foxo-Dependent Transcription by Post-Translational Modifications

Volume:12   Issue: 9
Pp: 1303-1310
Marco Boccitto and Robert G. Kalb
DOI: 10.2174/138945011796150316
Published on: 01 March, 2012

Harnessing the Tumor Suppressor Function of FOXO as an Alternative Therapeutic Approach in Cancer

Volume:12   Issue: 9
Pp: 1311-1321
Amrik Singh, Jessica Plati and Roya Khosravi-Far
DOI: 10.2174/138945011796150271
Published on: 01 March, 2012

The Complex Biology of FOXO

Volume:12   Issue: 9
Pp: 1322-1350
Maria Monsalve and Yolanda Olmos
DOI: 10.2174/138945011796150307
Published on: 01 March, 2012

Dietary Nitrite in Nitric Oxide Biology: A Redox Interplay with Implications for Pathophysiology and Therapeutics

Volume:12   Issue: 9
Pp: 1351-1363
Barbara S. Rocha, Bruno Gago, Cassilda Pereira, Rui M. Barbosa, Silvina Bartesaghi, Jon O. Lundberg, Rafael Radi and Joao Laranjinha
DOI: 10.2174/138945011796150334
Published on: 01 March, 2012

Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD

Volume:12   Issue: 9
Pp: 1364-1371
O. R. Waters and I. C. Lawrance
DOI: 10.2174/138945011796150343
Published on: 01 March, 2012