Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting, Lawrence

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Mapping Fragmental Drug-Likeness in the MoStBioDat Environment:Intramolecular Hydrogen Bonding Motifs in β-Ketoenols

Volume:14   Issue: 7
Pp: 560-569
Andrzej Bak, Tomasz Magdziarz, Agata Kurczyk and Jaroslaw Polanski
DOI: 10.2174/138620711796367193

Supported TBD-Assisted Solution Phase Diversification of Formyl-Aza-Heterocycles Through Alkylation-Knoevenagel One Pot Sequences

Volume:14   Issue: 7
Pp: 570-582
Abdelaziz El Maatougui, Abel Crespo, Artur M.S. Silva and Alberto Coelho
DOI: 10.2174/138620711796367229

A Fluorescence Polarization Based Screening Assay for Identification of Small Molecule Inhibitors of the PICK1 PDZ Domain

Volume:14   Issue: 7
Pp: 590-600
Thor S. Thorsen, Kenneth L. Madsen, Tino Dyhring, Anders Bach, Dan Peters, Kristian Stromgaard and Ulrik Gether
DOI: 10.2174/138620711796367201

Quantitative Structure-Wavelength Relationship Modeling of Porphin -Derivative Photosensitizers

Volume:14   Issue: 7
Pp: 601-615
Ping Han, Feng Luan, Yuan Gao, Jinjun Wang and Huitao Liu
DOI: 10.2174/138620711796367256

Alternative Medicine Safety: Agaricus blazei and Propolis open access plus

Volume:14   Issue: 7
Pp: 616-621
Kenji Sorimachi* and Takaaki Nakamoto
DOI: 10.2174/138620711796367238

Development of Naturally Selected and Molecularly Engineered Intrachain and Competitive FRET-Aptamers and Aptamer Beacons

Volume:14   Issue: 7
Pp: 622-630
John G. Bruno, Miguel A. Zuniga, Maria P. Carrillo and Taylor Phillips
DOI: 10.2174/138620711796367175

Identification and Characterization of mGlu3 Ligands Using a High Throughput FLIPR Assay for Detection of Agonists, Antagonists, and Allosteric Modulators

Volume:14   Issue: 7
Pp: 631-641
Steven D. Pratt, Mario Mezler, Herve Geneste, Margot H.M. Bakker, Philip J. Hajduk and Sujatha M. Gopalakrishnan
DOI: 10.2174/138620711796367184

Patent Review promotion: free to download

Volume:14   Issue: 7
Pp: 642-644
James E. McGee and Anuradha Roy
DOI: 10.2174/138620711796367210