Current Drug Targets

Editor-in-Chief

Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
(USA)

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Most Accessed Articles

New Anti-VEGF Drugs in Ophthalmology

Volume: 21   Issue: 12
Pp: 1194-1200
Claudio Campa *
DOI: 10.2174/1389450121666200428101738

Targeting Cancer Stem Cells Pathways for the Effective Treatment of Cancer promotion: free to download

Volume: 21   Issue: 3
Pp: 258-278
Ashish Ranjan Dwivedi, Amandeep Thakur, Vijay Kumar, Ira Skvortsova and Vinod Kumar*
DOI: 10.2174/1389450120666190821160730

N6-methyladenine RNA Modification (m6A): An Emerging Regulator of Metabolic Diseases

Volume: 21   Issue: 11
Pp: 1056-1067
Hui Zhong, Hui-Fang Tang and Yin Kai*
DOI: 10.2174/1389450121666200210125247

TNF-α and IL-6: The Link between Immune and Bone System promotion: free to download

Volume: 21   Issue: 3
Pp: 213-227
Tiantian Wang and Chengqi He*
DOI: 10.2174/1389450120666190821161259

Targeting Autophagic Pathways by Plant Natural Compounds in Cancer Treatment

Volume: 21   Issue: 12
Pp: 1237-1249
Fatemeh Forouzanfar and Seyed Hadi Mousavi*
DOI: 10.2174/1389450121666200504072635

COVID-19 and Renal Diseases: An Update

Volume: 22   Issue: 1
Pp: 52-67
Letícia Bitencourt, Ana Luisa Pedrosa, Stephanie Bruna Camilo Soares de Brito, Ana Cláudia Fontoura Fróes, Sarah Tayná de Carvalho, Giulio Gori Fonseca, Guilherme Costa Ferreira, Pollyanna Faria Fradico and Ana Cristina Simões e Silva*
DOI: 10.2174/1389450121999201013151300

Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell Signaling

Volume: 22   Issue: 2
Pp: 214-240
Shilpi Agrawal, Sanhita Maity, Zeina AlRaawi, Musaab Al-Ameer and Thallapuranam Krishnaswamy Suresh Kumar*
DOI: 10.2174/1389450121999201012201926

A Review on Rheumatoid Arthritis Interventions and Current Developments

Volume: 22   Issue: 4
Pp: 463-483
Nikita Khanna, Anil Kumar* and Sandip V. Pawar*
DOI: 10.2174/1389450121999201125200558

Target Genetic Abnormalities for the Treatment of Colon Cancer and Its Progression to Metastasis

Volume: 22   Issue: 7
Pp: 722-733
Tushar Baviskar, Munira Momin, Jingwen Liu, Bin Guo and Lokesh Bhatt*
DOI: 10.2174/1389450121666201119141015

Artificial Intelligence, Big Data and Machine Learning Approaches in Precision Medicine & Drug Discovery

Volume: 22   Issue: 6
Pp: 631-655
Anuraj Nayarisseri*, Ravina Khandelwal, Poonam Tanwar, Maddala Madhavi, Diksha Sharma, Garima Thakur, Alejandro Speck-Planche and Sanjeev Kumar Singh*
DOI: 10.2174/1389450122999210104205732

Physcion and Physcion 8-O-β-D-glucopyranoside: Natural Anthraquinones with Potential Anticancer Activities

Volume: 22   Issue: 5
Pp: 488-504
Muhammad Adnan, Azhar Rasul*, Ghulam Hussain, Muhammad Ajmal Shah*, Iqra Sarfraz, Bushra Nageen, Ammara Riaz, Rida Khalid, Muhammad Asrar, Zeliha Selamoglu, Şevki Adem and Satyajit D. Sarker
DOI: 10.2174/1389450121999201013154542

Thrombosis in IBD in the Era of JAK Inhibition

Volume: 22   Issue: 1
Pp: 126-136
Virginia Solitano, Gionata Fiorino, Ferdinando D’Amico, Laurent Peyrin-Biroulet and Silvio Danese*
DOI: 10.2174/1389450121666200902164240

Downregulation of Membrane-bound Angiotensin Converting Enzyme 2 (ACE2) Receptor has a Pivotal Role in COVID-19 Immunopathology

Volume: 22   Issue: 3
Pp: 254-281
Cristina Vieira, Lucas Nery, Ludimila Martins, Luiz Jabour, Raphael Dias and Ana Cristina Simões e Silva*
DOI: 10.2174/1389450121666201020154033

Targeting Host Cell Proteases to Prevent SARS-CoV-2 Invasion

Volume: 22   Issue: 2
Pp: 192-201
Upinder Kaur, Sankha Shubhra Chakrabarti*, Bisweswar Ojha, Bhairav Kumar Pathak, Amit Singh, Luciano Saso and Sasanka Chakrabarti
DOI: 10.2174/1389450121666200924113243

Inhibition of Virulence Factors and Biofilm Formation of Acinetobacter Baumannii by Naturally-derived and Synthetic Drugs

Volume: 22   Issue: 7
Pp: 734-759
Nilushi Indika Bamunuarachchi, Fazlurrahman Khan and Young-Mog Kim*
DOI: 10.2174/1389450121666201023122355

Edaravone May Prevent Ferroptosis in ALS

Volume: 21   Issue: 8
Pp: 776-780
Snežana Spasić*, Aleksandra Nikolić-Kokić, Srđan Miletić, Zorana Oreščanin-Dušić, Mihajlo B. Spasić, Duško Blagojević and Zorica Stević
DOI: 10.2174/1389450121666200220123305

Curcumin and its Multi-target Function Against Pain and Inflammation: An Update of Pre-clinical Data

Volume: 22   Issue: 6
Pp: 656-671
Shaikh Jamal Uddin*, Md. Fahim Hasan, Mohasana Afroz, Dipto Kumer Sarker, Razina Rouf, Muhammad Torequl Islam, Jamil A. Shilpi and Mohammad S. Mubarak*
DOI: 10.2174/1389450121666200925150022

TL1A: A New Potential Target in the Treatment of Inflammatory Bowel Disease

Volume: 22   Issue: 7
Pp: 760-769
Federica Furfaro*, Ludovico Alfarone, Daniela Gilardi, Carmen Correale, Mariangela Allocca, Gionata Fiorino, Marjorie Argollo, Alessandra Zilli, Eirini Zacharopoulou, Laura Loy, Giulia Roda and Silvio Danese
DOI: 10.2174/1389450122999210120205607

Biopolymer-based Scaffolds for Tissue Engineering Applications

Volume: 22   Issue: 3
Pp: 282-295
Hitesh Chopra, Sandeep Kumar and Inderbir Singh*
DOI: 10.2174/1389450121999201102140408