Abstract
The preparation of steroids containing oxygenated functions in suitable positions of the steroid nucleus is of great importance and can be achieved by means of several oxidative processes. In this paper allylic oxidation, β-selective epoxidation, alcohol oxidation and remote functionalization reactions in steroid substrates are reviewed. Focus has been given to catalytic processes because of their major importance from the viewpoint of synthetic organic chemistry.
Keywords: keto-DHEA acetate, Steroids Oxidation, potassium permanganate, t-Butyl Hydroperoxide, hydroxylation
Current Organic Chemistry
Title: Catalytic Oxidative Processes in Steroid Chemistry: Allylic Oxidation, β-Selective Epoxidation, Alcohol Oxidation and Remote Functionalization Reactions
Volume: 10 Issue: 17
Author(s): Jorge A.R. Salvador, Samuel M. Silvestre and Vania M. Moreira
Affiliation:
Keywords: keto-DHEA acetate, Steroids Oxidation, potassium permanganate, t-Butyl Hydroperoxide, hydroxylation
Abstract: The preparation of steroids containing oxygenated functions in suitable positions of the steroid nucleus is of great importance and can be achieved by means of several oxidative processes. In this paper allylic oxidation, β-selective epoxidation, alcohol oxidation and remote functionalization reactions in steroid substrates are reviewed. Focus has been given to catalytic processes because of their major importance from the viewpoint of synthetic organic chemistry.
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Cite this article as:
Salvador A.R. Jorge, Silvestre M. Samuel and Moreira M. Vania, Catalytic Oxidative Processes in Steroid Chemistry: Allylic Oxidation, β-Selective Epoxidation, Alcohol Oxidation and Remote Functionalization Reactions, Current Organic Chemistry 2006; 10 (17) . https://dx.doi.org/10.2174/138527206778742641
DOI https://dx.doi.org/10.2174/138527206778742641 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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