Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 11 Issue: 11, November

Editorial [Hot topic: Targets of Potential Radioprotective Drugs (Guest Editors: Martin)]

Volume:11   Issue: 11
Pp: 1351-1351
Martin Hauer-Jensen and K. Sree Kumar
DOI: 10.2174/1389450111009011351
Published on: 01 March, 2012

Modifying Radiation Damage

Volume:11   Issue: 11
Pp: 1352-1365
Kwanghee Kim and William H. McBride
DOI: 10.2174/1389450111009011352
Published on: 01 March, 2012

Novel Strategies to Ameliorate Radiation Injury: A Possible Role for Tetrahydrobiopterin

Volume:11   Issue: 11
Pp: 1366-1374
Maaike Berbee, Qiang Fu, K. Sree Kumar and Martin Hauer-Jensen
DOI: 10.2174/1389450111009011366
Published on: 01 March, 2012

Hematological Targets of Radiation Damage

Volume:11   Issue: 11
Pp: 1375-1385
Shilpa Kulkarni, Sanchita P. Ghosh, Martin Hauer-Jensen and K. Sree Kumar
DOI: 10.2174/1389450111009011375
Published on: 01 March, 2012

Treatment for Radiation-Induced Pulmonary Late Effects: Spoiled for Choice or Looking in the Wrong Direction?

Volume:11   Issue: 11
Pp: 1386-1394
Jacqueline P. Williams, Carl J. Johnston and Jacob N. Finkelstein
DOI: 10.2174/1389450111009011386
Published on: 01 March, 2012

Modulation of the Rho/ROCK Pathway in Heart and Lung after Thorax Irradiation Reveals Targets to Improve Normal Tissue Toxicity

Volume:11   Issue: 11
Pp: 1395-1404
Virginie Monceau, Nadia Pasinetti, Charlotte Schupp, Fred Pouzoulet, Paule Opolon and Marie-Catherine Vozenin
DOI: 10.2174/1389450111009011395
Published on: 01 March, 2012

Potential Targets for Intervention in Radiation-Induced Heart Disease

Volume:11   Issue: 11
Pp: 1405-1412
M. Boerma and M. Hauer-Jensen
DOI: 10.2174/1389450111009011405
Published on: 01 March, 2012

Renin-angiotensin System Blockers and Modulation of Radiation-Induced Brain Injury

Volume:11   Issue: 11
Pp: 1413-1422
M. E. Robbins, W. Zhao, M. A. Garcia-Espinosa and D. I. Diz
DOI: 10.2174/1389450111009011413
Published on: 01 March, 2012

Mitigation of Radiation Injuries via Suppression of the Renin-Angiotensin System: Emphasis on Radiation Nephropathy

Volume:11   Issue: 11
Pp: 1423-1429
E. P. Cohen, B. L. Fish and J. E. Moulder
DOI: 10.2174/1389450111009011423
Published on: 01 March, 2012

Histone Deacetylase Inhibitors: New Promise in the Treatment of Immune and Inflammatory Diseases

Volume:11   Issue: 11
Pp: 1430-1438
Stephen J. Shuttleworth, Sarah G. Bailey and Paul A. Townsend
DOI: 10.2174/1389450111009011430
Published on: 01 March, 2012

Methionine Aminopeptidases as Potential Targets for Treatment of Gastrointestinal Cancers and other Tumors

Volume:11   Issue: 11
Pp: 1439-1457
Jose L. Mauriz, Javier Martin-Renedo, Andres Garcia-Palomo, Maria J. Tunon and Javier Gonzalez-Gallego
DOI: 10.2174/1389450111009011439
Published on: 01 March, 2012

Effects of Cissampelos sympodialis Eichl. and its Alkaloid, Warifteine, in an Experimental Model of Respiratory Allergy to Blomia tropicalis

Volume:11   Issue: 11
Pp: 1458-1467
Ana Tereza Cerqueira-Lima, Neuza Maria Alcantara-Neves, Lain Carlos Pontes de Carvalho, Ryan Santos Costa, Jose Maria Barbosa-Filho, Marcia Piuvezam, Momtchilo Russo, Renato Barboza, Eduardo de Jesus Oliveira, Alexsandro Marinho and Camila Alexandrina Figueiredo
DOI: 10.2174/1389450111009011458
Published on: 01 March, 2012

Involvement of the Toxic AGEs (TAGE)-RAGE System in the Pathogenesis of Diabetic Vascular Complications: A Novel Therapeutic Strategy open access plus

Volume:11   Issue: 11
Pp: 1468-1482
Masayoshi Takeuchi, Jun-ichi Takino and Sho-ichi Yamagishi
DOI: 10.2174/1389450111009011468
Published on: 01 March, 2012