Current Cancer Drug Targets

Editor-in-Chief

Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204
(USA)

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Most Cited Article

Resveratrol as an Adjuvant for Normal Tissues Protection and Tumor Sensitization

Volume:20   Issue:2
Pp: 130-145
Keywan Mortezaee, Masoud Najafi*, Bagher Farhood*, Amirhossein Ahmadi*, Dheyauldeen Shabeeb and Ahmed E. Musa
DOI: 10.2174/1568009619666191019143539

Old and New Approaches to Target the Hsp90 Chaperone

Volume:20   Issue:4
Pp: 253-270
Jackee Sanchez, Trever R. Carter, Mark S. Cohen* and Brian S.J. Blagg
DOI: 10.2174/1568009619666191202101330

Natural DNA Intercalators as Promising Therapeutics for Cancer and Infectious Diseases

Volume:20   Issue:1
Pp: 19-32
Martyna Godzieba* and Slawomir Ciesielski
DOI: 10.2174/1568009619666191007112516

circEPSTI1 Acts as a ceRNA to Regulate the Progression of Osteosarcoma

Volume:20   Issue:4
Pp: 288-294
Xinyu Tan, Duxun Tan, Haomiao Li, Ye Lin, Zhishen Wen and Canjun Zeng*
DOI: 10.2174/1568009619666191107140948

COVID-19 Pandemic: Experiences in China and Implications for its Prevention and Treatment Worldwide

Volume:20   Issue:6
Pp: 410-416
Ning-Ning Liu*, Jing-Cong Tan, Jingquan Li, Shenghui Li*, Yong Cai* and Hui Wang*
DOI: 10.2174/1568009620666200414151419

Cancer Cell-derived Secretory Factors in Breast Cancer-associated Lung Metastasis: Their Mechanism and Future Prospects open access plus

Volume:20   Issue:3
Pp: 168-186
Tabinda Urooj*, Bushra Wasim, Shamim Mushtaq, Syed Nudrat Nawaid Shah and Muzna Shah
DOI: 10.2174/1568009620666191220151856

CDK12 Promotes Breast Cancer Progression and Maintains Stemness by Activating c-myc/β -catenin Signaling

Volume:20   Issue:2
Pp: 156-165
Fang Peng, Chuansheng Yang, Yanan Kong, Xiaojia Huang, Yanyu Chen, Yangfan Zhou, Xinhua Xie* and Peng Liu*
DOI: 10.2174/1568009619666191118113220

Effects of Intermittent Hypoxia on Expression of Glucose Metabolism Genes in MCF7 Breast Cancer Cell Line

Volume:20   Issue:3
Pp: 216-222
Yazun Jarrar, Malek Zihlif*, Abdel Qader Al Bawab and Ahmad Sharab
DOI: 10.2174/1568009619666191116095847

C/EBPα Regulates FOXC1 to Modulate Tumor Growth by Interacting with PPARγ in Hepatocellular Carcinoma

Volume:20   Issue:1
Pp: 59-66
Zhuo Xu, Shao-Hua Meng, Jian-Guo Bai, Chao Sun*, Li-Li Zhao*, Rui-Feng Tang, Zhao-Lin Yin, Jun-Wei Ji, Wei Yang and Guang-Jun Ma
DOI: 10.2174/1568009619666190912161003

HOTAIR Competitively Binds MiRNA330 as a Molecular Sponge to Increase the Resistance of Gastric Cancer to Trastuzumab

Volume:20   Issue:9
Pp: 700-709
Liangyu Bie, Suxia Luo*, Dan Li, Yan Wei, Yu Mu, Xiaobing Chen, Saiqi Wang, Ping Guo and Xiaoyu Lu
DOI: 10.2174/1568009620666200504114000

Overexpression of p62 Induces Autophagy and Promotes Proliferation, Migration and Invasion of Nasopharyngeal Carcinoma Cells through Promoting ERK Signaling Pathway

Volume:20   Issue:8
Pp: 624-637
Qiong Wu, Manlin Xiang, Kun Wang, Zhen Chen, Lu Long, Ya Tao, Yunlai Liang, Yahui Yan, Zhiqiang Xiao, Shiyang Qiu and Bin Yi*
DOI: 10.2174/1568009620666200424145122

CircRNA SCARB1 Promotes Renal Cell Carcinoma Progression Via Mir- 510-5p/SDC3 Axis

Volume:20   Issue:6
Pp: 461-470
Jijian Sun*, Shijie Pan, Hongquan Cui and Hao Li
DOI: 10.2174/1568009620666200409130032

Novel Homeodomain Transcription Factor Nkx2.2 in the Brain Tumor Development

Volume:20   Issue:5
Pp: 335-340
Mubeena P.M. Mariyath, Mehdi H. Shahi*, Shirin Farheen, Mohd Tayyab, Nabeela Khanam and Asif Ali
DOI: 10.2174/1568009618666180102111539

Exosome as a Natural Gene Delivery Vector for Cancer Treatment

Volume:20   Issue:11
Pp: 821-830
Prasad Pofali, Adrita Mondal and Vaishali Londhe*
DOI: 10.2174/1568009620666200924154149

Emerging Multi-cancer Regulatory Role of ESRP1: Orchestration of Alternative Splicing to Control EMT

Volume:20   Issue:9
Pp: 654-665
Yellamandayya Vadlamudi, Debasish K. Dey and Sun C. Kang*
DOI: 10.2174/1568009620666200621153831

Targeting Different Pathways Using Novel Combination Therapy in Triple Negative Breast Cancer

Volume:20   Issue:8
Pp: 586-602
Manzoor A. Mir*, Hina Qayoom, Umar Mehraj, Safura Nisar, Basharat Bhat and Nissar A. Wani*
DOI: 10.2174/1570163817666200518081955

FLT3 Inhibition in Acute Myeloid Leukaemia – Current Knowledge and Future Prospects

Volume:20   Issue:7
Pp: 513-531
Francesca L. Hogan, Victoria Williams and Steven Knapper*
DOI: 10.2174/1570163817666200518075820

VS-5584 Inhibits Human Osteosarcoma Cells Growth by Induction of G1- phase Arrest through Regulating PI3K/mTOR and MAPK Pathways

Volume:20   Issue:8
Pp: 616-623
Jing-Yi Sun, Ya-Jun Hou, Hai-Juan Cui, Cheng Zhang, Ming-Feng Yang, Feng-Ze Wang, Zheng Sun, Cun-Dong Fan*, Bao-Liang Sun* and Jin Rok Oh*
DOI: 10.2174/1568009620666200414150353

Hypermethylation of Single CpG Dinucleotides at the Promoter of CXCL13 Gene Promoting Cell Migration in Cervical Cancer

Volume:20   Issue:5
Pp: 355-363
Dong Ma , Shao-Bei Fan , Na Hua, Guo-Hua Li, Quan Chang and Xiao Liu *
DOI: 10.2174/1568009620666200102123635

Study of Toll-like Receptor 3 Gene Polymorphism as a Novel Risk Factor for HCV-related Hepatocellular Carcinoma in Egypt

Volume:20   Issue:5
Pp: 382-389
Shimaa EL-Sharawy, Osama El- Sayed Negm, Sherief Abd-Elsalam*, Hesham Ahmed EL-Sorogy and Mona Ahmed Helmy Shehata
DOI: 10.2174/1568009620666200319102929

Disintegrin Tablysin-15 Suppresses Cancer Hallmarks in Melanoma Cells by Blocking FAK/Akt/ERK and NF-κB Signaling

Volume:20   Issue:4
Pp: 306-315
Zhenhui Deng, Qingye Zeng, Jinwei Chai, Bei Zhang, Wenhong Zheng, Xueqing Xu* and Jiguo Wu*
DOI: 10.2174/1568009620666200101094736