Current Cancer Drug Targets

Editor-in-Chief

Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204
(USA)

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Volume: 3 Issue: 5, October

Preface [Hot topic:Hsp90 Molecular Chaperone Inhibitors: Opportunities and Challenges (Guest Editor: Paul Workman)]

Volume:3   Issue: 5
Pp: i-i
Paul Workman
DOI: 10.2174/1568009033481840
Published on: 01 March, 2012

Overview: Translating Hsp90 Biology into Hsp90 Drugs

Volume:3   Issue: 5
Pp: 297-300
Paul Workman
DOI: 10.2174/1568009033481868
Published on: 01 March, 2012

Structure and Functional Relationships of Hsp90

Volume:3   Issue: 5
Pp: 301-323
Chrisostomos Prodromou and Laurence H. Pearl
DOI: 10.2174/1568009033481877
Published on: 01 March, 2012

Natural Product Origins of Hsp90 Inhibitors

Volume:3   Issue: 5
Pp: 325-330
Yoshimasa Uehara
DOI: 10.2174/1568009033481796
Published on: 01 March, 2012

Genes and Proteins Governing the Cellular Sensitivity to HSP90 Inhibitors: A Mechanistic Perspective

Volume:3   Issue: 5
Pp: 331-341
Alison Maloney, Paul A. Clarke and Paul Workman
DOI: 10.2174/1568009033481822
Published on: 01 March, 2012

The C-Terminal Half of Heat Shock Protein 90 Represents a Second Site for Pharmacologic Intervention in Chaperone Function

Volume:3   Issue: 5
Pp: 343-347
Monica G. Marcu and Leonard M. Neckers
DOI: 10.2174/1568009033481804
Published on: 01 March, 2012

The Stress Response: Implications for the Clinical Development of Hsp90 Inhibitors

Volume:3   Issue: 5
Pp: 349-358
Luke Whitesell, Rochelle Bagatell and Ryan Falsey
DOI: 10.2174/1568009033481787
Published on: 01 March, 2012

Development of Radicicol Analogues

Volume:3   Issue: 5
Pp: 359-369
Shiro Soga, Yukimasa Shiotsu, Shiro Akinaga and Sreenath V. Sharma
DOI: 10.2174/1568009033481859
Published on: 01 March, 2012

Development of Purine-Scaffold Small Molecule Inhibitors of Hsp90

Volume:3   Issue: 5
Pp: 371-376
Gabriela Chiosis, Brian Lucas, Henri Huezo, David Solit, Andrea Basso and Neal Rosen
DOI: 10.2174/1568009033481778
Published on: 01 March, 2012

Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin

Volume:3   Issue: 5
Pp: 377-383
Edward A. Sausville, Joseph E. Tomaszewski and Percy Ivy
DOI: 10.2174/1568009033481831
Published on: 01 March, 2012

The Clinical Applications of Heat Shock Protein Inhibitors in Cancer - Present and Future

Volume:3   Issue: 5
Pp: 385-390
Udai Banerji, Ian Judson and Paul Workman
DOI: 10.2174/1568009033481813
Published on: 01 March, 2012