Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204

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Volume: 13 Issue: 6, July 2013

Jaridonin, a Novel Ent-Kaurene Diterpenoid from Isodon rubescens, Inducing Apoptosis via Production of Reactive Oxygen Species in Esophageal Cancer Cells

Volume:13   Issue: 6
Pp: 611-624
Yong-Cheng Ma, Yu Ke, Xiaolin Zi, Wen Zhao, Xiao-Jing Shi and Hong-Min Liu
DOI: 10.2174/15680096113139990030
Published on: 27 June, 2013

Hydroxytyrosol Promotes Superoxide Production and Defects in Autophagy Leading to Anti-proliferation and Apoptosis on Human Prostate Cancer Cells

Volume:13   Issue: 6
Pp: 625-639
Cheng Luo, Yan Li, Hui Wang, Yang Cui, Zhihui Feng, Hua Li, Yuan Li, Ying Wang, Karin Wurtz, Peter Weber, Jiangang Long and Jiankang Liu
DOI: 10.2174/15680096113139990035
Published on: 27 June, 2013

Autophagy Fails to Alter Withaferin A-Mediated Lethality in Human Breast Cancer Cells

Volume:13   Issue: 6
Pp: 640-650
Eun-Ryeong Hahm and Shivendra V. Singh
DOI: 10.2174/15680096113139990039
Published on: 27 June, 2013

Identification of the ZAK-MKK4-JNK-TGFβ Signaling Pathway as a Molecular Target for Novel Synthetic Iminoquinone Anticancer Compound BA-TPQ

Volume:13   Issue: 6
Pp: 651-660
Deng Chen, Wei Wang, Jiang-Jiang Qin, Ming-Hai Wang, Srinivasan Murugesan, Dwayaja H. Nadkarni, Sadanandan E. Velu, Hui Wang and Ruiwen Zhang
DOI: 10.2174/15680096113139990040
Published on: 27 June, 2013

Optimizing Outcomes Following Allogeneic Hematopoietic Progenitor Cell Transplantation in AML: The Role of Hypomethylating Agents

Volume:13   Issue: 6
Pp: 661-669
Massimo Martino, Roberta Fedele, Tiziana Moscato and Francesca Ronco
DOI: 10.2174/15680096113139990005
Published on: 27 June, 2013

Targeting Hypoxia for Sensitization of Tumors to Radio- and Chemotherapy open access plus

Volume:13   Issue: 6
Pp: 670-685
Khaled Ghattass, Rana Assah, Marwan El-Sabban and Hala Gali-Muhtasib
DOI: 10.2174/15680096113139990004
Published on: 27 June, 2013

Oncogenic Variant RON160 Expression in Breast Cancer and its Potential as a Therapeutic Target by Small Molecule Tyrosine Kinase Inhibitor

Volume:13   Issue: 6
Pp: 686-697
Hang-Ping Yao, Chun-Mei Zhuang, Yong-Qing Zhou, Jun-Ying Zeng, Rui-Wen Zhang and Ming-Hai Wang
DOI: 10.2174/15680096113139990038
Published on: 27 June, 2013

Unmet Needs in Ovarian Cancer: Dividing Histologic Subtypes to Exploit Novel Targets and Pathways open access plus

Volume:13   Issue: 6
Pp: 698-707
Vijaya Galic, Robert L. Coleman and Thomas J. Herzog
DOI: 10.2174/15680096113139990002
Published on: 27 June, 2013