Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204

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Volume: 12 Issue: 6, July 2012

Pioglitazone Prevents Smoking Carcinogen-Induced Lung Tumor Development in Mice

Volume:12   Issue: 6
Pp: 597-606
M. -Y. Li, A. W.Y. Kong, H. Yuan, L. T. Ma, M. K.Y. Hsin, I. Y.P. Wan, M. J. Underwood and G. G. Chen
DOI: 10.2174/156800912801784848
Published on: 28 May, 2012

Cyclooxygenase-2 (COX-2) Mediates Arsenite Inhibition of UVB-Induced Cellular Apoptosis in Mouse Epidermal Cl41 Cells

Volume:12   Issue: 6
Pp: 607-616
Z. Zuo, W. Ouyang, J. Li, M. Costa and C. Huang
DOI: 10.2174/156800912801784802
Published on: 28 May, 2012

Acid Ceramidase as a Chemotherapeutic Target to Overcome Resistance to the Antitumoral Effect of Choline Kinase α Inhibition

Volume:12   Issue: 6
Pp: 617-624
A. Ramirez de Molina, A. de la Cueva, R. Machado-Pinilla, V. Rodriguez-Fanjul, T. Gomez del Pulgar, A. Cebrian, R. Perona and J. C. Lacal
DOI: 10.2174/156800912801784811
Published on: 28 May, 2012

Growth Suppression and Mitotic Defect Induced by JNJ-7706621, an Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases

Volume:12   Issue: 6
Pp: 625-639
A. Matsuhashi, T. Ohno, M. Kimura, A. Hara, M. Saio, A. Nagano, G. Kawai, M. Saitou, I. Takigami, K. Yamada, Y. Okano and K. Shimizu
DOI: 10.2174/156800912801784839
Published on: 28 May, 2012

Lycopene Modulation of Molecular Targets Affected by Smoking Exposure

Volume:12   Issue: 6
Pp: 640-657
P. Palozza, R. Simone, A. Catalano, M. Russo and V. Bohm
DOI: 10.2174/156800912801784866
Published on: 28 May, 2012

Structural Comparison of the Interaction of Tubulin with Various Ligands Affecting Microtubule Dynamics

Volume:12   Issue: 6
Pp: 658-666
E. Stec-Martyna, M. Ponassi, M. Miele, S. Parodi, L. Felli and C. Rosano
DOI: 10.2174/156800912801784893
Published on: 28 May, 2012

Inhibition of Protein N-Myristoylation: A Therapeutic Protocol in Developing Anticancer Agents

Volume:12   Issue: 6
Pp: 667-692
U. Das, S. Kumar, J. R. Dimmock and R. K. Sharma
DOI: 10.2174/156800912801784857
Published on: 28 May, 2012

High CXCR4 Expression Correlates with Sunitinib Poor Response in Metastatic Renal Cancer open access plus

Volume:12   Issue: 6
Pp: 693-702
C. D'Alterio, L. Portella, A. Ottaiano, M. Rizzo, G. Carteni, S. Pignata, G. Facchini, S. Perdona, G. Di Lorenzo, R. Autorino, R. Franco, A. La Mura, O. Nappi, G. Castello and S. Scala
DOI: 10.2174/156800912801784820
Published on: 28 May, 2012

Increased Expression of Matrix Metalloproteinases Mediates Thromboxane A2-Induced Invasion in Lung Cancer Cells

Volume:12   Issue: 6
Pp: 703-715
Xiuling Li and Hsin-Hsiung Tai
DOI: 10.2174/156800912801784884
Published on: 28 May, 2012

Emerging Roles for Modulation of microRNA Signatures in Cancer Chemoprevention open access plus

Volume:12   Issue: 6
Pp: 716-740
K. Neelakandan, P. Babu and S. Nair
DOI: 10.2174/156800912801784875
Published on: 28 May, 2012