Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Editor-in-Chief

Gerald H. Lushington
LiS Consulting, Lawrence
KS
(USA)

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Volume: 5 Issue: 1, February

Preface

Volume:5   Issue: 1
Pp: i-i
Richard B. van Breemen
DOI: 10.2174/1386207023330552
Published on: 01 March, 2012

Random Sequence Libraries Displayed on Phage: Identification of Biologically Important Molecules

Volume:5   Issue: 1
Pp: 1-14
Christopher G. Adda, Robin F. Anders, Leann Tilley and Michael Foley
DOI: 10.2174/1386207023330561
Published on: 01 March, 2012

Mimotopes of Viral Antigens and Biologically Important Molecules as Candidate Vaccines and Potential Immunotherapeutics

Volume:5   Issue: 1
Pp: 15-27
C. D. Partidos and M. W. Steward
DOI: 10.2174/1386207023330589
Published on: 01 March, 2012

Rapid Determination of Pharmacokinetic Properties of New Chemical Entities: In vivo Approaches

Volume:5   Issue: 1
Pp: 29-37
Kathleen A. Cox, Ronald E. White and Walter A. Korfmacher
DOI: 10.2174/1386207023330534
Published on: 01 March, 2012

A Systematic SAR Study of C10 Modified Paclitaxel Analogues Using a Combinatorial Approach

Volume:5   Issue: 1
Pp: 39-48
Yanbin Liu, Syed M. Ali, Thomas C. Boge, Gunda I. Georg, Samuel Victory, Jan Zygmunt, Rebecca T. Marquez and Richard H. Himes
DOI: 10.2174/1386207023330615
Published on: 01 March, 2012

Molecular Diversity Sample Generation on the Basis of Quantum-Mechanical Computations and Principal Component Analysis

Volume:5   Issue: 1
Pp: 49-57
H. Gutierrez-de-Teran, J. J. Lozano, V. Segarra and F. Sanz
DOI: 10.2174/1386207023330543
Published on: 01 March, 2012

Screening Drugs for Metabolic Stability Using Pulsed Ultrafiltration Mass Spectrometry

Volume:5   Issue: 1
Pp: 59-64
Young Geun Shin, Judy L. Bolton and Richard B. Van Breemen
DOI: 10.2174/1386207023330633
Published on: 01 March, 2012

Evaluation of a Micro Volume Pulsed Ultrafiltration Cell for Screening Ligands in Non-Covalent Complexes

Volume:5   Issue: 1
Pp: 65-73
Michael B. Beverly, Paul West and Randy K. Julian
DOI: 10.2174/1386207023330606
Published on: 01 March, 2012

Solid-Phase and Solution-Phase Parallel Synthesis of Tetrahydro-isoquinolines via Pictet-Spengler Reaction

Volume:5   Issue: 1
Pp: 75-81
Qun Sun and Donald J. Kyle
DOI: 10.2174/1386207023330624
Published on: 01 March, 2012

Recognition of Multiple Substrate Motifs by the c-ABL Protein Tyrosine Kinase

Volume:5   Issue: 1
Pp: 83-91
Jinzi J. Wu, Daniel E.H. Afar, Hoang Phan, Owen N. Witte and Kit S. Lam
DOI: 10.2174/1386207023330516
Published on: 01 March, 2012

Solid Phase Synthesis of Structurally Diverse Tetra Substituted Pyrimidines for Potential Use in Combinatorial Chemistry

Volume:5   Issue: 1
Pp: 93-95
P. M.S. Chauhan and Arun Kumar
DOI: 10.2174/1386207023330525
Published on: 01 March, 2012

Author Index To Volume 4

Volume:5   Issue: 1
Pp: 97-99
Science Publishers Bentham
DOI: 10.2174/1386207023330570
Published on: 01 March, 2012

subject Index To Volume 4

Volume:5   Issue: 1
Pp: 101-103
Science Publishers Bentham
DOI: 10.2174/1386207023330598
Published on: 01 March, 2012