Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting, Lawrence

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Editorial: Mining for Pharmacophores in Phenotypic Screens free to download

Volume:17   Issue: 8
Pp: 651-651
Gerald Henry Lushington
DOI: 10.2174/138620731708140922155612
Published on: 22 September, 2014

An Efficient Synthetic Method and Theoretical Calculations of Olmesartan Methyl Ether: Study of Biological Function of AT1 Antagonism

Volume:17   Issue: 8
Pp: 652-662
Dimitrios Ntountaniotis, George Agelis, Amalia Resvani, Maria Halabalaki, George Liapakis, Katerina Spyridaki, Simona Golic Grdadolnik, Franci Merzel, Sarantos Kostidis, Constantinos Potamitis, Theodore Tselios, John Matsoukas, Leandros Alexios Skaltsounis and Thomas Mavromoustakos
DOI: 10.2174/138620731708140922171503
Published on: 22 September, 2014

E-Pharmacophore and Molecular Dynamics Study of Flavonols and Dihydroflavonols as Inhibitors Against DiHydroOrotate DeHydrogenase

Volume:17   Issue: 8
Pp: 663-673
Priya Swaminathan, Sukesh Kalva and Lilly M. Saleena
DOI: 10.2174/1386207317666140321115128
Published on: 22 September, 2014

Stabilization of Carbenes via α-Ylide Substitutions: A Computational Quest for New Divalents at DFT

Volume:17   Issue: 8
Pp: 674-680
Bibi Narjes Haerizade, Mohammad Zaman Kassaee, Maryam Koohi, Monire Ghavami and Hassan Zandi
DOI: 10.2174/1386207317666140422155343
Published on: 22 September, 2014

In Silico Screening of Antifolate Based Novel Inhibitors from Brucea mollis Wall. ex kurz Against Quadruple Mutant Drug Resistant PfDHFR

Volume:17   Issue: 8
Pp: 681-693
Biswajyoti Borkakoty, Kishore Sarma, Pratap Parida, Anil Prakash, Pradyumna Kishore Mohapatra and Jagadish Mahanta
DOI: 10.2174/1386207317666140521153305
Published on: 22 September, 2014

In Vitro Selection of a Single-Stranded DNA Molecular Recognition Element for the Pesticide Malathion

Volume:17   Issue: 8
Pp: 694-702
Ryan M. Williams, Eamonn Maher and Letha J. Sooter
DOI: 10.2174/1386207317666140827123631
Published on: 22 September, 2014

A Theoretical Study on the Reaction Pathways and the Mechanism of 1,3- Dipolar Cycloaddition of Vinyl Acetylene and Methyl Azide

Volume:17   Issue: 8
Pp: 703-708
Seyyed Amir Siadati, Ali Mahboobifar and Ramin Nasiri
DOI: 10.2174/138620731708140922163855
Published on: 22 September, 2014

Isolation and Biological Evaluation of Novel Tetracosahexaene Hexamethyl, an Acyclic Triterpenoids Derivatives and Antioxidant from Justicia adhatoda

Volume:17   Issue: 8
Pp: 723-732
Sandeep Dhankhar, Seema Dhankhar, Sonam Ruhil, Meenakshi Balhara, Vinay Malik and Anil K. Chhillar
DOI: 10.2174/1386207317666140708091552
Published on: 22 September, 2014