Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204

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The Cyclin-Dependent Kinase Inhibitor p21CDKN1A as a Target of Anti-Cancer Drugs

Volume:12   Issue: 2
Pp: 85-96
L. A. Stivala, O. Cazzalini and E. Prosperi
DOI: 10.2174/156800912799095126

Gamma-Amino Butyric Acid Inhibits the Nicotine-Imposed Stimulatory Challenge in Xenograft Models of Non-Small Cell Lung Carcinoma

Volume:12   Issue: 2
Pp: 97-106
H. A.N. Al-Wadei, M. H. Al-Wadei, M. F. Ullah and H. M. Schuller
DOI: 10.2174/156800912799095171

Adding to the Mix: Fibroblast Growth Factor and Platelet-Derived Growth Factor Receptor Pathways as Targets in Non – small Cell Lung Cancer open access plus

Volume:12   Issue: 2
Pp: 107-123
S. A. Kono, L. E. Heasley, R. C. Doebele and D. R. Camidge
DOI: 10.2174/156800912799095144

Analysis of the Concordance in the EGFR Pathway Status Between Primary Tumors and Related Metastases of Colorectal Cancer Patients:Implications for Cancer Therapy

Volume:12   Issue: 2
Pp: 124-131
P. Cejas, M. Lopez-Gomez, C. Aguayo, R. Madero, J. Moreno-Rubio, J. de Castro Carpeno, C. Belda-Iniesta, J. Barriuso, V. Moreno Garcia, E. Diaz, E. Burgos, M. Gonzalez-Baron and J. Feliu
DOI: 10.2174/156800912799095162

Characterization of the Prostaglandin E2 Pathway in a Rat Model of Esophageal Adenocarcinoma

Volume:12   Issue: 2
Pp: 132-143
E. Piazuelo, S. Santander, C. Cebrian, P. Jimenez, C. Pastor, M. A. Garcia-Gonzalez, F. Esteva, P. Esquivias, J. Ortego and A. Lanas
DOI: 10.2174/156800912799095199

Transplacental Antioxidants Inhibit Lung Tumors in Mice Exposed to Cigarette Smoke After Birth: A Novel Preventative Strategy?

Volume:12   Issue: 2
Pp: 164-169
R. Balansky, G. Ganchev, M. Iltcheva, V. E. Steele and S. De Flora
DOI: 10.2174/156800912799095153

Anticancer Drugs Aimed at E6 and E7 Activity in HPV-Positive Cervical Cancer open access plus

Volume:12   Issue: 2
Pp: 170-184
S. Tan, E. G.E. de Vries, A. G.J. van der Zee and S. de Jong
DOI: 10.2174/156800912799095135