Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204

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Volume: 11 Issue: 3, March

Editorial [Hot Topic: Targeting Tumor Uniquitin-Proteasome Pathway with New and Old Drugs (Guest Editor: Q. Ping Dou)]

Volume:11   Issue: 3
Pp: 236-238
Q. Ping Dou
DOI: 10.2174/156800911794519789
Published on: 01 March, 2012

Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives

Volume:11   Issue: 3
Pp: 239-253
D. Chen, M. Frezza, S. Schmitt, J. Kanwar and Q. P. Dou
DOI: 10.2174/156800911794519752
Published on: 01 March, 2012

Marizomib, a Proteasome Inhibitor for All Seasons: Preclinical Profile and a Framework for Clinical Trials

Volume:11   Issue: 3
Pp: 254-284
B. C. Potts, M. X. Albitar, K. C. Anderson, S. Baritaki, C. Berkers, B. Bonavida, J. Chandra, D. Chauhan, J. C. Cusack, W. Fenical, I. M. Ghobrial, M. Groll, P. R. Jensen, K. S. Lam, G. K. Lloyd, W. McBride, D. J. McConkey, C. P. Miller, S. T.C. Neuteboom, Y. Oki, H. Ovaa, F. Pajonk, P. G. Richardson, A. M. Roccaro, C. M. Sloss, M. A. Spear, E. Valashi, A. Younes and M. A. Palladino
DOI: 10.2174/156800911794519716
Published on: 01 March, 2012

Second Generation Proteasome Inhibitors: Carfilzomib and Immunoproteasome-Specific Inhibitors (IPSIs)

Volume:11   Issue: 3
Pp: 285-295
D. J. Kuhn, R. Z. Orlowski and C. C. Bjorklund
DOI: 10.2174/156800911794519725
Published on: 01 March, 2012

Green Tea Polyphenols as Proteasome Inhibitors: Implication in Chemoprevention

Volume:11   Issue: 3
Pp: 296-306
H. Yang, K. Landis-Piwowar, T. H. Chan and Q. P. Dou
DOI: 10.2174/156800911794519743
Published on: 01 March, 2012

Targeting Proteasomes with Naturally Occurring Compounds in Cancer Treatment

Volume:11   Issue: 3
Pp: 307-324
V. Cecarini, M. Cuccioloni, M. Mozzicafreddo, L. Bonfili, M. Angeletti and A. M. Eleuteri
DOI: 10.2174/156800911794519815
Published on: 01 March, 2012

Clioquinol – A Novel Copper-Dependent and Independent Proteasome Inhibitor

Volume:11   Issue: 3
Pp: 325-331
A. D. Schimmer
DOI: 10.2174/156800911794519770
Published on: 01 March, 2012

SCF E3 Ubiquitin Ligases as Anticancer Targets

Volume:11   Issue: 3
Pp: 347-356
L. Jia and Y. Sun
DOI: 10.2174/156800911794519734
Published on: 01 March, 2012

Autophagy: Molecular Mechanisms and their Implications for Anticancer Therapies

Volume:11   Issue: 3
Pp: 357-379
S. Meschini, M. Condello, P. Lista and G. Arancia
DOI: 10.2174/156800911794519707
Published on: 01 March, 2012

Peptidyl Prolyl Isomerase, Pin1 is a Potential Target for Enhancing the Therapeutic Efficacy of Etoposide

Volume:11   Issue: 3
Pp: 380-392
R. Mathur, S. Chandna, P. N. Kapoor and B. S. Dwarakanath
DOI: 10.2174/156800911794519761
Published on: 01 March, 2012