Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Open Access Articles

The Professional Phagocyte Dictyostelium discoideum as a Model Host for Bacterial Pathogens open Access plus

Volume: 12   Issue: 7
Pp: 942-954
Salvatore Bozzaro and Ludwig Eichinger

Host-Pathogen Interactions Made Transparent with the Zebrafish Model open Access plus

Volume: 12   Issue: 7
Pp: 1000-1017
Annemarie H. Meijer and Herman P. Spaink

Properties and Therapeutic Potential of Transient Receptor Potential Channels with Putative Roles in Adversity: Focus on TRPC5, TRPM2 and TRPA1 open Access plus

Volume: 12   Issue: 5
Pp: 724-736
L. H. Jiang, N. Gamper and D. J. Beech

The Molecular Mechanisms of Glucocorticoids-Mediated Neutrophil Survival open Access plus

Volume: 12   Issue: 4
Pp: 556-562
Arash S. Saffar, Heather Ashdown and Abdelilah S. Gounni

Heme Oxygenase-1 in Tumor Biology and Therapy open Access plus

Volume: 11   Issue: 12
Pp: 1551-1570
Halina Was, Jozef Dulak and Alicja Jozkowicz

Involvement of the Toxic AGEs (TAGE)-RAGE System in the Pathogenesis of Diabetic Vascular Complications: A Novel Therapeutic Strategy open Access plus

Volume: 11   Issue: 11
Pp: 1468-1482
Masayoshi Takeuchi, Jun-ichi Takino and Sho-ichi Yamagishi

The Macrophage Stimulating Protein/Ron Pathway as a Potential Therapeutic Target to Impede Multiple Mechanisms Involved in Breast Cancer Progression open Access plus

Volume: 11   Issue: 9
Pp: 1157-1168
Kelsi L. Kretschmann, Henok Eyob, Saundra S. Buys and Alana L. Welm

MicroRNA-21: From Cancer to Cardiovascular Disease open Access plus

Volume: 11   Issue: 8
Pp: 926-935
Virginija Jazbutyte and Thomas Thum

Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1 open Access plus

Volume: 10   Issue: 12
Pp: 1212-1226
Akanksha Gupta, Mark D. Williams, William L. Macias, Bruce A. Molitoris and Brian W. Grinnell

Inflammatory Systemic Biomarkers in Setting Acute Coronary Syndromes - Effects of the Diurnal Variation open Access plus

Volume: 10   Issue: 10
Pp: 1001-1008
A. Dominguez-Rodriguez, P. Abreu-Gonzalez and J. C. Kaski