Current Cancer Drug Targets

Resveratrol as an Adjuvant for Normal Tissues Protection and Tumor Sensitization

Volume:20   Issue:2
Pp: 130-145
Keywan Mortezaee, Masoud Najafi*, Bagher Farhood*, Amirhossein Ahmadi*, Dheyauldeen Shabeeb and Ahmed E. Musa
DOI: 10.2174/1568009619666191019143539

Natural DNA Intercalators as Promising Therapeutics for Cancer and Infectious Diseases

Volume:20   Issue:1
Pp: 19-32
Martyna Godzieba* and Slawomir Ciesielski
DOI: 10.2174/1568009619666191007112516

Old and New Approaches to Target the Hsp90 Chaperone

Volume:20   Issue:4
Pp: 253-270
Jackee Sanchez, Trever R. Carter, Mark S. Cohen* and Brian S.J. Blagg
DOI: 10.2174/1568009619666191202101330

circEPSTI1 Acts as a ceRNA to Regulate the Progression of Osteosarcoma

Volume:20   Issue:4
Pp: 288-294
Xinyu Tan, Duxun Tan, Haomiao Li, Ye Lin, Zhishen Wen and Canjun Zeng*
DOI: 10.2174/1568009619666191107140948

COVID-19 Pandemic: Experiences in China and Implications for its Prevention and Treatment Worldwide

Volume:20   Issue:6
Pp: 410-416
Ning-Ning Liu*, Jing-Cong Tan, Jingquan Li, Shenghui Li*, Yong Cai* and Hui Wang*
DOI: 10.2174/1568009620666200414151419

CDK12 Promotes Breast Cancer Progression and Maintains Stemness by Activating c-myc/β -catenin Signaling

Volume:20   Issue:2
Pp: 156-165
Fang Peng, Chuansheng Yang, Yanan Kong, Xiaojia Huang, Yanyu Chen, Yangfan Zhou, Xinhua Xie* and Peng Liu*
DOI: 10.2174/1568009619666191118113220

Anti-VEGF/VEGFR2 Monoclonal Antibodies and their Combinations with PD-1/PD-L1 Inhibitors in Clinic

Volume:20   Issue:1
Pp: 3-18
Feng Gao* and Chun Yang
DOI: 10.2174/1568009619666191114110359

Cancer Cell-derived Secretory Factors in Breast Cancer-associated Lung Metastasis: Their Mechanism and Future Prospects open access plus

Volume:20   Issue:3
Pp: 168-186
Tabinda Urooj*, Bushra Wasim, Shamim Mushtaq, Syed Nudrat Nawaid Shah and Muzna Shah
DOI: 10.2174/1568009620666191220151856

Effects of Intermittent Hypoxia on Expression of Glucose Metabolism Genes in MCF7 Breast Cancer Cell Line

Volume:20   Issue:3
Pp: 216-222
Yazun Jarrar, Malek Zihlif*, Abdel Qader Al Bawab and Ahmad Sharab
DOI: 10.2174/1568009619666191116095847

HOTAIR Competitively Binds MiRNA330 as a Molecular Sponge to Increase the Resistance of Gastric Cancer to Trastuzumab

Volume:20   Issue:9
Pp: 700-709
Liangyu Bie, Suxia Luo*, Dan Li, Yan Wei, Yu Mu, Xiaobing Chen, Saiqi Wang, Ping Guo and Xiaoyu Lu
DOI: 10.2174/1568009620666200504114000

Overexpression of p62 Induces Autophagy and Promotes Proliferation, Migration and Invasion of Nasopharyngeal Carcinoma Cells through Promoting ERK Signaling Pathway

Volume:20   Issue:8
Pp: 624-637
Qiong Wu, Manlin Xiang, Kun Wang, Zhen Chen, Lu Long, Ya Tao, Yunlai Liang, Yahui Yan, Zhiqiang Xiao, Shiyang Qiu and Bin Yi*
DOI: 10.2174/1568009620666200424145122

Novel Homeodomain Transcription Factor Nkx2.2 in the Brain Tumor Development

Volume:20   Issue:5
Pp: 335-340
Mubeena P.M. Mariyath, Mehdi H. Shahi*, Shirin Farheen, Mohd Tayyab, Nabeela Khanam and Asif Ali
DOI: 10.2174/1568009618666180102111539

C/EBPα Regulates FOXC1 to Modulate Tumor Growth by Interacting with PPARγ in Hepatocellular Carcinoma

Volume:20   Issue:1
Pp: 59-66
Zhuo Xu, Shao-Hua Meng, Jian-Guo Bai, Chao Sun*, Li-Li Zhao*, Rui-Feng Tang, Zhao-Lin Yin, Jun-Wei Ji, Wei Yang and Guang-Jun Ma
DOI: 10.2174/1568009619666190912161003

Exosome as a Natural Gene Delivery Vector for Cancer Treatment

Volume:20   Issue:11
Pp: 821-830
Prasad Pofali, Adrita Mondal and Vaishali Londhe*
DOI: 10.2174/1568009620666200924154149

VS-5584 Inhibits Human Osteosarcoma Cells Growth by Induction of G1- phase Arrest through Regulating PI3K/mTOR and MAPK Pathways

Volume:20   Issue:8
Pp: 616-623
Jing-Yi Sun, Ya-Jun Hou, Hai-Juan Cui, Cheng Zhang, Ming-Feng Yang, Feng-Ze Wang, Zheng Sun, Cun-Dong Fan*, Bao-Liang Sun* and Jin Rok Oh*
DOI: 10.2174/1568009620666200414150353

CircRNA SCARB1 Promotes Renal Cell Carcinoma Progression Via Mir- 510-5p/SDC3 Axis

Volume:20   Issue:6
Pp: 461-470
Jijian Sun*, Shijie Pan, Hongquan Cui and Hao Li
DOI: 10.2174/1568009620666200409130032

Lipid-based Nanoplatforms in Cancer Therapy: Recent Advances and Applications

Volume:20   Issue:4
Pp: 271-287
Kuldeep Rajpoot*
DOI: 10.2174/1568009620666200115160805

Disintegrin Tablysin-15 Suppresses Cancer Hallmarks in Melanoma Cells by Blocking FAK/Akt/ERK and NF-κB Signaling

Volume:20   Issue:4
Pp: 306-315
Zhenhui Deng, Qingye Zeng, Jinwei Chai, Bei Zhang, Wenhong Zheng, Xueqing Xu* and Jiguo Wu*
DOI: 10.2174/1568009620666200101094736

Use of Small-molecule Inhibitory Compound of PERK-dependent Signaling Pathway as a Promising Target-based Therapy for Colorectal Cancer

Volume:20   Issue:3
Pp: 223-238
Wioletta Rozpędek, Dariusz Pytel, Adam Wawrzynkiewicz, Natalia Siwecka, Adam Dziki, Łukasz Dziki, J. Alan Diehl and Ireneusz Majsterek*
DOI: 10.2174/1568009620666200106114826

Sam68 Promotes the Progression of Human Breast Cancer through inducing Activation of EphA3

Volume:20   Issue:1
Pp: 76-83
Xinxin Chen*, Lehong Zhang*, Min Yuan, Ziqiao Kuang, Ying Zou, Tian Tang, Wangjian Zhang, Xiaowu Hu, Ting Xia , Tengfei Cao and Haixia Jia
DOI: 10.2174/1568009619666190718124541

Clinical Outcomes and Safety of Patients Treated with NAb-Paclitaxel Plus Gemcitabine in Metastatic Pancreatic Cancer: The NAPA Study

Volume:20   Issue:11
Pp: 887-895
Martina Catalano, Giandomenico Roviello*, Raffaele Conca, Alberto D’Angelo, Valeria Emma Palmieri, Benedetta Panella, Roberto Petrioli, Anna Ianza, Stefania Nobili, Enrico Mini and Monica Ramello
DOI: 10.2174/1568009620999200918122426

Tumor-Induced Metabolism and T Cells Located in Tumor Environment

Volume:20   Issue:10
Pp: 741-756
Sara Iranparast, Sanaz Tayebi, Fatemeh Ahmadpour and Bahman Yousefi*
DOI: 10.2174/1568009620666200720010647

Selinexor (KPT-330), an Oral Selective Inhibitor of Nuclear Export (SINE) Compound, in Combination with FOLFOX in Patients with Metastatic Colorectal Cancer (mCRC) - Final Results of the Phase I Trial SENTINEL

Volume:20   Issue:10
Pp: 811-817
Sven Nilsson, Alexander Stein, Christian Rolfo, Anne L. Kranich, Julia Mann, Konstantinos Papadimitriou, Susann Theile, Stefanie Amberg and Carsten Bokemeyer*
DOI: 10.2174/1568009620666200628105727

Emerging Multi-cancer Regulatory Role of ESRP1: Orchestration of Alternative Splicing to Control EMT

Volume:20   Issue:9
Pp: 654-665
Yellamandayya Vadlamudi, Debasish K. Dey and Sun C. Kang*
DOI: 10.2174/1568009620666200621153831

Neoadjuvant Chemotherapy Induces the Appearance of New Copy Number Aberrations in Breast Tumor and is Associated with Metastasis

Volume:20   Issue:9
Pp: 681-688
Nikolai V. Litviakov*, Marina K. Ibragimova, Matvey M. Tsyganov, Artem V. Doroshenko, Eugeniy Y. Garbukov and Elena M. Slonimskaya
DOI: 10.2174/1568009620666200506104523