Anti-Cancer Agents in Medicinal Chemistry

Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I

Volume:20   Issue:7
Pp: 887-896
Yeliz Demir *, Cüneyt Türkeş and Şükrü Beydemir
DOI: 10.2174/1871520620666200218110645

Evaluation of Anticancer, Antibacterial and Antioxidant Properties of a Medicinally Treasured Fern Tectaria coadunata with its Phytoconstituents Analysis by HR-LCMS

Volume:20   Issue:15
Pp: 1845-1856
Mandadi N. Reddy, Mohd. Adnan*, Mousa M. Alreshidi, Mohd. Saeed and Mitesh Patel
DOI: 10.2174/1871520620666200318101938

CDK1 in Breast Cancer: Implications for Theranostic Potential

Volume:20   Issue:7
Pp: 758-767
Sepideh Izadi, Afshin Nikkhoo, Mohammad Hojjat-Farsangi, Afshin Namdar, Gholamreza Azizi, Hamed Mohammadi, Mehdi Yousefi and Farhad Jadidi-Niaragh*
DOI: 10.2174/1871520620666200203125712

Beta-Caryophyllene Suppresses Ovarian Cancer Proliferation by Inducing Cell Cycle Arrest and Apoptosis

Volume:20   Issue:13
Pp: 1530-1537
Santhosh Arul, Harinee Rajagopalan, Jivitesh Ravi and Haripriya Dayalan*
DOI: 10.2174/1871520620666200227093216

Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer

Volume:20   Issue:1
Pp: 70-83
Mohamed A. Tantawy, Farid M. Sroor*, Magda F. Mohamed*, Mostafa E. El-Naggar, Fatma M. Saleh, Hamdi M. Hassaneen and Ismail A. Abdelhamid*
DOI: 10.2174/1871520619666191024121116

Nanoformulations of Coumarins and the Hybrid Molecules of Coumarins with Potential Anticancer Effects

Volume:20   Issue:15
Pp: 1797-1816
Mukerrem Betul Yerer*, Serkan Dayan, M. Ihsan Han, Ajay Sharma, Hardeep S. Tuli and Katrin Sak
DOI: 10.2174/1871520620666200310094646

Recent Advances of Silver Nanoparticles in Cancer Diagnosis and Treatment

Volume:20   Issue:11
Pp: 1276-1287
Tran Q. Huy*, Pham T.M. Huyen, Anh-Tuan Le and Matteo Tonezzer*
DOI: 10.2174/1871520619666190710121727

Ruxolitinib Regulates the Autophagy Machinery in Multiple Myeloma Cells

Volume:20   Issue:18
Pp: 2316-2323
Alican Kusoglu*, Bakiye G. Bagca, Neslihan P.O. Ay, Guray Saydam and Cigir B. Avci
DOI: 10.2174/1871520620666200218105159

Apoptotic Effects of Melittin on 4T1 Breast Cancer Cell Line is associated with Up Regulation of Mfn1 and Drp1 mRNA Expression

Volume:20   Issue:7
Pp: 790-799
Farnaz D. Moghaddam, Pejman Mortazavi*, Somayeh Hamedi, Mohammad Nabiuni and Nasim H. Roodbari
DOI: 10.2174/1871520620666200211091451

Dietary Phenolic Acids and Flavonoids as Potential Anti-Cancer Agents: Current State of the Art and Future Perspectives

Volume:20   Issue:1
Pp: 29-48
Ramesh K. Bonta*
DOI: 10.2174/1871520619666191019112712

Anti-Metastatic Effects of Lupeol via the Inhibition of MAPK/ERK Pathway in Lung Cancer

Volume:21   Issue:2
Pp: 201-206
Mital Bhatt, Mitesh Patel*, Mohd Adnan and Mandadi N. Reddy
DOI: 10.2174/1871520620666200424131548

Aromatase Inhibitors for the Treatment of Breast Cancer: A Journey from the Scratch

Volume:20   Issue:17
Pp: 1994-2004
Pooja Ratre, Keerti Mishra, Amit Dubey, Amber Vyas, Akhlesh Jain* and Suresh Thareja*
DOI: 10.2174/1871520620666200627204105

The Anticancer Properties of Silibinin: Its Molecular Mechanism and Therapeutic Effect in Breast Cancer

Volume:20   Issue:15
Pp: 1787-1796
Agata Binienda, Sylwia Ziolkowska and Elzbieta Pluciennik*
DOI: 10.2174/1871520620666191220142741

Resveratrol and other Stilbenes: Effects on Dysregulated Gene Expression in Cancers and Novel Delivery Systems

Volume:21   Issue:5
Pp: 567-574
Palmiro Poltronieri*, Baojun Xu and Giovanna Giovinazzo
DOI: 10.2174/1871520620666200705220722

Molecular Docking, Antioxidant, Anticancer and Antileishmanial Effects of Newly Synthesized Quinoline Derivatives

Volume:20   Issue:13
Pp: 1516-1529
Zoonish Malghani, Arif-Ullah Khan*, Muhammad Faheem, Muhammad Z. Danish, Humaira Nadeem, Sameen F. Ansari and Madeeha Maqbool
DOI: 10.2174/1871520620666200516145117

The Synthesis, Anticancer Activity, Structure-Activity Relationships and Molecular Modelling Studies of Novel Isoindole-1,3(2H)-dione Compounds Containing Different Functional Groups

Volume:20   Issue:11
Pp: 1368-1378
Ayse Tan*, Serap Kizilkaya, Unzile Kelestemur, Atilla Akdemir and Yunus Kara
DOI: 10.2174/1871520620666200410080648

Quercetin-Mediated Apoptosis and Cellular Senescence in Human Colon Cancer

Volume:20   Issue:11
Pp: 1387-1396
Serpil Özsoy*, Eda Becer, Hilal Kabadayı, Hafize S. Vatansever and Sevinç Yücecan
DOI: 10.2174/1871520620666200408082026

The Citrus Flavanone Hesperetin Induces Apoptosis in CTCL Cells via STAT3/Notch1/NFκB-Mediated Signaling Axis

Volume:20   Issue:12
Pp: 1459-1468
Amuthavalli Kottaiswamy*, Atish Kizhakeyil, Abirami M. Padmanaban , Fathima B. Mirza, Venkatesh R. Vijay, Pin S. Lee, Navin K. Verma, Parkavi Kalaiselvan and Shila Samuel *
DOI: 10.2174/1871521409666200324110031

Resveratrol Counteracts Hypoxia-Induced Gastric Cancer Invasion and EMT through Hedgehog Pathway Suppression

Volume:20   Issue:9
Pp: 1105-1114
Qin-Hong Xu, Ying Xiao, Xu-Qi Li*, Lin Fan*, Can-Can Zhou, Liang Cheng, Zheng-Dong Jiang and Guang-Hui Wang
DOI: 10.2174/1871520620666200402080034

Molecular Identification of Phytochemical for Anticancer Treatment

Volume:20   Issue:6
Pp: 651-666
Kanchana Usuwanthim*, Prapakorn Wisitpongpun and Thitiya Luetragoon
DOI: 10.2174/1871520620666200213110016

Evaluation of the Diagnostic Properties of Serum hsa-miR-223-5p in the Detection of Gastric Cancer: A Case-Control Study

Volume:20   Issue:7
Pp: 800-808
Amir H. Aalami, Vahid Pouresmaeil*, Amir Amirabadi, Fatemeh H. Mojahed, Mahdi Q. Rad and Amirhossein Sahebkar*
DOI: 10.2174/1871520620666200204100602

Anti-Tumour Activity of Glycodendrimer Nanoparticles in a Subcutaneous MEC-1 Xenograft Model of Human Chronic Lymphocytic Leukemia

Volume:20   Issue:3
Pp: 325-334
Barbara Ziemba, Hanna Sikorska, Magdalena Jander, Wojciech Kuncman, Marian Danilewicz, Dietmar Appelhans, Maria Bryszewska, Maciej Borowiec and Ida Franiak-Pietryga*
DOI: 10.2174/1871520619666191019093558

Targeted Nanoparticles for Co-delivery of 5-FU and Nitroxoline, a Cathepsin B Inhibitor, in HepG2 Cells of Hepatocellular Carcinoma

Volume:20   Issue:3
Pp: 346-358
Jaleh Varshosaz*, Monireh M. Fard, Mina Mirian and Farshid Hassanzadeh
DOI: 10.2174/1871520619666190930124746

The Effect of a Newly Synthesized Ferrocene Derivative against MCF-7 Breast Cancer Cells and Spheroid Stem Cells through ROS Production and Inhibition of JAK2/STAT3 Signaling Pathway

Volume:20   Issue:7
Pp: 875-886
Mitra Nourbakhsh, Shabnam Farzaneh, Adeleh Taghikhani, Afshin Zarghi* and Shokoofe Noori*
DOI: 10.2174/1871520620666200101151743

New Uracil Analogs with Exocyclic Methylidene Group as Potential Anticancer Agents

Volume:20   Issue:3
Pp: 359-368
Angelika Długosz-Pokorska, Joanna Drogosz, Marlena Pięta, Tomasz Janecki, Urszula Krajewska, Marek Mirowski and Anna Janecka*
DOI: 10.2174/1871520619666191211104128