Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

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Open Access Articles

Possible Enhancement of Photodynamic Therapy (PDT) Colorectal Cancer Treatment when Combined with Cannabidiol open Access plus

Volume: 21   Issue: 2
Pp: 137-148
Nkune W. Nkune, Cherie A. Kruger* and Heidi Abrahamse

The Killing of Human Neuroblastoma Cells by the Small Molecule JQ1 Occurs in a p53-Dependent Manner open Access plus

Volume: 20   Issue: 13
Pp: 1613-1625
Joseph Mazar*, Caleb Gordon, Varun Naga and Tamarah J. Westmoreland

Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells open Access plus

Volume: 20   Issue: 6
Pp: 687-699
Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang

Furanocoumarin A: A Novel Anticancer Agent on Human Lung Cancer A549 Cells from Fructus liquidambaris open Access plus

Volume: 19   Issue: 17
Pp: 2091-2096
Hui Fang and Hongmei Ji*

Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis open Access plus

Volume: 19   Issue: 10
Pp: 1253-1261
Naipeng Cui, Dan-Dan Lin, Yang Shen, Jian-Guo Shi, Bing Wang, Ming-Zhi Zhao, Lishuang Zheng, Hua Chen* and Jian-Hong Shi*

Nicotinamide Overcomes Doxorubicin Resistance of Breast Cancer Cells through Deregulating SIRT1/Akt Pathway open Access plus

Volume: 19   Issue: 5
Pp: 687-696
Yingze Wei, Yan Guo, Jianyun Zhou, Kui Dai, Qiang Xu and Xiaoxia Jin*

New Strategies for Therapeutic Cancer Vaccines open Access plus

Volume: 19   Issue: 2
Pp: 213-221
Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang

Trichinella spiralis and Tumors: Cause, Coincidence or Treatment? open Access plus

Volume: 18   Issue: 8
Pp: 1091-1099
Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau

Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation open Access plus

Volume: 18   Issue: 7
Pp: 1001-1008
Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*

Regulation of Apoptosis by SYB in HepG2 Liver Cancer Cells is Mediated by the P53/Caspase 9 Axis open Access plus

Volume: 17   Issue: 7
Pp: 941-947
Sharula and Zhongjun Wu*

Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals open Access plus

Volume: 16   Issue: 11
Pp: 1385-1402
Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante

Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases open Access plus

Volume: 16   Issue: 7
Pp: 810-815
Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi

The Use of Anthracyclines for Therapy of CNS Tumors open Access plus

Volume: 15   Issue: 6
Pp: 721-727
Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi

Using Cytochalasins to Improve Current Chemotherapeutic Approaches open Access plus

Volume: 15   Issue: 3
Pp: 327-335
Matthew Trendowski

Synthesis, Preferentially Hypoxic Apoptosis and Anti-Angiogenic Activity of 3- Amino-1,2,4-Benzotriazine-1,4-Dioxide Bearing Alkyl Linkers with a 3-Amino-1,2,4- Benzotriazine-1-Oxide Moiety open Access plus

Volume: 14   Issue: 10
Pp: 1428-1446
Chun-I Lee, Chien-Ming Huang, Wen-Hsin Huang and An-Rong Lee

Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment open Access plus

Volume: 14   Issue: 8
Pp: 1121-1127
Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski

Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines open Access plus

Volume: 14   Issue: 6
Pp: 840-851
Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna

β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy open Access plus

Volume: 14   Issue: 3
Pp: 343-352
Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung

The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention open Access plus

Volume: 14   Issue: 2
Pp: 233-240
Georgia Schäfer and Catherine H. Kaschula

Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells open Access plus

Volume: 14   Issue: 1
Pp: 170-180
Sunil Sagar, Luke Esau, Basem Moosa, Niveen M. Khashab, Vladimir B. Bajic and Mandeep Kaur

Differential Effects of Polyphenols on Proliferation and Apoptosis in Human Myeloid and Lymphoid Leukemia Cell Lines open Access plus

Volume: 13   Issue: 10
Pp: 1601-1613
Amani A Mahbub, Christine L. Le Maitre, Sarah L. Haywood-Small, Gordon J. McDougall, Neil A. Cross and Nicola Jordan-Mahy

The Use of Lentinan for Treating Gastric Cancer open Access plus

Volume: 13   Issue: 5
Pp: 681-688
Kenji Ina, Takae Kataoka and Takafumi Ando

Redox-inactive Analogue of Tocotrienol as a Potential Anti-cancer Agent open Access plus

Volume: 13   Issue: 3
Pp: 496-501
Tomohiro Yano, Ayami Sato, Miki Sekine, Nantiga Virgona and Masako Ota

Are KRAS/BRAF Mutations Potent Prognostic and/or Predictive Biomarkers in Colorectal Cancers? open Access plus

Volume: 12   Issue: 2
Pp: 163-171
Tomoya Yokota

Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation open Access plus

Volume: 10   Issue: 10
Pp: 753-768
Carlos Mas-Moruno, Florian Rechenmacher and Horst Kessler

Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure open Access plus

Volume: 10   Issue: 8
Pp: 617-624
Yu Toyoda and Toshihisa Ishikawa

New Medical Strategies for Midgut Carcinoids open Access plus

Volume: 10   Issue: 3
Pp: 250-269
Ola Nilsson, Yvonne Arvidsson, Viktor Johanson, Eva Forssell-Aronsson and Hakan Ahlman

Targeting RSK: An Overview of Small Molecule Inhibitors open Access plus

Volume: 8   Issue: 7
Pp: 710-716
Tam Luong Nguyen

Regulation of the Endoplasmic Reticulum Ca2+-Store in Cancer open Access plus

Volume: 8   Issue: 7
Pp: 705-709
A. Bergner and R. M. Huber

The Protein Kinase Inhibitor Balanol: Structure – Activity Relationships and Structure-Based Computational Studies open Access plus

Volume: 8   Issue: 6
Pp: 638-645
Vineet Pande, Maria J. Ramos and Federico Gago

Role of Mismatch Repair and MGMT in Response to Anticancer Therapies open Access plus

Volume: 8   Issue: 4
Pp: 368-380
Ida Casorelli, Maria Teresa Russo and Margherita Bignami

Inhibition of Protein Kinase c-Src as a Therapeutic Approach for Cancer and Bone Metastases open Access plus

Volume: 8   Issue: 3
Pp: 342-349
Nadia Rucci, Maria Susa and Anna Teti