Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial [Hot Topic: Targeted Therapies in Oncology (Guest Editor: Monica M. Mita)] promotion: free to download

Volume:12   Issue: 14
Pp: 1998-2000
Francis J. Giles
DOI: 10.2174/138945011798829375

Heat Shock Proteins: A Potential Anticancer Target

Volume:12   Issue: 14
Pp: 2001-2008
Kamalesh K. Sankhala, Monica M. Mita, Alain C. Mita and Chris H. Takimoto
DOI: 10.2174/138945011798829339

Vascular Disrupting Agents (VDA) in Oncology: Advancing Towards New Therapeutic Paradigms in the Clinic

Volume:12   Issue: 14
Pp: 2009-2015
Matthew A. Spear, Patricia LoRusso, Alain Mita and Monica Mita
DOI: 10.2174/138945011798829366

Blockade of Insulin-Like Growth Factor Type-1 Receptor with Cixutumumab (IMC-A12): A Novel Approach to Treatment for Multiple Cancers

Volume:12   Issue: 14
Pp: 2016-2033
Eric K. Rowinsky, Jonathan D. Schwartz, Naseem Zojwalla, Hagop Youssoufian, Floyd Fox, Philippe Pultar, Ruslan Novosyadlyy, Jan Cosaert and Dale L. Ludwig
DOI: 10.2174/138945011798829401

The Emerging Role of Poly(ADP-Ribose) Polymerase Inhibitors in Cancer Treatment

Volume:12   Issue: 14
Pp: 2034-2044
Shahneen K. Sandhu, Timothy A. Yap and Johann S. de Bono
DOI: 10.2174/138945011798829438

HGF/c-MET Targeted Therapeutics: Novel Strategies for Cancer Medicine

Volume:12   Issue: 14
Pp: 2045-2058
Timothy A. Yap, Shahneen K. Sandhu, Salma M. Alam and Johann S. de Bono
DOI: 10.2174/138945011798829348

The Pim Kinases: New Targets for Drug Development

Volume:12   Issue: 14
Pp: 2059-2066
Ronan Swords, Kevin Kelly, Jennifer Carew, Stefan Nawrocki, Devalingam Mahalingam, John Sarantopoulos, David Bearss and Francis Giles
DOI: 10.2174/138945011798829447

Targeting Aurora Kinases in Cancer Treatment

Volume:12   Issue: 14
Pp: 2067-2078
Kevin R. Kelly, Jeffrey Ecsedy, Devalingam Mahalingam, Steffan T. Nawrocki, Swaminathan Padmanabhan, Francis J. Giles and Jennifer S. Carew
DOI: 10.2174/138945011798829410

Targeting Trail Towards the Clinic

Volume:12   Issue: 14
Pp: 2079-2090
Devalingam Mahalingam, Corina N.A.M. Oldenhuis, Eva Szegezdi, Francis J. Giles, Elisabeth G.E. de Vries, Steven de Jong and Steffan T. Nawrocki
DOI: 10.2174/138945011798829357

The Hedgehog Knows Many Tricks

Volume:12   Issue: 14
Pp: 2091-2095
Glen J. Weiss, Alain C. Mita and Daniel D. Von Hoff
DOI: 10.2174/138945011798829429

Molecular Players at the Intersection of Obesity and Osteoarthritis

Volume:12   Issue: 14
Pp: 2103-2128
M. Luisa Bonet, Nuria Granados and Andreu Palou
DOI: 10.2174/138945011798829393

Novel Targets for Malaria Therapy

Volume:12   Issue: 14
Pp: 2129-2143
Priyanka Prabhu and Vandana Patravale
DOI: 10.2174/138945011798829384