Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting, Lawrence

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Serum-Stable RNA Aptamers to an Invariant Surface Domain of Live African Trypanosomes

Volume:9   Issue: 7
Pp: 491-499
H. Ulrich Goringer, Martin Zacharias, Markus Engstler, Matthias Homann and Mihaela Lorger
DOI: 10.2174/138620706777935324

Design and Characterization of a Functional Library for NMR Screening Against Novel Protein Targets

Volume:9   Issue: 7
Pp: 515-534
Robert Powers, Katherine Germer and Kelly A. Mercier
DOI: 10.2174/138620706777935342

Synthesis of Metallothionein-Mimic Decapeptides with Heavy Atom Signaling Properties

Volume:9   Issue: 7
Pp: 535-544
Marta E. Diaz-Garcia, Ignacio A. Rivero and Tania Gonzalez
DOI: 10.2174/138620706777935315

Exploring Structure-Activity Relationships of Tricyclic Farnesyltransferase Inhibitors Using ECLiPS® Libraries

Volume:9   Issue: 7
Pp: 545-558
Laura L. Rokosz, Chia-Yu Huang, John C. Reader, Tara M. Stauffer, Eileen C. Southwick, Ge Li, Daniel Chelsky and John J. Baldwin
DOI: 10.2174/138620706777935379

A Gradient Descent Algorithm for Minimizing Amino Acid Coupling Reactions when Synthesizing Cyclic-Peptide Libraries

Volume:9   Issue: 7
Pp: 559-563
Paul J. Darwen, Tran T. Tran, Gregory T. Bourne, Jonathon L. Nielson and Mark L. Smythe
DOI: 10.2174/138620706777935333

A Directly Labeled TR-FRET Assay for Monitoring Phosphoinositide-3-Kinase Activity

Volume:9   Issue: 7
Pp: 565-570
Xiaoke Yang, Puyao Li, Larry Feldberg, Steven C. Kim, Michael Bowman, Irwin Hollander, Robert Mallon and Stanley F. Wolf
DOI: 10.2174/138620706777935360