Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Editor-in-Chief

Simone Carradori
Department of Pharmacy
“G. d’Annunzio” University of Chieti-Pescara
Chieti
(Italy)

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Most Accessed Articles

Synthetic Spirocyclohexadienones as New Anti-Migratory Compounds in Triple- Negative Breast Cancer Cell Migration

Volume: 21   Issue: 14
Pp: 1901-1910
Wanessa F. Altei, Bianca C. Pachane, Lucimara J. Martins, Ralph C. Gomes, Ricardo N. Santos, Daniara C. Fernandes, Heloisa S. Selistre-de-Araújo, Fernando Coelho * and Adriano D. Andricopulo*
DOI: 10.2174/1871520621666201207092836

Anti-MDR Effects of Quercetin and its Nanoemulsion in Multidrug-Resistant Human Leukemia Cells

Volume: 21   Issue: 14
Pp: 1911-1920
Maiara B. Marques, Ayane P. Machado, Priscila A. Santos, Michele Carrett-Dias, Gabriela S. Araújo, Barbara da Silva Alves, Bárbara Santos de Oliveira, Flavio M.R. da Silva Júnior, Cristiana L. Dora, Andrés D. Cañedo, Daza M.V.B. Filgueira, Estela Fernandes e Silva* and Ana Paula de Souza Votto
DOI: 10.2174/1871520621999210104200722

Lumiflavin Enhances the Effects of Ionising Radiation on Ovarian Cancer Stem-Like Cells by Inhibiting Autophagy

Volume: 21   Issue: 15
Pp: 2004-2011
Meiyuan Wu, Yangsheng Huang*, Zhaoxia Song and Ruhui Yang*
DOI: 10.2174/1871520621999210104201907

Anlotinib Overcomes Multiple Drug Resistant Colorectal Cancer Cells via Inactivating PI3K/AKT Pathway

Volume: 21   Issue: 15
Pp: 1987-1995
Weilan Lan, Jinyan Zhao, Wujin Chen, Haixia Shang, Jun Peng and Jiumao Lin*
DOI: 10.2174/1871520621666210112113852

Design, Synthesis and Biological Evaluation of a Novel Series of Thiadiazole- Based Anticancer Agents as Potent Angiogenesis Inhibitors

Volume: 21   Issue: 15
Pp: 2041-2049
Burcugül Altuğ-Tasa, Betül Kaya-Çavuşoğlu*, Ayşe T. Koparal, Gülhan Turan, Ali S. Koparal and Zafer A. Kaplancıklı
DOI: 10.2174/1871520621666201231143535

Anti-Tumor Activity and Underlying Mechanism of Phomoxanthone B in MCF7 Cells

Volume: 21   Issue: 14
Pp: 1825-1834
Chuan Chen, Ziyue Zhao, Qian Dong, XueHui Gao, Huibin Xu, Runlei Yang, JianChun Qin* and Duqiang Luo*
DOI: 10.2174/1871520620999201124215511

1,3,4-Thiadiazolo (3,2-Α) Pyrimidine-6-Carbonitrile Scaffold as PARP1 Inhibitors

Volume: 21   Issue: 15
Pp: 2050-2065
Lakshmanan Kaviarasan, Elizabeth Eldhose, Praveen T. Krishnamurthy, Kalirajan Rajagopal, Manal Mohammed, Pulla Prudviraj and Gowramma Byran*
DOI: 10.2174/1871520621666201216095018

Recent Advances on Epidermal Growth Factor Receptor as a Molecular Target for Breast Cancer Therapeutics

Volume: 21   Issue: 14
Pp: 1783-1792
Swathi R. Shetty, Ragini Yeeravalli, Tanya Bera and Amitava Das*
DOI: 10.2174/1871520621666201222143213

Alpha-Terpineol as Antitumor Candidate in Pre-Clinical Studies

Volume: 21   Issue: 15
Pp: 2023-2031
Helber A. Negreiros, Kariely Gonçalves de Moura, Maria L.L. Barreto do Nascimento, Débora Caroline do Nascimento Rodrigues, Paulo M.P. Ferreir, Débora C. Braz, Marlene Gomes de Farias, Layde de Sousa Corrêia, Ana R.S. Pereira, Lubna K.B. Santos, Juan C.R. Gonçalves, Anderson N. Mendes, Felipe C. Carneiro da Silva, Ana A.C.M. Cavalcant and Joáo Marcelo de Castro e Sousa*
DOI: 10.2174/1871520621999210104195820

The Efficacy and Safety of Additional Anti-HER2-Targeting Drugs in the Treatment of HER2-Positive Advanced Breast Cancer: A Meta-Analysis

Volume: 21   Issue: 14
Pp: 1931-1940
Nannan Du, Bangsheng Chen, Zefeng Shen, Bin Zhou, Xiaojun Fu, Danyi Mao, Feiyan Mao, Derry M. Ng, Parikshit A. Khadaroo and Lei Yang*
DOI: 10.2174/1871520621666201231142841

Recombinant Human IL-11 Promotes Lung Adenocarcinoma A549 Cell Growth and EMT through Activating STAT3/HIF-1α/EMT Signaling Pathway

Volume: 21   Issue: 15
Pp: 1996-2003
Na Peng, Meijun Lu, Mafei Kang*, Xiuli Liu, Bihui Li and Cuimei Dong
DOI: 10.2174/1871520621666201207091248

Application of Diffusion Weighted Imaging in Prostate Cancer Bone Metastasis: Detection and Therapy Evaluation

Volume: 21   Issue: 15
Pp: 1950-1956
Xue-Qin Gong, Yun-Yun Tao, Ran Wang, Nian Liu, Xiao-Hua Huang, Jing Zheng, Cui Yang, Lin Yang* and Xiao-Ming Zhang
DOI: 10.2174/1871520621666210118092641

Novel Anticancer Dimeric Naphthoquinones from Diospyros lotus having Anti- Tumor, Anti-Inflammatory and Multidrug Resistance Reversal Potential: In Vitro, In Vivo and In Silico Evidence

Volume: 21   Issue: 15
Pp: 2089-2097
Abdur Rauf*, Ajmal Khan*, Tareq Abu-Izneid, Fahad A. Alhumaydhi, Saud Bawazeer, Muslim Raza, Haroon Khan, Seema Patel and Ahmed Al-Harrasi*
DOI: 10.2174/1871520621666210112113127

The Relevance of Supplemental Vitamin D in Malignancies

Volume: 21   Issue: 15
Pp: 1942-1949
Delia Nica-Badea* and Aurelian Udristioiu
DOI: 10.2174/1871520621666210112115846

Hydrophobic and Hydrophilic Film-Forming Gels for the Controlled Delivery of Drugs with Different Levels of Hydrophobicity

Volume: 21   Issue: 15
Pp: 2082-2088
Khanh T. Nguyen, Phuong H.L. Tran, Hai V. Ngo and Thao T.D. Tran*
DOI: 10.2174/1871520621666201231141842