Current Cancer Drug Targets

CDK12 Promotes Breast Cancer Progression and Maintains Stemness by Activating c-myc/β -catenin Signaling

Volume: 20   Issue: 2
Pp: 156-165
Fang Peng, Chuansheng Yang, Yanan Kong, Xiaojia Huang, Yanyu Chen, Yangfan Zhou, Xinhua Xie* and Peng Liu*
DOI: 10.2174/1568009619666191118113220

COVID-19 Pandemic: Experiences in China and Implications for its Prevention and Treatment Worldwide

Volume: 20   Issue: 6
Pp: 410-416
Ning-Ning Liu*, Jing-Cong Tan, Jingquan Li, Shenghui Li*, Yong Cai* and Hui Wang*
DOI: 10.2174/1568009620666200414151419

Immune Checkpoint Inhibitors in AML-A New Frontier

Volume: 20   Issue: 7
Pp: 545-557
Rohit Thummalapalli, Hanna A. Knaus, Ivana Gojo and Joshua F. Zeidner*
DOI: 10.2174/1568009620666200421081455

Immune Checkpoint Inhibitors in Patients with Recurrent Hepatocellular Carcinoma after Liver Transplantation: A Case Report and Literature Review

Volume: 20   Issue: 9
Pp: 720-727
Jianguo Qiu, Wei Tang and Chengyou Du*
DOI: 10.2174/1568009620666200520084415

VS-5584 Inhibits Human Osteosarcoma Cells Growth by Induction of G1- phase Arrest through Regulating PI3K/mTOR and MAPK Pathways

Volume: 20   Issue: 8
Pp: 616-623
Jing-Yi Sun, Ya-Jun Hou, Hai-Juan Cui, Cheng Zhang, Ming-Feng Yang, Feng-Ze Wang, Zheng Sun, Cun-Dong Fan*, Bao-Liang Sun* and Jin Rok Oh*
DOI: 10.2174/1568009620666200414150353

Targeting IDH Mutations in AML: Wielding the Double-edged Sword of Differentiation

Volume: 20   Issue: 7
Pp: 490-500
Justin S. Becker and Amir T. Fathi*
DOI: 10.2174/1568009620666200424145622

Clinical Outcomes and Safety of Patients Treated with NAb-Paclitaxel Plus Gemcitabine in Metastatic Pancreatic Cancer: The NAPA Study

Volume: 20   Issue: 11
Pp: 887-895
Martina Catalano, Giandomenico Roviello*, Raffaele Conca, Alberto D’Angelo, Valeria Emma Palmieri, Benedetta Panella, Roberto Petrioli, Anna Ianza, Stefania Nobili, Enrico Mini and Monica Ramello
DOI: 10.2174/1568009620999200918122426

The Evolving AML Genomic Landscape: Therapeutic Implications

Volume: 20   Issue: 7
Pp: 532-544
Sachi Horibata*, George Alyateem, Christin B. DeStefano and Michael M. Gottesman*
DOI: 10.2174/1568009620666200424150321

Strategic Combination Therapies for Ovarian Cancer

Volume: 20   Issue: 8
Pp: 573-585
Xinran Li, Angel S.N. Ng, Victor C.Y. Mak, Karen K.L. Chan, Annie N.Y. Cheung and Lydia W.T. Cheung*
DOI: 10.2174/1568009620666200511084007

FLT3 Inhibition in Acute Myeloid Leukaemia – Current Knowledge and Future Prospects

Volume: 20   Issue: 7
Pp: 513-531
Francesca L. Hogan, Victoria Williams and Steven Knapper*
DOI: 10.2174/1570163817666200518075820

Targeted Drug Therapy to Overcome Chemoresistance in Triple-negative Breast Cancer

Volume: 20   Issue: 8
Pp: 559-572
Mamta Kumari, Praveen Thaggikuppe Krishnamurthy* and Piyong Sola
DOI: 10.2174/1568009620666200506110850

Targeting Different Pathways Using Novel Combination Therapy in Triple Negative Breast Cancer

Volume: 20   Issue: 8
Pp: 586-602
Manzoor A. Mir*, Hina Qayoom, Umar Mehraj, Safura Nisar, Basharat Bhat and Nissar A. Wani*
DOI: 10.2174/1570163817666200518081955

Hepatitis C Virus Infection and Treatment as Independent Prognostic Factors in Diffuse Large B-Cell Lymphoma Egyptian Patients

Volume: 20   Issue: 8
Pp: 638-645
Tamer A. Elbedewy, Hossam Eldin A. Elashtokhy, Sherief Abd-Elsalam* and Marwa A. Suliman
DOI: 10.2174/1568009620666200511084731

Exosome as a Natural Gene Delivery Vector for Cancer Treatment

Volume: 20   Issue: 11
Pp: 821-830
Prasad Pofali, Adrita Mondal and Vaishali Londhe*
DOI: 10.2174/1568009620666200924154149

Targeting Six Hallmarks of Cancer in Ovarian Cancer Therapy

Volume: 20   Issue: 11
Pp: 853-867
Han Gong, Dan Nie and Zhengyu Li*
DOI: 10.2174/1568009620999200816130218

Nanomedicine: A Promising Avenue for the Development of Effective Therapy for Breast Cancer

Volume: 20   Issue: 8
Pp: 603-615
Ali Sartaj, Sanjula Baboota and Javed Ali*
DOI: 10.2174/1568009620666200331124113

Vaccine and Cell-based Therapeutic Approaches in Acute Myeloid Leukemia

Volume: 20   Issue: 7
Pp: 473-489
Vaibhav Agrawal*, Olumide B. Gbolahan, Maximilian Stahl, Amer M. Zeidan, Mohammad Abu Zaid, Sherif S. Farag and Heiko Konig*
DOI: 10.2174/1568009620666200502011059

Identification of WDFY3 Neoantigens as Prognostic Markers in Longterm Survivors of Extrahepatic Cholangiocarcinoma

Volume: 20   Issue: 11
Pp: 875-886
Yingyi Wang, Bao Jin, Na Zhou, Zhao Sun, Jiayi Li, Qiao Chen, Xiangan Wu, Yi Zhou, Yue Shi, Xin Lu, Xinting Sang, Yilei Mao, Shunda Du*, Wenze Wang* and Chunmei Bai*
DOI: 10.2174/1568009620999200918121456

Overexpression of p62 Induces Autophagy and Promotes Proliferation, Migration and Invasion of Nasopharyngeal Carcinoma Cells through Promoting ERK Signaling Pathway

Volume: 20   Issue: 8
Pp: 624-637
Qiong Wu, Manlin Xiang, Kun Wang, Zhen Chen, Lu Long, Ya Tao, Yunlai Liang, Yahui Yan, Zhiqiang Xiao, Shiyang Qiu and Bin Yi*
DOI: 10.2174/1568009620666200424145122