Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial [Hot Topic: ABC Transporters: Role in Modulation of Drug Pharmacokinetics and in Physiopathology and Therapeutic Perspectives (Guest Editor: Francoise Van Bambeke)] promotion: free to download

Volume:12   Issue: 5
Pp: 598-599
Francoise Van Bambeke
DOI: 10.2174/138945011795378531

Improving Cancer Chemotherapy with Modulators of ABC Drug Transporters

Volume:12   Issue: 5
Pp: 621-630
S. Shukla, S. Ohnuma and S. V. Ambudkar
DOI: 10.2174/138945011795378540

ATP-Binding Cassette Transporters A1 and G1, HDL Metabolism, Cholesterol Efflux, and Inflammation: Important Targets for the Treatment of Atherosclerosis

Volume:12   Issue: 5
Pp: 647-660
Dan Ye, Bart Lammers, Ying Zhao, Illiana Meurs, Theo J.C. Van Berkel and Miranda Van Eck
DOI: 10.2174/138945011795378522

ABCC6 as a Target in Pseudoxanthoma Elasticum

Volume:12   Issue: 5
Pp: 671-682
Andras Varadi, Zalan Szabo, Viola Pomozi, Hugues de Boussac, Krisztina Fulop and Tamas Aranyi
DOI: 10.2174/138945011795378612

ABC Subfamily D Proteins and Very Long Chain Fatty Acid Metabolism as Novel Targets in Adrenoleukodystrophy

Volume:12   Issue: 5
Pp: 694-706
Masashi Morita, Nobuyuki Shimozawa, Yoshinori Kashiwayama, Yasuyuki Suzuki and Tsuneo Imanaka
DOI: 10.2174/138945011795378577

Editorial [Hot Topic: Calcium Regulatory Proteins as Therapeutic Targets (Guest Editor: Livia C. Hool)] promotion: free to download

Volume:12   Issue: 5
Pp: 707-708
Livia C. Hool
DOI: 10.2174/138945011795378513

The Ryanodine Receptor: A Pivotal Ca2+ Regulatory Protein and Potential Therapeutic Drug Target

Volume:12   Issue: 5
Pp: 709-723
Angela F. Dulhunty, Marco G. Casarotto and Nicole A. Beard
DOI: 10.2174/138945011795378595

Properties and Therapeutic Potential of Transient Receptor Potential Channels with Putative Roles in Adversity: Focus on TRPC5, TRPM2 and TRPA1 open access plus

Volume:12   Issue: 5
Pp: 724-736
L. H. Jiang, N. Gamper and D. J. Beech
DOI: 10.2174/138945011795378568

Triple Threat: The Na+/Ca2+ Exchanger in the Pathophysiology of Cardiac Arrhythmia, Ischemia and Heart Failure

Volume:12   Issue: 5
Pp: 737-747
Christian Pott, Lars Eckardt and Joshua I. Goldhaber
DOI: 10.2174/138945011795378559

Targeting Calcium and the Mitochondria in Prevention of Pathology in the Heart

Volume:12   Issue: 5
Pp: 748-760
Helena M. Viola and Livia C. Hool
DOI: 10.2174/138945011795378603