Abstract
Complex multi-element lead structures of mixed metal oxides that may be identified as hits during high throughput experimentation (HTE) campaigns, can be deconvoluted retrospectively on the basis of simple binary and ternary oxides as illustrated in the current example of a hit found in an ammoxidation reaction. On the basis of the performance of the simple binary and ternary mixed metal oxides structure property relationships can be established, that give insight into the roles of the different components of the complex mixed metal oxides and may also help in establishing a reaction mechanism and converting the hit into a development candidate.
Keywords: Deconvolution, benzene activation, cyclohexane, library planning, Ammoxidation
Combinatorial Chemistry & High Throughput Screening
Title: Retrospective Hit-Deconvolution of Mixed Metal Oxides: Spotting Structure-Property-Relationships in Gas Phase Oxidation Catalysis Through High Throughput Experimentation
Volume: 10 Issue: 1
Author(s): Stephan Andreas Schunk, Andreas Sundermann and Hartmut Hibst
Affiliation:
Keywords: Deconvolution, benzene activation, cyclohexane, library planning, Ammoxidation
Abstract: Complex multi-element lead structures of mixed metal oxides that may be identified as hits during high throughput experimentation (HTE) campaigns, can be deconvoluted retrospectively on the basis of simple binary and ternary oxides as illustrated in the current example of a hit found in an ammoxidation reaction. On the basis of the performance of the simple binary and ternary mixed metal oxides structure property relationships can be established, that give insight into the roles of the different components of the complex mixed metal oxides and may also help in establishing a reaction mechanism and converting the hit into a development candidate.
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Cite this article as:
Andreas Schunk Stephan, Sundermann Andreas and Hibst Hartmut, Retrospective Hit-Deconvolution of Mixed Metal Oxides: Spotting Structure-Property-Relationships in Gas Phase Oxidation Catalysis Through High Throughput Experimentation, Combinatorial Chemistry & High Throughput Screening 2007; 10 (1) . https://dx.doi.org/10.2174/138620707779802832
DOI https://dx.doi.org/10.2174/138620707779802832 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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