Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204

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Volume: 21 Issue: 3, March 2021

Acid Ceramidase, a Double-edged Sword in Cancer Aggression: A Minireview

Volume:21   Issue: 3
Pp: 177-191
Helen Shiphrah Vethakanraj, Niveditha Chandrasekaran and Ashok Kumar Sekar*
DOI: 10.2174/1568009620666201223154621
Published on: 23 December, 2020

MALAT1 as a Versatile Regulator of Cancer: Overview of the Updates from Predatory Role as Competitive Endogenous RNA to Mechanistic Insights

Volume:21   Issue: 3
Pp: 192-202
Ammad Ahmad Farooqi*, Evangelia Legaki, Maria Gazouli, Silvia Rinaldi and Rossana Berardi
DOI: 10.2174/1568009620999200730183110
Published on: 30 July, 2020

Novel MicroRNA Binding Site SNPs and the Risk of Clear Cell Renal Cell Carcinoma (ccRCC): A Case-Control Study

Volume:21   Issue: 3
Pp: 203-212
Irina R. Gilyazova, Narasimha M. Beeraka, Elizaveta A. Klimentova, Kirill V. Bulygin, Vladimir N. Nikolenko, Adel A. Izmailov, Gulshat R. Gilyazova, Valentin N. Pavlov, Elsa K. Khusnutdinova, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*
DOI: 10.2174/1568009620666201120151226
Published on: 20 November, 2020

Paclitaxel Priming of TRAIL Expressing Mesenchymal Stromal Cells (MSCs- TRAIL) Increases Antitumor Efficacy of Their Secretome

Volume:21   Issue: 3
Pp: 213-222
Valentina Coccè, Arianna Bonomi, Loredana Cavicchini, Francesca Sisto, Aldo Giannì, Giampietro Farronato, Giulio Alessandri, Francesco Petrella, Valeria Sordi, Eugenio Parati, Gianpietro Bondiolotti, Francesca Paino and Augusto Pessina*
DOI: 10.2174/1568009620666201116112153
Published on: 15 November, 2020

Selective Antitumor Effect of Shikonin Derived DMAKO-20 on Melanoma through CYP1B1

Volume:21   Issue: 3
Pp: 223-231
Junqi Cui, Xiaobo Zhou, Jia Huang, Jiahua Cui* and Jun Chen*
DOI: 10.2174/1568009620666201116112937
Published on: 15 November, 2020

Targeted Biological Effect of An Affitoxin Composed of an HPV16E7 Affibody Fused with Granzyme B (ZHPV16E7-GrB) Against Cervical Cancer In vitro and In vivo

Volume:21   Issue: 3
Pp: 232-243
Wenhuan Wang, Xiaochun Tan, Jie Jiang, Yiqi Cai, Fangfang Feng, Lifang Zhang* and Wenshu Li*
DOI: 10.2174/1568009620666201207145720
Published on: 07 December, 2020

Concomitant Expression of Inhibitory Molecules for T cell Activation Predicts Poor Survival in Patients with Esophageal Squamous Cell Carcinoma

Volume:21   Issue: 3
Pp: 244-253
Zhijun Chen, Kexin Cao, Jinghang Zhang, Zhuangzhuang Liu, Liaoxun Lu, Bo Qi, Lijin Shi, Rong Huang* and Song Zhao*
DOI: 10.2174/1568009620666201120152333
Published on: 20 November, 2020

Forkhead-box A3 (FOXA3) Represses Cancer Stemness and Partially Potentiates Chemosensitivity by Targeting Metastasis-Associated in Colon Cancer 1 (MACC1) Signaling Pathway in Colorectal Cancer Cells

Volume:21   Issue: 3
Pp: 254-267
Na Li*, Yun Li, Hongbo Gao, Jing Li, Xiaoping Ma, Xiaomei Liu, Ping Gong, Xiaobin Cui and Yong Li*
DOI: 10.2174/1568009620666201207150632
Published on: 07 December, 2020