Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Editor-in-Chief

Gerald H. Lushington
LiS Consulting, Lawrence
KS
(USA)

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Editorial [Hot Topic: Ion Channels: Applications in Ion Channel Drug Discovery(Guest Editor: Douglas S. Krafte)] promotion: free to download

Volume:12   Issue: 1
Pp: 1-1
Douglas S. Krafte
DOI: 10.2174/138620709787048046

Evolution of the Human Ion Channel Set promotion: free to download

Volume:12   Issue: 1
Pp: 2-23
Surendra K. Nayak, Serge Batalov, Timothy J. Jegla and Christian M. Zmasek
DOI: 10.2174/138620709787047957

Port-a-Patch and Patchliner: High Fidelity Electrophysiology for Secondary Screening and Safety Pharmacology promotion: free to download

Volume:12   Issue: 1
Pp: 24-37
Niels Fertig, Andrea Bruggemann, Mohamed Kreir, Michael George, Sonja Stoelzle, Claudia Haarmann, Cecilia Farre and Alison Haythornthwaite
DOI: 10.2174/138620709787047966

High Throughput Electrophysiology with Xenopus Oocytes promotion: free to download

Volume:12   Issue: 1
Pp: 38-50
Cathy Smith-Maxwell and Roger L. Papke
DOI: 10.2174/138620709787047975

Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels promotion: free to download

Volume:12   Issue: 1
Pp: 51-63
Mads P.G. Korsgaard, Dorte Strobaek and Palle Christophersen
DOI: 10.2174/138620709787048037

HCN Channels as Targets for Drug Discovery promotion: free to download

Volume:12   Issue: 1
Pp: 64-72
Alan D. Wickenden, Sandra R. Chaplan, Adrienne E. Dubin, Hong-Qing Guo, Nyan-Tsz Wu and Michael P. Maher
DOI: 10.2174/138620709787048028

The Chiptip: A Novel Tool for Automated Patch Clamp promotion: free to download

Volume:12   Issue: 1
Pp: 73-77
Andjelko Golubovic, Martina Knirsch, Uwe Czubayko, Alexander Hummer, Albrecht Lepple-Wienhues and Dirck Lassen
DOI: 10.2174/138620709787047984

QPatch: The Missing Link Between HTS and Ion Channel Drug Discovery promotion: free to download

Volume:12   Issue: 1
Pp: 78-95
Yi Liu, Chris Mathes, Soren Friis and Michael Finley
DOI: 10.2174/138620709787047948

Use of Planar Array Electrophysiology for the Development of Robust Ion Channel Cell Lines promotion: free to download

Volume:12   Issue: 1
Pp: 96-106
Jeffrey J. Clare, Mao Xiang Chen, David L. Downie, Derek J. Trezise and Andrew J. Powell
DOI: 10.2174/138620709787048000

Sodium Channel Inhibitor Drug Discovery Using Automated High Throughput Electrophysiology Platforms promotion: free to download

Volume:12   Issue: 1
Pp: 107-122
Neil Castle, David Printzenhoff, Shannon Zellmer, Brett Antonio, Alan Wickenden and Christopher Silvia
DOI: 10.2174/138620709787047993

Meet The Guest Editor promotion: free to download

Volume:12   Issue: 1
Pp: 123-123
Douglas S. Krafte
DOI: 10.2174/138620709787048019