Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial [Hot topic: Putting the Brakes on Breast Cancer: Therapeutic Opportunities to Bring Cancer Stem Cells and the Tumor Microenvironment to a Screeching Halt (Guest Editor: Tracy Vargo-Gogola)] promotion: free to download

Volume:11   Issue: 9
Pp: 1041-1042
Tracy Vargo-Gogola
DOI: 10.2174/138945010792006834

Small Players With Big Roles: MicroRNAs as Targets to Inhibit Breast Cancer Progression

Volume:11   Issue: 9
Pp: 1059-1073
Stephanie B. Greene, Jason I. Herschkowitz and Jeffrey M. Rosen
DOI: 10.2174/138945010792006762

A Wnt-ow of Opportunity: Targeting the Wnt/β-Catenin Pathway in Breast Cancer

Volume:11   Issue: 9
Pp: 1074-1088
Jenifer R. Prosperi and Kathleen H. Goss
DOI: 10.2174/138945010792006780

Inhibiting Breast Cancer Progression by Exploiting TGFβ Signaling

Volume:11   Issue: 9
Pp: 1089-1102
Sarah E. Baxley and Rosa Serra
DOI: 10.2174/138945010792006771

Hedgehog Signaling in the Normal and Neoplastic Mammary Gland

Volume:11   Issue: 9
Pp: 1103-1111
Adriana P. Visbal and Michael T. Lewis
DOI: 10.2174/138945010792006753

Keeping A Breast of Recent Developments in Cancer Metabolism

Volume:11   Issue: 9
Pp: 1112-1120
Calli A. Davison and Zachary T. Schafer
DOI: 10.2174/138945010792006861

Proinflammatory Cytokines in Breast Cancer: Mechanisms of Action and Potential Targets for Therapeutics

Volume:11   Issue: 9
Pp: 1133-1146
Jodi E. Goldberg and Kathryn L. Schwertfeger
DOI: 10.2174/138945010792006799

Targeting the Perpetrator: Breast Cancer Stem Cell Therapeutics

Volume:11   Issue: 9
Pp: 1147-1156
Arindam Pal, Kelli E. Valdez, Martha Z. Carletti and Fariba Behbod
DOI: 10.2174/138945010792006843

The Macrophage Stimulating Protein/Ron Pathway as a Potential Therapeutic Target to Impede Multiple Mechanisms Involved in Breast Cancer Progression open access plus

Volume:11   Issue: 9
Pp: 1157-1168
Kelsi L. Kretschmann, Henok Eyob, Saundra S. Buys and Alana L. Welm
DOI: 10.2174/138945010792006825

Tyrosine Kinase Receptor Transactivation Associated to G Protein-Coupled Receptors

Volume:11   Issue: 9
Pp: 1169-1180
Vanessa Almendro, Susana Garcia-Recio and Pedro Gascon
DOI: 10.2174/138945010792006807

Molecular Targeting of Aberrant Transcription Factors in Leukemia: Strategies for RUNX1/ETO

Volume:11   Issue: 9
Pp: 1181-1191
Christian Wichmann, Manuel Grez and Jorn Lausen
DOI: 10.2174/138945010792006744