Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting, Lawrence

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Volume: 13 Issue: 1, January


Volume:13   Issue: 1
Pp: 1-2
Richard B. van Breemen
DOI: 10.2174/138620710790218221
Published on: 01 March, 2012

High Content Screening of CXCR2-Dependent Signalling Pathways

Volume:13   Issue: 1
Pp: 3-15
Michael Wolff, Simone Krede, Dorothea Haasen, Jorg Wiedenmann, G. Ulrich Nienhaus, Barbara Kistler, Franz Oswald and Ralf Heilker
DOI: 10.2174/138620710790218249
Published on: 01 March, 2012

Efficient Identification of Novel Leads by Dynamic Focused Screening: PDK1 Case Study

Volume:13   Issue: 1
Pp: 16-26
Dongyu Sun, Joon Jung, Thomas S. Rush III, Zangwei Xu, Michael J. Weber, Ekaterina Bobkova, Alan Northrup and Ilona Kariv
DOI: 10.2174/138620710790218186
Published on: 01 March, 2012

A Universal, Fully Automated High Throughput Screening Assay for Pyrophosphate and Phosphate Release from Enzymatic Reactions

Volume:13   Issue: 1
Pp: 27-38
Scott D. Pegan, Yang Tian, Valerie Sershon and Andrew D. Mesecar
DOI: 10.2174/138620710790218203
Published on: 01 March, 2012

Prediction of Critical Micelle Concentration of Nonionic Surfactants by a Quantitative Structure – Property Relationship

Volume:13   Issue: 1
Pp: 39-44
Anna Mozrzymas and Bozenna Rozycka-Roszak
DOI: 10.2174/138620710790218195
Published on: 01 March, 2012

Tagging Molecules with Linear Polymers: Biocatalytic Transformation of Substrates Anchored on Soluble Macromolecules

Volume:13   Issue: 1
Pp: 45-53
Claudio Cornaggia and Dario Pasini
DOI: 10.2174/138620710790218177
Published on: 01 March, 2012

Applications of Integrated Data Mining Methods to Exploring Natural Product Space for Acetylcholinesterase Inhibitors

Volume:13   Issue: 1
Pp: 54-66
Daniela Schuster, Lisa Kern, Dimitar P. Hristozov, Lothar Terfloth, Bruno Bienfait, Christian Laggner, Johannes Kirchmair, Ulrike Grienke, Gerhard Wolber, Thierry Langer, Hermann Stuppner, Johann Gasteiger and Judith M. Rollinger
DOI: 10.2174/138620710790218212
Published on: 01 March, 2012

High Throughput Synthesis and Screening of New Catalytic Materials for the Direct Epoxidation of Propylene

Volume:13   Issue: 1
Pp: 67-74
Michael Kahn, Anusorn Seubsai, Isik Onal and Selim Senkan
DOI: 10.2174/138620710790218230
Published on: 01 March, 2012

Phage-Displayed Combinatorial Peptide Libraries in Fusion to β-Lactamase as Reporter for an Accelerated Clone Screening: Potential Uses of Selected Enzyme-Linked Affinity Reagents in Downstream Applications

Volume:13   Issue: 1
Pp: 75-87
Girja S. Shukla and David N. Krag
DOI: 10.2174/138620710790218258
Published on: 01 March, 2012