Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Editor-in-Chief

Gerald H. Lushington
LiS Consulting, Lawrence
KS
(USA)

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Editorial: Rediscovering Drug Discovery free to download

Volume:17   Issue: 10
Pp: 819-819
Bhushan Patwardhan
DOI: 10.2174/138620731710150108230829
Published on: 08 January, 2015

The Application of Connected QSRR and QSAR Strategies to Predict the Physicochemical Interaction of Acridinone Derivatives with DNA

Volume:17   Issue: 10
Pp: 820-826
Paulina Szatkowska-Wandas, Marcin Koba, Agata Kuchcicka, Sylwia Kurek, Emilia Daghir-Wojtkowiak and Tomasz Baczek
DOI: 10.2174/1386207317666141112120743
Published on: 08 January, 2015

Rapid Screening of Different Types of Antitumor Compound Groups from Traditional Chinese Medicine by Hollow Fiber Cell Fishing with High Performance Liquid Chromatography

Volume:17   Issue: 10
Pp: 827-836
Li-Sha Zhang, Xuan Chen, Shuang Hu, Xia Sheng and Xiao-Hong Bai
DOI: 10.2174/1386207317666141031101709
Published on: 08 January, 2015

Design Novel Inhibitors for Treating Cancer by Targeting Cdc25B Catalytic Domain with De Novo Design

Volume:17   Issue: 10
Pp: 837-847
Jing-Wei Wu, Huan Zhang, Yu-Qing Duan, Wei-Li Dong, Xian-Chao Cheng, Shu-Qing Wang and Run-Ling Wang
DOI: 10.2174/1386207317666141029223505
Published on: 08 January, 2015

Ligand-Based Pharmacophore Modeling, Atom-Based 3D-QSAR and Molecular Docking Studies on Substituted Thiazoles and Thiophenes as Polo-Like Kinase 1 (Plk1) Inhibitors

Volume:17   Issue: 10
Pp: 848-858
Rajasekhar Chekkara, Venkata Reddy Gorla, Ethiraj Susithra and Sobha Rani Tenkayala
DOI: 10.2174/1386207317666141024152910
Published on: 08 January, 2015

In Vitro High Throughput Phage Display Selection of Ovarian Cancer Avid Phage Clones for Near-Infrared Optical Imaging

Volume:17   Issue: 10
Pp: 859-867
Mette Soendergaard, Jessica R. Newton-Northup and Susan L. Deutscher
DOI: 10.2174/1386207317666141031152828
Published on: 08 January, 2015

Discovery of Novel NAMPT Inhibitors Based on Pharmacophore Modeling and Virtual Screening Techniques

Volume:17   Issue: 10
Pp: 868-878
Qianying Yi, Lu Zhou, Xin Shao, Taijin Wang, Guangkai Bao, Huanhuan Shi, Suwen Zhou, Xiaoli Li and Yahui Tian
DOI: 10.2174/1386207317666141121124139
Published on: 08 January, 2015

Molecular Structural Characteristics Important in Drug-HSA Binding

Volume:17   Issue: 10
Pp: 879-890
Snezana Agatonovic-Kustrin, David W. Morton, Lisa Truong and Slavica Razic
DOI: 10.2174/1386207317666141114222955
Published on: 08 January, 2015

Molecular Docking and Dynamics Simulation Study on the Influence of Zn2+ on the Binding Modes of Aggrecanase with its Inhibitors

Volume:17   Issue: 10
Pp: 891-903
Panneer S.R. Suganya, Sukesh kalva and Lilly M. Saleena
DOI: 10.2174/1386207317666141113155141
Published on: 08 January, 2015

Acknowledgements to Reviewers: promotion: free to download

Volume:17   Issue: 10
Pp: 904-904

DOI: 10.2174/138620731710150109001554
Published on: 08 January, 2015