Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204

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Most Accessed Articles

COVID-19 Pandemic: Experiences in China and Implications for its Prevention and Treatment Worldwide promotion: free to download

Volume: 20   Issue: 6
Pp: 410-416
Ning-Ning Liu*, Jing-Cong Tan, Jingquan Li, Shenghui Li*, Yong Cai* and Hui Wang*
DOI: 10.2174/1568009620666200414151419

C-Myc Signaling Pathway in Treatment and Prevention of Brain Tumors

Volume: 21   Issue: 1
Pp: 2-20
Milad Ashrafizadeh, Ali Zarabi, Kiavash Hushmandi, Ebrahim Rahmani Moghadam, Farid Hashemi, Salman Daneshi, Fardin Hashemi, Shima Tavakol, Reza Mohammadinejad, Masoud Najafi*, Namrata Dudha and Manoj Garg*
DOI: 10.2174/1568009620666201016121005

CDK12 Promotes Breast Cancer Progression and Maintains Stemness by Activating c-myc/β -catenin Signaling

Volume: 20   Issue: 2
Pp: 156-165
Fang Peng, Chuansheng Yang, Yanan Kong, Xiaojia Huang, Yanyu Chen, Yangfan Zhou, Xinhua Xie* and Peng Liu*
DOI: 10.2174/1568009619666191118113220

Clinical Outcomes and Safety of Patients Treated with NAb-Paclitaxel Plus Gemcitabine in Metastatic Pancreatic Cancer: The NAPA Study

Volume: 20   Issue: 11
Pp: 887-895
Martina Catalano, Giandomenico Roviello*, Raffaele Conca, Alberto D’Angelo, Valeria Emma Palmieri, Benedetta Panella, Roberto Petrioli, Anna Ianza, Stefania Nobili, Enrico Mini and Monica Ramello
DOI: 10.2174/1568009620999200918122426

Tyrosine Kinase Inhibitors (TKIs) in Lung Cancer Treatment: A Comprehensive Analysis

Volume: 21   Issue: 1
Pp: 55-69
Sivakumar Murugesan, Jayakumar Murugesan, Seedevi Palaniappan , Sivasankar Palaniappan, Tamilselvi Murugan, Shahid S. Siddiqui and Sivakumar Loganathan*
DOI: 10.2174/1568009620666201009130008

Identification of WDFY3 Neoantigens as Prognostic Markers in Longterm Survivors of Extrahepatic Cholangiocarcinoma

Volume: 20   Issue: 11
Pp: 875-886
Yingyi Wang, Bao Jin, Na Zhou, Zhao Sun, Jiayi Li, Qiao Chen, Xiangan Wu, Yi Zhou, Yue Shi, Xin Lu, Xinting Sang, Yilei Mao, Shunda Du*, Wenze Wang* and Chunmei Bai*
DOI: 10.2174/1568009620999200918121456

PROTACs: Promising Approaches for Epigenetic Strategies to Overcome Drug Resistance

Volume: 21   Issue: 4
Pp: 306-325
Sarah F. Giardina*, Elena Valdambrini, J. David Warren and Francis Barany
DOI: 10.2174/1568009621666210203110857

Tumor Penetrating Peptide-Functionalized Tenascin-C Antibody for Glioblastoma Targeting

Volume: 21   Issue: 1
Pp: 70-79
Prakash Lingasamy, Anett-Hildegard Laarmann and Tambet Teesalu *
DOI: 10.2174/1568009620666201001112749

Targeted Biological Effect of An Affitoxin Composed of an HPV16E7 Affibody Fused with Granzyme B (ZHPV16E7-GrB) Against Cervical Cancer In vitro and In vivo

Volume: 21   Issue: 3
Pp: 232-243
Wenhuan Wang, Xiaochun Tan, Jie Jiang, Yiqi Cai, Fangfang Feng, Lifang Zhang* and Wenshu Li*
DOI: 10.2174/1568009620666201207145720

Immunotherapy: A Potential Approach to Targeting Cancer Stem Cells

Volume: 21   Issue: 2
Pp: 117-131
Wenjun Wang, Ling Bai, Dongsheng Xu, Wei Li and Jiuwei Cui*
DOI: 10.2174/1568009620666200504111914

Management of Prostate Cancer with Systemic Therapy: A Prostate Cancer Unit Perspective

Volume: 21   Issue: 2
Pp: 107-116
Fabio Campodonico*, Marco Ennas, Silvia Zanardi , Ekaterini Zigoura, Arnoldo Piccardo, Luca Foppiani, Concetta Schiavone, Lino Squillace, Andrea Benelli, Andrea De Censi , Filippo Grillo-Ruggieri and Carlo Introini
DOI: 10.2174/1568009620666201021163919

MUC Glycoproteins: Potential Biomarkers and Molecular Targets for Cancer Therapy

Volume: 21   Issue: 2
Pp: 132-152
Chameli Ratan, Dalia Cicily K. D, Bhagyalakshmi Nair and Lekshmi. R. Nath*
DOI: 10.2174/1568009620666201116113334

Re-Sensitizing Tumor Cells to Cancer Drugs with Epigenetic Regulators

Volume: 21   Issue: 4
Pp: 353-359
Stefanie Rauscher, Richard Greil and Roland Geisberger*
DOI: 10.2174/1568009620666210108102723

Paclitaxel Priming of TRAIL Expressing Mesenchymal Stromal Cells (MSCs- TRAIL) Increases Antitumor Efficacy of Their Secretome

Volume: 21   Issue: 3
Pp: 213-222
Valentina Coccè, Arianna Bonomi, Loredana Cavicchini, Francesca Sisto, Aldo Giannì, Giampietro Farronato, Giulio Alessandri, Francesco Petrella, Valeria Sordi, Eugenio Parati, Gianpietro Bondiolotti, Francesca Paino and Augusto Pessina*
DOI: 10.2174/1568009620666201116112153

Novel MicroRNA Binding Site SNPs and the Risk of Clear Cell Renal Cell Carcinoma (ccRCC): A Case-Control Study

Volume: 21   Issue: 3
Pp: 203-212
Irina R. Gilyazova, Narasimha M. Beeraka, Elizaveta A. Klimentova, Kirill V. Bulygin, Vladimir N. Nikolenko, Adel A. Izmailov, Gulshat R. Gilyazova, Valentin N. Pavlov, Elsa K. Khusnutdinova, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*
DOI: 10.2174/1568009620666201120151226

Selinexor (KPT-330), an Oral Selective Inhibitor of Nuclear Export (SINE) Compound, in Combination with FOLFOX in Patients with Metastatic Colorectal Cancer (mCRC) - Final Results of the Phase I Trial SENTINEL

Volume: 20   Issue: 10
Pp: 811-817
Sven Nilsson, Alexander Stein, Christian Rolfo, Anne L. Kranich, Julia Mann, Konstantinos Papadimitriou, Susann Theile, Stefanie Amberg and Carsten Bokemeyer*
DOI: 10.2174/1568009620666200628105727

Concomitant Expression of Inhibitory Molecules for T cell Activation Predicts Poor Survival in Patients with Esophageal Squamous Cell Carcinoma

Volume: 21   Issue: 3
Pp: 244-253
Zhijun Chen, Kexin Cao, Jinghang Zhang, Zhuangzhuang Liu, Liaoxun Lu, Bo Qi, Lijin Shi, Rong Huang* and Song Zhao*
DOI: 10.2174/1568009620666201120152333