Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204

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Volume: 11 Issue: 8, October

The Phosphoinositide 3-Kinase Signaling Pathway as a Therapeutic Target in Grade IV Brain Tumors

Volume:11   Issue: 8
Pp: 894-918
K. Holand, F. Salm and A. Arcaro
DOI: 10.2174/156800911797264743
Published on: 01 March, 2012

Pharmacological Characterization of Histone Deacetylase Inhibitor and Tumor Cell-Growth Inhibition Properties of New Benzofuranone Compounds

Volume:11   Issue: 8
Pp: 919-928
C. Blanquart, M. Francois, C. Charrier, P. Bertrand and M. Gregoire
DOI: 10.2174/156800911797264761
Published on: 01 March, 2012

L-Asparaginase and Inhibitors of Glutamine Synthetase Disclose Glutamine Addiction of β-Catenin-Mutated Human Hepatocellular Carcinoma Cells

Volume:11   Issue: 8
Pp: 929-943
S. Tardito, M. Chiu, J. Uggeri, F. Da Ros, A. Zerbini, V. Dall`Asta, G. Missale and O. Bussolati*
DOI: 10.2174/156800911797264725
Published on: 01 March, 2012

Comparing the Efficacy of Sunitinib with Sorafenib in Xenograft Models of Human Hepatocellular Carcinoma: Mechanistic Explanation

Volume:11   Issue: 8
Pp: 944-953
H. Huynh, S. P. Choo, H. C. Toh, W. M. Tai, A. Y.F. Chung, P. K.H. Chow, R. Ong and K. C. Soo
DOI: 10.2174/156800911797264716
Published on: 01 March, 2012

Active-Targeted Nanotherapy Strategies for Prostate Cancer

Volume:11   Issue: 8
Pp: 954-965
M. Katsogiannou, L. Peng, C. V. Catapano and P. Rocchi
DOI: 10.2174/156800911797264770
Published on: 01 March, 2012

H+-myo-Inositol Transporter SLC2A13 as a Potential Marker for Cancer Stem Cells in an Oral Squamous Cell Carcinoma

Volume:11   Issue: 8
Pp: 966-975
D. G. Lee, J.-H. Lee, B. K. Choi, M.-J. Kim, S.-M. Kim, K. S. Kim, K. Chang, S. H. Park, Y.-S. Bae and B. S. Kwon
DOI: 10.2174/156800911797264752
Published on: 01 March, 2012

RNAi Screening Identifies TAK1 as a Potential Target for the Enhanced Efficacy of Topoisomerase Inhibitors

Volume:11   Issue: 8
Pp: 976-986
S. E. Martin, Z.-H. Wu, K. Gehlhaus, T. L. Jones, Y.-W. Zhang, R. Guha, S. Miyamoto, Y. Pommier and N. J. Caplen
DOI: 10.2174/156800911797264734
Published on: 01 March, 2012

Reactivation of p53 by Inhibiting Mdm2 E3 Ligase: A Novel Antitumor Approach

Volume:11   Issue: 8
Pp: 987-994
J. Di, Y. Zhang and J. Zheng
DOI: 10.2174/156800911797264789
Published on: 01 March, 2012