Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting, Lawrence

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Screening of Antioxidant Phenolic Compounds Produced by In Vitro Shoots of Brassica oleracea L. var. costata DC

Volume:12   Issue: 3
Pp: 230-240
Federico Ferreres, Carla Sousa, David M. Pereira, Patricia Valentao, Marcos Taveira, Anabela Martins, Jose A. Pereira, Rosa M. Seabra and Paula B. Andrade
DOI: 10.2174/138620709787581756

The Four Human γ-Aminobutyric Acid (GABA) Transporters: Pharmacological Characterization and Validation of a Highly Efficient Screening Assay

Volume:12   Issue: 3
Pp: 241-249
Trine Kvist, Bolette Christiansen, Anders A. Jensen and Hans Brauner-Osborne
DOI: 10.2174/138620709787581684

Development and Validation of a High-Density Fluorescence Polarization-Based Assay for the Trypanosoma RNA Triphosphatase TbCet1

Volume:12   Issue: 3
Pp: 258-268
Christophe Antczak, David Shum, Constantin Radu, Venkatraman E. Seshan and Hakim Djaballah
DOI: 10.2174/138620709787581729

Narrowing Laccase Substrate Specificity Using Active Site Saturation Mutagenesis

Volume:12   Issue: 3
Pp: 269-274
Nirupama Gupta and Edgardo T. Farinas
DOI: 10.2174/138620709787581675

A Multi-Step NMR Screen for the Identification and Evaluation of Chemical Leads for Drug Discovery

Volume:12   Issue: 3
Pp: 285-295
Kelly A. Mercier, Matthew D. Shortridge and Robert Powers
DOI: 10.2174/138620709787581738

High Throughput Screening Assay of α1G T-type Ca2+ Channels and Comparison with Patch-Clamp Studies

Volume:12   Issue: 3
Pp: 296-302
Yoonjee Kim, Soonja Kang, Jae Yeol Lee and Hyewhon Rhim
DOI: 10.2174/138620709787581710

Docking-Based Virtual Screening: Recent Developments

Volume:12   Issue: 3
Pp: 303-314
Tiziano Tuccinardi
DOI: 10.2174/138620709787581666