Current Clinical Pharmacology

Comparative Effectiveness of Agmatine and Choline Treatment in Rats with Cognitive Impairment Induced by AlCl₃ and Forced Swim Stress open Access plus

Volume: 15   Issue: 3
Pp: 251-264
Hira Rafi*, Fahad Ahmad, Javaria Anis, Ruba Khan, Hamna Rafiq and Muhammad Farhan
DOI:10.2174/1574884714666191016152143

Medication Non-adherence in Patients with Osteoporosis: Implications for Clinical Pharmacists and Osteoporosis Care Providers open Access plus

Volume: 15   Issue: 3
Pp: 243-250
Anan S. Jarab*, Tareq L. Mukattash and Hayat Hilan
DOI:10.2174/1574884715666200116104754

Effects of Probiotics and Prebiotics on Frailty and Ageing: A Narrative Review open Access plus

Volume: 15   Issue: 3
Pp: 183-192
Kulapong Jayanama* and Olga Theou
DOI:10.2174/1574884714666191120124548

Use of Synbiotics for Ulcerative Colitis Treatment open Access plus

Volume: 15   Issue: 3
Pp: 174-182
Marianna Roselli and Alberto Finamore*
DOI:10.2174/1574884715666191226120322

Prevalence and Predictors of Self-Medication Practices in India: A Systematic Literature Review and Meta-Analysis open Access plus

Volume: 15   Issue: 2
Pp: 90-101
Muhammed Rashid, Manik Chhabra*, Ananth Kashyap, Krishna Undela and Sai K. Gudi
DOI:10.2174/1574884714666191122103953

Prenatal Administration of Betamethasone and Neonatal Respiratory Distress Syndrome in Multifetal Pregnancies: A Randomized Controlled Trial open Access plus

Volume: 15   Issue: 2
Pp: 164-169
Fatemeh Abbasalizadeh, Khadijeh Pouya, Raana Zakeri, Rana Asgari-Arbat*, Shamsi Abbasalizadeh and Neda Parnianfard
DOI:10.2174/1574884714666191007154936

First-in-Human Study of the Safety, Tolerability, Pharmacokinetics and - Preliminary Dynamics of Neuroprotectant 2-Iminobiotin in Healthy Subjects open Access plus

Volume: 15   Issue: 2
Pp: 152-163
Ewoud-Jan van Hoogdalem, Cacha M.P.C.D. Peeters-Scholte, Paul W.T.J. Leufkens, Jan Hartstra, Jan J. van Lier and Leo G.J. de Leede*
DOI:10.2174/1574884714666191017111109

Pomegranate Juice does not Affect the Bioavailability of Cyclosporine in Healthy Thai Volunteers open Access plus

Volume: 15   Issue: 2
Pp: 145-151
Wirin Anlamlert and Pakawadee Sermsappasuk*
DOI:10.2174/1574884715666200110153125

Severe Group A and Group B Streptococcus Diseases at a Pediatric ICU: Are they Still Sensitive to the Penicillins? open Access plus

Volume: 15   Issue: 2
Pp: 125-131
Kam L. Hon*, Tai C. Chow, Tsun S. Cheung, Wai T. Lam, Lok T. Hung, King W. So, I.P. Margaret and Su Y. Qian
DOI:10.2174/1574884714666190926124714

Mitochondrial and Oxidative Impacts of Short and Long-term Administration of HAART on HIV Patients open Access plus

Volume: 15   Issue: 2
Pp: 110-124
Joy E. Ikekpeazu, Oliver C. Orji, Ikenna K. Uchendu* and Lawrence U.S. Ezeanyika
DOI:10.2174/1574884714666190905162237

Minocycline Increases in-vitro Cortical Neuronal Cell Survival after Laser Induced Axotomy open Access plus

Volume: 15   Issue: 2
Pp: 105-109
Burak Yulug*, Mehmet Ozansoy, Merve Alokten, Muzaffer B.C. Ozansoy, Seyda Cankaya, Lutfu Hanoglu, Ulkan Kilic and Ertugrul Kilic
DOI:10.2174/1574884714666190226093119

Tenofovir Urine Assay to Monitor Adherence to HIV Pre-exposure Prophylaxis open Access plus

Volume: 15   Issue: 2
Pp: 102-104
Ganesh S. Moorthy*, Linden Lalley-Chareczko, Helen C. Koenig and Athena F. Zuppa
DOI:10.2174/1574884714666191111125348

The Effect of Methylphenidate on Reed Scaling in Benzodiazepine Poisoning: A Prospective Trial open Access plus

Volume: 15   Issue: 1
Pp: 81-88
Masoud Latifi-Pour, Hossein Hassanian-Moghaddam, Helya-Sadat Mortazavi, Shahin Shadnia, Nasim Zamani and Mitra Rahimi*
DOI:10.2174/1574884714666190112153157

Awareness and Perception of Thromboembolism and Thromboprophylaxis among Hospitalized Patients in Jordan open Access plus

Volume: 15   Issue: 1
Pp: 72-80
Anan S. Jarab*, Sayer Al-Azzam, Rawan Badaineh, Tareq L. Mukattash and Razan Bsoul
DOI:10.2174/1574884714666190823162055

Efficacy and Safety Curcuma zadoaria L. to Inactivate the Hydatid Cyst Protoscoleces open Access plus

Volume: 15   Issue: 1
Pp: 64-71
Hossein Mahmoudvand, Mahbobeh Pakravanan, Farnaz Kheirandish, Sareh Jahanbakhsh, Maryam Sepahvand, Massumeh Niazi, Abdolreza Rouientan and Mohammad R. Aflatoonian*
DOI:10.2174/1574884714666190918155147

Investigation of the Roles of New Antiepileptic Drugs and Serum BDNF Levels in Efficacy and Safety Monitoring and Quality of Life: A Clinical Research open Access plus

Volume: 15   Issue: 1
Pp: 49-63
Meral Demir*, Emel O. Akarsu, Hava O. Dede, Nerses Bebek, Sevda O. Yıldız, Betül Baykan and Ahmet G. Akkan
DOI:10.2174/1574884714666190312145409

Cadazolid vs Vancomycin for the Treatment of Clostridioides difficile Infection: Systematic Review with Meta-analysis open Access plus

Volume: 15   Issue: 1
Pp: 4-10
Aziz Muhammad *, Weissman Simcha, Fatima Rawish, Rajani Sabih, Eid Albert and Nawras Ali
DOI:10.2174/1574884714666190802124301

Drug-Induced Peripheral Neuropathy: A Narrative Review open Access plus

Volume: 15   Issue: 1
Pp: 38-48
Mark R. Jones*, Ivan Urits, John Wolf, Devin Corrigan, Luc Colburn, Emily Peterson, Amber Williamson and Omar Viswanath
DOI:10.2174/1574884714666190121154813

A Review of the Role of Statins in Heart Failure Treatment open Access plus

Volume: 15   Issue: 1
Pp: 30-37
Massumeh Niazi, Nasrin Galehdar, Mohammad Jamshidi, Rasool Mohammadi and Alireza Moayyedkazemi*
DOI:10.2174/1574884714666190802125627

Oral and Intra-nasal Administration of Nanoparticles in the Cerebral Ischemia Treatment in Animal Experiments: Considering its Advantages and Disadvantages open Access plus

Volume: 15   Issue: 1
Pp: 20-29
Firoozeh Alavian* and Nasrin Shams
DOI:10.2174/1574884714666190704115345

The New Immunotherapy Combinations in the Treatment of Advanced Non-Small Cell Lung Cancer: Reality and Perspectives open Access plus

Volume: 15   Issue: 1
Pp: 11-19
Danilo Rocco, Luigi D. Gravara and Cesare Gridelli*
DOI:10.2174/1574884714666190809124555

Azithromycin-induced Aphthous Stomatitis: A Case Series open Access plus

Volume: 14   Issue: 3
Pp: 242-246
Ehsan T. Moghadam and Ali Tafazoli*
DOI:10.2174/1574884714666190301153040

Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid-addicted Patients under General Anesthesia open Access plus

Volume: 14   Issue: 3
Pp: 232-241
Farzaneh Mahikhan, Morteza Hashemian, Tania Dehesh, Elham Jafari, Mandana Jafari and Hamid-Reza Rahimi*
DOI:10.2174/1574884714666190131122846

Melatonin Modulates Regulation of NOX2 and NOX4 Following Irradiation in the Lung open Access plus

Volume: 14   Issue: 3
Pp: 224-231
Masoud Najafi, Alireza Shirazi*, Elahe Motevaseli*, Ghazale Geraily, Peyman Amini, Leila Farhadi Tooli and Dheyauldeen Shabeeb
DOI:10.2174/1574884714666190502151733

Concomitant Use of Cotrimoxazole and Atazanavir in HIV-infected Patients: A Therapeutic Drug Monitoring and Pharmacovigilance Based Dual Approach open Access plus

Volume: 14   Issue: 3
Pp: 214-223
Miantezila B. Joe*, Landman Roland, Chouchana Laurent, Lê M. Patrick, Olivier Sawoo, Tona L. Gaston, Eto Bruno, Peytavin Gilles and Pochart Philippe
DOI:10.2174/1574884714666190405160612

Comparison of the Mean Minimum Dose of Bolus Oxytocin for Proper Uterine Contraction during Cesarean Section open Access plus

Volume: 14   Issue: 3
Pp: 208-213
Siavash Beiranvand, Arash Karimi, Sepideh Vahabi* and Arash Amin-Bidokhti
DOI:10.2174/1574884714666190524100214

Science-based Ethnic Bridging in Drug Development; Review of Recent Precedence and Suggested Steps Forward open Access plus

Volume: 14   Issue: 3
Pp: 197-207
Ewoud-Jan van Hoogdalem*, John P. Jones III, John Constant and Meguru Achira
DOI:10.2174/1574884714666190408125206

A Comprehensive Review on the Screening Models for the Pharmacological Assessment of Antiulcer Drugs open Access plus

Volume: 14   Issue: 3
Pp: 175-196
Abhinav P. Mishra *, Ankit Bajpai and Suresh Chandra
DOI:10.2174/1574884714666190312143846

Surotomycin (A Novel Cyclic Lipopeptide) vs. Vancomycin for the Treatment of Clostridioides difficile Infection: A Systematic Review and Meta-analysis open Access plus

Volume: 14   Issue: 3
Pp: 166-174
Aziz Muhammad*, Desai Madhav, Fatima Rawish, Thoguluva C. Viveksandeep, Eid Albert, Jackson Mollie and Sharma Prateek
DOI:10.2174/1574884714666190328162637

Role of Muscarinic Acetylcholine Receptors in Breast Cancer: Design of Metronomic Chemotherapy open Access plus

Volume: 14   Issue: 2
Pp: 91-100
María E. Sales*, Alejandro J. Español, Agustina R. Salem, Paola M. Pulido, Y. Sanchez and Francisco Sanchez
DOI:10.2174/1574884714666181203095437

Multiple Drug Intolerance Syndrome: An Underreported Distinct Clinical Entity open Access plus

Volume: 14   Issue: 2
Pp: 84-90
Sapan K. Behera, Saibal Das, Kavadichanda G. Chengappa, Alphienes S. Xavier and Sandhiya Selvarajan *
DOI:10.2174/1574884713666181112125714

The Ascent of Mineralocorticoid Receptor Antagonists in Diabetic Nephropathy open Access plus

Volume: 14   Issue: 2
Pp: 78-83
Luxitaa Goenka, Raghavan Padmanaban and Melvin George*
DOI:10.2174/1574884713666181116100946

Protective Effect of Selenium-L-methionine on Radiation-induced Acute Pneumonitis and Lung Fibrosis in Rat open Access plus

Volume: 14   Issue: 2
Pp: 157-164
Peyman Amini, Sedighe Kolivand, Hana Saffar, Saeed Rezapoor, Elahe Motevaseli*, Masoud Najafi*, Farzad Nouruzi, Dheyauldeen Shabeeb and Ahmed Eleojo Musa
DOI:10.2174/1574884714666181214101917

The Possibility of Therapeutic Drug Monitoring of the Most Important Interactions in Nursing Homes open Access plus

Volume: 14   Issue: 2
Pp: 152-156
Pernille Schjøtt, Martina Šutovská and Jan Schjøtt*
DOI:10.2174/1574884714666181224144722

The Cytotoxicity and Synergistic Potential of Aspirin and Aspirin Analogues Towards Oesophageal and Colorectal Cancer open Access plus

Volume: 14   Issue: 2
Pp: 141-151
Rajagopal S. Kilari, Asma’u I.J. Bashir, Andreue Devitt, Christopher J. Perry, Stephen T. Safrany and Iain D. Nicholl*
DOI:10.2174/1574884713666181112141151

Rabbit as an Animal Model for Pharmacokinetics Studies of Enteric Capsule Contains Recombinant Human Keratinocyte Growth Factor Loaded Chitosan Nanoparticles open Access plus

Volume: 14   Issue: 2
Pp: 132-140
Palanirajan V. Kumar*, Marwan A. Abdelkarim Maki, Yeong S. Wei, Lee M. Tatt, Manogaran Elumalai, Shiau-Chuen Cheah, Bharathy Raghavan and Abu Bakar Bin A. Majeed
DOI:10.2174/1574884714666181120103907

Comparison of Fentanyl, Remifentanil, Sufentanil and Alfentanil in Combination with Propofol for General Anesthesia: A Systematic Review and Meta-analysis of Randomized Controlled Trials open Access plus

Volume: 14   Issue: 2
Pp: 116-124
Kannan Sridharan* and Gowri Sivaramakrishnan
DOI:10.2174/1567201816666190313160438

Efficacy and Safety of Nilutamide in Patients with Metastatic Prostate Cancer who Underwent Orchiectomy: A Systematic Review and Metaanalysis open Access plus

Volume: 14   Issue: 2
Pp: 108-115
Muhammed Rashid, K. Shamshavali and Manik Chhabra*
DOI:10.2174/1574884714666190112151202

The Added Value of Liquid Antipsychotics: The Case of Quetiapine open Access plus

Volume: 14   Issue: 2
Pp: 101-107
Georgios Papazisis* and Spyridon Siafis
DOI:10.2174/1574884713666181102145236

Pycnogenol Protects against Pentylenetetrazole-Induced Oxidative Stress and Seizures in Mice open Access plus

Volume: 14   Issue: 1
Pp: 68-75
Radha Goel* and Prasoon Saxena
DOI:10.2174/1574884714666181122110317

Role of Nrf2/HO-1 and PI3K/Akt Genes in the Hepatoprotective Effect of Cilostazol open Access plus

Volume: 14   Issue: 1
Pp: 61-67
Marwa Hassan*, Mohamad A. Ibrahim, Heba M. Hafez, Mervat Z. Mohamed, Nagwa M. Zenhom and Hend M. Abd Elghany
DOI:10.2174/1574884713666180903163558

Metformin and Pregnancy Outcomes: Evidence Gaps and Unanswered Questions open Access plus

Volume: 14   Issue: 1
Pp: 54-60
Claudio D. Gonzalez, Jorge Alvariñas, Maria F.G. Bagnes and Guillermo Di Girolamo*
DOI:10.2174/1574884714666181224151116

Efficacy of Zofenopril Alone or in Combination with Hydrochlorothiazide in Patients with Kidney Dysfunction open Access plus

Volume: 14   Issue: 1
Pp: 5-15
Stefano Omboni* and Claudio Borghi
DOI:10.2174/1574884713666181025145404

Metformin as a Radiation Modifier; Implications to Normal Tissue Protection and Tumor Sensitization open Access plus

Volume: 14   Issue: 1
Pp: 41-53
Keywan Mortezaee, Dheyauldeen Shabeeb, Ahmed E. Musa, Masoud Najafi* and Bagher Farhood*
DOI:10.2174/1574884713666181025141559

Biosimilars: An Approach to some Current Worldwide Regulation Frameworks open Access plus

Volume: 14   Issue: 1
Pp: 16-40
Efraín Esteban, Rosa-Helena Bustos*, Julio-César García and Edwin Jáuregui
DOI:10.2174/1574884713666181025142928

Trends of Clinical Trials for Drug Development in Rare Diseases open Access plus

Volume: 13   Issue: 3
Pp: 199-208
Ryuichi Sakate, Akiko Fukagawa, Yuri Takagaki, Hanayuki Okura and Akifumi Matsuyama*
DOI:10.2174/1574884713666180604081349

Pharmacokinetic and Pharmacodynamic Relationship of Blinatumomab in Patients with Non-Hodgkin Lymphoma open Access plus

Volume: 13   Issue: 1
Pp: 55-64
Youssef Hijazi, Matthias Klinger, Andrea Kratzer, Benjamin Wu, Patrick A. Baeuerle, Peter Kufer, Andreas Wolf, Dirk Nagorsen and Min Zhu*
DOI:10.2174/1574884713666180518102514

Clonidine, but not Dexamethasone, Prolongs Ropivacaine-Induced Supraclavicular Brachial Plexus Nerve Block Duration open Access plus

Volume: 12   Issue: 2
Pp: 92-98
Dawood Nasir*, Irina Gasanova, Shaina Drummond, John Alexander, Jo Howard, Emily Melikman, Gary Hill, Abu Minhajuddin, Babatunde Ogunnaike and Charles Whitten
DOI:10.2174/1574884712666170605085508

Incorporating Natural Products, Pharmaceutical Drugs, Self-Care and Digital/Mobile Health Technologies into Molecular-Behavioral Combination Therapies for Chronic Diseases open Access plus

Volume: 11   Issue: 2
Pp: 128-145
Grzegorz Bulaj, Margaret M. Ahern, Alexis Kuhn, Zachary S. Judkins, Randy C. Bowen and Yizhe Chen
DOI:10.2174/1574884711666160603012237

Ability of older people with dementia or cognitive impairment to manage medicine regimens: a narrative review open Access plus

Volume: 10   Issue: 3
Pp: 213-221
Rohan A. Elliott, Dianne Goeman, Christine Beanland and Susan Koch
DOI:10.2174/1574884710666150812141525

Inappropriate Drug Use in People with Cognitive Impairment and Dementia: A Systematic Review open Access plus

Volume: 10   Issue: 3
Pp: 178-184
Kristina Johnell
DOI:10.2174/1574884710666150609154741

Mucoadhesive Propolis Gel for Prevention of Radiation-Induced Oral Mucositis open Access plus

Volume: 9   Issue: 4
Pp: 359-364
Vladimir R.A.S. Noronha, Gustavo S. Araújo, Rafael T. Gomes, Samara H. Iwanaga, Maralice C. Barbosa, Evandro N. Abdo, Efigenia Ferreira e Ferreira, Ana Cristina Viana Campos, Alexandre A. Souza, Sheila R.L. Abreu and Vagner R. Santos
DOI:10.2174/1574884709666140205210051

Bridging Differences in Outcomes of Pharmacoepidemiological Studies: Design and First Results of the PROTECT Project open Access plus

Volume: 9   Issue: 2
Pp: 130-138
Victoria Abbing-Karahagopian, Xavier Kurz, Frank de Vries, Tjeerd P. van Staa, Yolanda Alvarez, Ulrik Hesse, Joerg Hasford, Liset van Dijk, Francisco J. de Abajo, John G. Weil, Lamiae Grimaldi-Bensouda, Antoine C.G. Egberts, Robert F. Reynolds and Olaf H. Klungel
DOI:10.2174/1574884708666131111211802

The Discovery and Development of Selective Estrogen Receptor Modulators (SERMs) for Clinical Practice open Access plus

Volume: 8   Issue: 2
Pp: 135-155
Philipp Y. Maximov, Theresa M. Lee and V. Craig Jordan
DOI:10.2174/1574884711308020006

Pharmacological Characteristics and Clinical Applications of K201 open Access plus

Volume: 4   Issue: 2
Pp: 126-131
Noboru Kaneko, Ryuko Matsuda, Yoshihito Hata and Ken Shimamoto
DOI:10.2174/157488409788184972

Influence of Enzyme-Inducing Antiepileptic Drugs on Trough Level of Imatinib in Glioblastoma Patients open Access plus

Volume: 3   Issue: 3
Pp: 198-203
Stefan Pursche, Eberhard Schleyer, Malte von Bonin, Gerhard Ehninger, Samir Mustafa Said, Roland Prondzinsky, Thomas Illmer, Yanfeng Wang, Christian Hosius, Zariana Nikolova, Martin Bornhauser and Gregor Dresemann
DOI:10.2174/157488408785747656

The Pharmacokinetics and Pharmacodynamics of Levodopa in the Treatment of Parkinsons Disease open Access plus

Volume: 2   Issue: 3
Pp: 234-243
Soo-Peang Khor and Ann Hsu
DOI:10.2174/157488407781668802

Ethanol Metabolism and Effects: Nitric Oxide and its Interaction open Access plus

Volume: 2   Issue: 2
Pp: 145-153
Xin-Sheng Deng and Richard A. Deitrich
DOI:10.2174/157488407780598135