Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204

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Volume: 12 Issue: 4, May 2012

EDITORIAL [Hot Topic: Molecularly Targeted Treatments for Colorectal Cancer: Advances and Limitations (Guest Editor: Silvio Parodi)]

Volume:12   Issue: 4
Pp: 301-302
Silvio Parodi
DOI: 10.2174/156800912800190947
Published on: 04 April, 2012

Role of Angiogenesis Inhibitors in Colorectal Cancer: Sensitive and Insensitive Tumors

Volume:12   Issue: 4
Pp: 303-315
L. Bagnasco, D. Piras, S. Parodi, I. Bauer, G. Zoppoli, F. Patrone and A. Ballestrero
DOI: 10.2174/156800912800190929
Published on: 04 April, 2012

Patient-Tailored Treatments with Anti-EGFR Monoclonal Antibodies in Advanced Colorectal Cancer: KRAS and Beyond

Volume:12   Issue: 4
Pp: 316-328
A. Ballestrero, A. Garuti, G. Cirmena, I. Rocco, C. Palermo, A. Nencioni, S. Scabini, G. Zoppoli, S. Parodi and F. Patrone
DOI: 10.2174/156800912800190956
Published on: 04 April, 2012

Synthetic Lethality-Based Therapeutics: Perspectives for Applications in Colorectal Cancer

Volume:12   Issue: 4
Pp: 329-338
D. Soncini, I. Caffa, F. Patrone, A. Ballestrero and A. Nencioni
DOI: 10.2174/156800912800190938
Published on: 04 April, 2012

A Multi-Scale Approach to Colorectal Cancer: From a Biochemical- Interaction Signaling-Network Level, to Multi-Cellular Dynamics of Malignant Transformation. Interplay with Mutations and Onco-Protein Inhibitor Drugs

Volume:12   Issue: 4
Pp: 339-355
L. Tortolina, N. Castagnino, C. De Ambrosi, E. Moran, F. Patrone, A. Ballestrero and S. Parodi
DOI: 10.2174/156800912800190910
Published on: 04 April, 2012

DNA Damage Response Pathways and Cell Cycle Checkpoints in Colorectal Cancer: Current Concepts and Future Perspectives for Targeted Treatment

Volume:12   Issue: 4
Pp: 356-371
S. Solier, Y. -W. Zhang, A. Ballestrero, Y. Pommier and G. Zoppoli
DOI: 10.2174/156800912800190901
Published on: 04 April, 2012

Clinical Experience with Thalidomide and Lenalidomide in Multiple Myeloma

Volume:12   Issue: 4
Pp: 372-390
T. Moehler
DOI: 10.2174/156800912800190893
Published on: 04 April, 2012

Genetic Variants in Genes Involved in Mechanisms of Chemoresistance to Anticancer Drugs open access plus

Volume:12   Issue: 4
Pp: 402-438
J. J.G. Marin, O. Briz, M. J. Monte, A. G. Blazquez and R. I.R. Macias
DOI: 10.2174/156800912800190875
Published on: 04 April, 2012

An Epigenetic Approach to Pancreatic Cancer Treatment: The Prospective Role of Histone Deacetylase Inhibitors open access plus

Volume:12   Issue: 4
Pp: 439-452
Nicola Tinari, Michele De Tursi, Antonino Grassadonia, Marinella Zilli, Liborio Stuppia, Stefano Iacobelli and Clara Natoli
DOI: 10.2174/156800912800190884
Published on: 04 April, 2012