Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial [Hot topic: Central and Peripheral Metabolic Changes in Neurodegenerative Diseases (Guest Editor: Ana Cristina Rego)] promotion: free to download

Volume:11   Issue: 10
Pp: 1192-1192
Ana Cristina Rego
DOI: 10.2174/1389450111007011192

Multiple Defects in Energy Metabolism in Alzheimers Disease

Volume:11   Issue: 10
Pp: 1193-1206
I. L. Ferreira, R. Resende, E. Ferreiro, A. C. Rego and C. F. Pereira
DOI: 10.2174/1389450111007011193

Metabolic Aspects of Prion Diseases: An Overview

Volume:11   Issue: 10
Pp: 1207-1217
Tanja Vranac and Mara Bresjanac
DOI: 10.2174/1389450111007011207

Mitochondrial-Associated Metabolic Changes and Neurodegeneration in Huntingtons Disease - from Clinical Features to the Bench

Volume:11   Issue: 10
Pp: 1218-1236
Tatiana R. Rosenstock, Ana I. Duarte and A. Cristina Rego
DOI: 10.2174/1389450111007011218

Hypothalamic and Neuroendocrine Changes in Huntingtons Disease

Volume:11   Issue: 10
Pp: 1237-1249
Sofia Hult, Kristofer Schultz, Rana Soylu and Asa Petersen
DOI: 10.2174/1389450111007011237

The Role of PGC-1α in the Pathogenesis of Neurodegenerative Disorders

Volume:11   Issue: 10
Pp: 1262-1269
Krisztina Rona-Voros and Patrick Weydt
DOI: 10.2174/1389450111007011262

Sirtuins: Common Targets in Aging and in Neurodegeneration

Volume:11   Issue: 10
Pp: 1270-1280
Rita Machado de Oliveira, Teresa F. Pais and Tiago Fleming Outeiro
DOI: 10.2174/1389450111007011270

Editorial [Targeting Genetic Instability in Cancer Cells (Guest Editor: Francesco Colotta)] promotion: free to download

Volume:11   Issue: 10
Pp: 1293-1295
Francesco Colotta
DOI: 10.2174/1389450111007011293

The Mutator Phenotype in Cancer: Molecular Mechanisms and Targeting Strategies

Volume:11   Issue: 10
Pp: 1296-1303
Marc J. Prindle, Edward J. Fox and Lawrence A. Loeb
DOI: 10.2174/1389450111007011296

Genetic and Epigenetic Heterogeneity in Cancer: The Ultimate Challenge for Drug Therapy

Volume:11   Issue: 10
Pp: 1304-1316
H. H. Heng, G. Liu, J. B. Stevens, S. W. Bremer, K. J. Ye and C. J. Ye
DOI: 10.2174/1389450111007011304

Genetic Instability Influences Drug Response in Cancer Cells

Volume:11   Issue: 10
Pp: 1317-1324
G. Damia and M. D'Incalci
DOI: 10.2174/1389450111007011317

Targeting Synthetic Lethality in DNA Damage Repair Pathways as an Anti-Cancer Strategy

Volume:11   Issue: 10
Pp: 1336-1340
Benjamin J. Moeller, Wadih Arap and Renata Pasqualini
DOI: 10.2174/1389450111007011336

Targeting Karyotypic Complexity and Chromosomal Instability of Cancer Cells

Volume:11   Issue: 10
Pp: 1341-1350
Anna V. Roschke and Ilan R. Kirsch
DOI: 10.2174/1389450111007011341