Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting, Lawrence

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Integrating Chemists Preferences for Shape-Similarity Clustering of Series

Volume:11   Issue: 4
Pp: 266-282
Laurent A. Baumes, Remi Gaudin, Pedro Serna, Nicolas Nicoloyannis and Avelino Corma
DOI: 10.2174/138620708784246068

High-Content Screening and Mechanism-Based Evaluation of Estrogenic Botanical Extracts

Volume:11   Issue: 4
Pp: 283-293
Cassia R. Overk, Ping Yao, Shaonong Chen, Shixing Deng, Ayano Imai, Matthew Main, Andreas Schinkovitz, Norman R. Farnsworth, Guido F. Pauli and Judy L. Bolton
DOI: 10.2174/138620708784246022

Alkylsquarates as Key Intermediates for the Rapid Preparation of Original Drug-Inspired Compounds

Volume:11   Issue: 4
Pp: 294-303
Julie Charton, Lise Charruault, Rebecca Deprez-Poulain and Benoit Deprez
DOI: 10.2174/138620708784246013

Pharmacological Characterization of Ligands at Recombinant NMDA Receptor Subtypes by Electrophysiological Recordings and Intracellular Calcium Measurements open access plus

Volume:11   Issue: 4
Pp: 304-315
Kasper B. Hansen*, Hans Brauner-Osborne and Jan Egebjerg
DOI: 10.2174/138620708784246040

Functional Human 5-HT6 Receptor Assay for High Throughput Screening of Chemical Ligands and Binding Proteins

Volume:11   Issue: 4
Pp: 316-324
Hyun-Ji Kim, Hyung-Mun Yun, Taehyun Kim, Ghilsoo Nam, Eun Joo Roh, Evi Kostenis, Hea-Young Park Choo, Ae Nim Pae and Hyewhon Rhim
DOI: 10.2174/138620708784246059