Abstract
Assessment of the risks versus the benefits of hormone replacement therapy has become a challenging task for the physicians. Controversial issues have surrounded the status of hormone replacement therapy for postmenopausal women lately. Several randomized controlled trials present contradicting evidences and have raised questions about the short-term risks of long-term benefits of HRT. Evidence from clinical trials like the WHI and HERS trial does not support HRT use for prevention of cardiovascular disease. The review also discusses the association of hormone replacement therapy and cancer, stroke, cognition, cardiovascular disease, venous thromboembolism, osteoprosis, gall bladdaer disease, and quality of life. The latest controversial results of randomized controlled trials in recent years have posed newer challenges for the physicians in prescribing HRT for postmenopausal women.
Keywords: coronary heart disease (CHD), atherosclerosis, venous thromboembolism, Breast Cancer, estrogen, Gall Bladder Disease
Current Drug Therapy
Title: Current Status of Hormone Replacement Therapy in Post Menopausal Women
Volume: 2 Issue: 1
Author(s): Madhur Gupta and Kamlesh Kohli
Affiliation:
Keywords: coronary heart disease (CHD), atherosclerosis, venous thromboembolism, Breast Cancer, estrogen, Gall Bladder Disease
Abstract: Assessment of the risks versus the benefits of hormone replacement therapy has become a challenging task for the physicians. Controversial issues have surrounded the status of hormone replacement therapy for postmenopausal women lately. Several randomized controlled trials present contradicting evidences and have raised questions about the short-term risks of long-term benefits of HRT. Evidence from clinical trials like the WHI and HERS trial does not support HRT use for prevention of cardiovascular disease. The review also discusses the association of hormone replacement therapy and cancer, stroke, cognition, cardiovascular disease, venous thromboembolism, osteoprosis, gall bladdaer disease, and quality of life. The latest controversial results of randomized controlled trials in recent years have posed newer challenges for the physicians in prescribing HRT for postmenopausal women.
Export Options
About this article
Cite this article as:
Gupta Madhur and Kohli Kamlesh, Current Status of Hormone Replacement Therapy in Post Menopausal Women, Current Drug Therapy 2007; 2 (1) . https://dx.doi.org/10.2174/157488507779422419
DOI https://dx.doi.org/10.2174/157488507779422419 |
Print ISSN 1574-8855 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3903 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Editorial: Optimizing Chronic Heart Failure Care Beyond Randomised Controlled Trials – What are the problem areas and potential solutions?
Current Cardiology Reviews Drug-Lipid Membrane Interaction Mechanisms Revealed Through Molecular Simulations
Current Physical Chemistry HDL - Cholesterol: The New Target for Treatment
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Lipid-based Vesicular Nanocargoes as Nanotherapeutic Targets for the Effective Management of Rheumatoid Arthritis
Recent Patents on Anti-Infective Drug Discovery Mitochondrially Targeted Antioxidants for the Treatment of Cardiovascular Diseases
Recent Patents on Cardiovascular Drug Discovery Nursing Assessment, Education, and Care of Extremely Premature Neonates with Patent Ductus Arteriosus
Current Pediatric Reviews Insights from Exercise-induced Cardioprotection-from Clinical Application to Basic Research
Current Pharmaceutical Design Diagnostic Cardiac Catheterization in the Pediatric Population
Current Cardiology Reviews Integrin (αvβ3) Targeted RGD Peptide Based Probe for Cancer Optical Imaging
Current Protein & Peptide Science Soluble Forms of RAGE in Human Diseases: Clinical and Therapeutical Implications
Current Medicinal Chemistry Periodontitis and Atherosclerosis, a Causal Relationship?
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Selective Serotonin Re-Uptake Inhibitors and Hyponatremia in Acutely Medically-Ill Inpatients
Current Drug Safety Recent Advances in Metabolomics
Current Metabolomics An Overview on COVID-19 and its Effect on Cardiovascular Diseases
Endocrine, Metabolic & Immune Disorders - Drug Targets SIRT1, a Calorie Restriction Mimetic, in a New Therapeutic Approach for Type 2 Diabetes Mellitus and Diabetic Vascular Complications
Endocrine, Metabolic & Immune Disorders - Drug Targets Almonds: A Source of Healthy Molecules or a Risk of Aflatoxins Human Exposure?
Current Nutrition & Food Science Bioactive Fish Fatty Acids: Health Effects and Their Use as Functional Food Ingredients
Current Nutrition & Food Science The Biology of the RNA Binding Protein Guanine-Rich Sequence Binding Factor 1
Current Protein & Peptide Science Heart Rate Variability Analysis at Coronary Artery Disease and Angina Pectoris
Recent Patents on Cardiovascular Drug Discovery Cardiac Regeneration: Stem Cells and Beyond
Current Medicinal Chemistry