Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting
Lawrence, KS

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Volume: 9 Issue: 4, May

Editorial [Hot Topic:Directed Evolution Approaches for Protein Engineering (Guest Editor: Edgardo T. Farinas)]

Volume:9   Issue: 4
Pp: 235-236
Edgardo T. Farinas
DOI: 10.2174/138620706776843165

Optimizing a Biocatalyst for Improved NAD(P)H Regeneration: Directed Evolution of Phosphite Dehydrogenase

Volume:9   Issue: 4
Pp: 237-245
Ryan Woodyer, Wilfred A. van der Donk and Huimin Zhao
DOI: 10.2174/138620706776843246

Recent Advances in Biocatalysis by Directed Enzyme Evolution

Volume:9   Issue: 4
Pp: 247-257
Sheryl B. Rubin-Pitel and Huimin Zhao
DOI: 10.2174/138620706776843183

Towards the Creation of Novel Proteins by Block Shuffling

Volume:9   Issue: 4
Pp: 259-269
Toru Tsuji, Michiko Onimaru and Hiroshi Yanagawa
DOI: 10.2174/138620706776843237

The Diversity Challenge in Directed Protein Evolution

Volume:9   Issue: 4
Pp: 271-288
Tuck S. Wong, Daria Zhurina and Ulrich Schwaneberg
DOI: 10.2174/138620706776843192

A Filter Paper-Based Assay for Laboratory Evolution of Hydrolases and Dehydrogenases

Volume:9   Issue: 4
Pp: 289-293
Tuck S. Wong, Ulrich Schwaneberg, Rainer Sturmer, Bernhard Hauer and Michael Breuer
DOI: 10.2174/138620706776843228

High-Throughput Selection System for Assessing the Activity of Epoxide Hydrolases

Volume:9   Issue: 4
Pp: 295-299
Manfred T. Reetz and Li-Wen Wang
DOI: 10.2174/138620706776843156

A Bacterial One-Hybrid Selection System for Interrogating Zinc Finger- DNA Interactions

Volume:9   Issue: 4
Pp: 301-311
Sundar Durai, Allen Bosley, Alice B. Abulencia, Srinivasan Chandrasegaran and Marc Ostermeier
DOI: 10.2174/138620706776843147

HIV Protease-Activated Molecular Switches Based on Beta-Glucuronidase and Alkaline Phosphatase

Volume:9   Issue: 4
Pp: 313-320
Taryn L. O'Loughlin and Ichiro Matsumura
DOI: 10.2174/138620706776843219

Fluorescence Activated Cell Sorting for Enzymatic Activity

Volume:9   Issue: 4
Pp: 321-328
Edgardo T. Farinas
DOI: 10.2174/138620706776843200

Meet the Guest Editor

Volume:9   Issue: 4
Pp: 329-329
Edgardo T. Farinas
DOI: 10.2174/138620706776843174