Anti-Cancer Agents in Medicinal Chemistry

Synthetic Spirocyclohexadienones as New Anti-Migratory Compounds in Triple- Negative Breast Cancer Cell Migration

Volume: 21   Issue: 14
Pp: 1901-1910
Wanessa F. Altei, Bianca C. Pachane, Lucimara J. Martins, Ralph C. Gomes, Ricardo N. Santos, Daniara C. Fernandes, Heloisa S. Selistre-de-Araújo, Fernando Coelho * and Adriano D. Andricopulo*
DOI: 10.2174/1871520621666201207092836

Anti-MDR Effects of Quercetin and its Nanoemulsion in Multidrug-Resistant Human Leukemia Cells

Volume: 21   Issue: 14
Pp: 1911-1920
Maiara B. Marques, Ayane P. Machado, Priscila A. Santos, Michele Carrett-Dias, Gabriela S. Araújo, Barbara da Silva Alves, Bárbara Santos de Oliveira, Flavio M.R. da Silva Júnior, Cristiana L. Dora, Andrés D. Cañedo, Daza M.V.B. Filgueira, Estela Fernandes e Silva* and Ana Paula de Souza Votto
DOI: 10.2174/1871520621999210104200722

Effects of Mucoadhesive Polymers on Released Particles and Drug Release in Solid Lipid Particle-Based Buccal Tablets

Volume: 21   Issue: 14
Pp: 1894-1900
Thuy T.H. Phan, Phuong H.L. Tran and Thao T.D. Tran*
DOI: 10.2174/1871520621666201207091827

Anti-Tumor Activity and Underlying Mechanism of Phomoxanthone B in MCF7 Cells

Volume: 21   Issue: 14
Pp: 1825-1834
Chuan Chen, Ziyue Zhao, Qian Dong, XueHui Gao, Huibin Xu, Runlei Yang, JianChun Qin* and Duqiang Luo*
DOI: 10.2174/1871520620999201124215511

The Efficacy and Safety of Additional Anti-HER2-Targeting Drugs in the Treatment of HER2-Positive Advanced Breast Cancer: A Meta-Analysis

Volume: 21   Issue: 14
Pp: 1931-1940
Nannan Du, Bangsheng Chen, Zefeng Shen, Bin Zhou, Xiaojun Fu, Danyi Mao, Feiyan Mao, Derry M. Ng, Parikshit A. Khadaroo and Lei Yang*
DOI: 10.2174/1871520621666201231142841

Recent Advances on Epidermal Growth Factor Receptor as a Molecular Target for Breast Cancer Therapeutics

Volume: 21   Issue: 14
Pp: 1783-1792
Swathi R. Shetty, Ragini Yeeravalli, Tanya Bera and Amitava Das*
DOI: 10.2174/1871520621666201222143213

FOXM1-Dependent Transcriptional Regulation of EZH2 Induces Proliferation and Progression in Prostate Cancer

Volume: 21   Issue: 14
Pp: 1835-1841
Juan-Hua Tian, Li-Jun Mu, Mei-Yu Wang, Jin Zeng, Qing-Zhi Long, Bin-Guan, Wen Wang, Yu-Mei Jiang, Xiao-Jing Bai and Yue-Feng Du*
DOI: 10.2174/1871520620666200731161810

99mTechnetium- or Cy7-Labeled Fab(Tocilizumab) as Potential Multiple Myeloma Imaging Agents

Volume: 21   Issue: 14
Pp: 1883-1893
Ximena Camacho*, Carolina Perroni, Camila L. Machado, Camila de Godoi Carneiro, Mara de Souza Junqueira, Daniele Faria, María F. García, Marcelo Fernández, Natalia Oddone, Juan Benech, Carlos A. Buchpiguel, Hugo Cerecetto, Roger Chammas, Eloisa Riva, Pablo Cabral and Juan P. Gambini
DOI: 10.2174/1871520621999210104181238

Anticancer Potential of Doxorubicin in Combination with Green-Synthesized Silver Nanoparticle and its Cytotoxicity Effects on Cardio-Myoblast Normal Cells

Volume: 21   Issue: 14
Pp: 1842-1849
Jafar Saeidi, Samaneh Dolatabadi, Mahbubeh B. Esfahani, Masood Saeidi, Mahnaz Mohtashami*, Kiana Mokhtari and Ahmad Ghasemi*
DOI: 10.2174/1871520621666201207093913

Recent Development in Indole Derivatives as Anticancer Agent: A Mechanistic Approach

Volume: 21   Issue: 14
Pp: 1802-1824
Neha Devi, Kamalpreet Kaur, Avadh Biharee and Vikas Jaitak*
DOI: 10.2174/1871520621999210104192644

Evaluation of Anti-Tumor Potential of Lactobacillus acidophilus ATCC4356 Culture Supernatants in MCF-7 Breast Cancer

Volume: 21   Issue: 14
Pp: 1861-1870
Ramazan Behzadi, Ahmad Hormati, Karim Eivaziatashbeik, Sajjad Ahmadpour*, Fatemeh Khodadust, Fatemeh Zaboli, Esmail Fattahi, Rana Jahanban-­Esfahlan and Khaled Seidi
DOI: 10.2174/1871520621666201207085239

Plant Mediated Silver Nanoparticles and Mode of Action in Cancer Therapy: A Review

Volume: 21   Issue: 14
Pp: 1793-1801
Rama Sharma* and Nancy Srivastava
DOI: 10.2174/1871520621666201207085900

Novel Scopoletin Derivatives Kill Cancer Cells by Inducing Mitochondrial Depolarization and Apoptosis

Volume: 21   Issue: 14
Pp: 1774-1782
Zhixian Shi, Li Chen* and Jianbo Sun*
DOI: 10.2174/1871520621666201207094416

Apoptotic Effects of Bilirubin on Skin Cancer Cell Lines SK-MEL-3 (Melanoma) and A431 (Non-Melanoma)

Volume: 21   Issue: 14
Pp: 1871-1882
Javad Saffari-Chaleshtori, Esfandiar Heidarian and Sayed M. Shafiee*
DOI: 10.2174/1871520621999201208201134

Panax notoginseng Saponins Promote Cell Death and Chemosensitivity in Pancreatic Cancer through the Apoptosis and Autophagy Pathways

Volume: 21   Issue: 13
Pp: 1680-1688
Li-Chao Yao, Lun Wu, Wei Wang, Lu-Lu Zhai, Lin Ye, Feng Xiang and Zhi-Gang Tang*
DOI: 10.2174/1871520620999201110191459

Combination of Histone Deacetylase Inhibitor with Cu(II) 5,5-diethylbarbiturate Complex Induces Apoptosis in Breast Cancer Stem Cells: A Promising Novel Approach

Volume: 21   Issue: 14
Pp: 1850-1860
Merve Erkisa, Nazlihan Aztopal, Elif Erturk, Engin Ulukaya, Veysel T. Yilmaz and Ferda Ari*
DOI: 10.2174/1871520621666201207090702

Chalcone Scaffolds as Anticancer Drugs: A Review on Molecular Insight in Action of Mechanisms and Anticancer Properties

Volume: 21   Issue: 13
Pp: 1650-1670
Shefali Shukla, Anantpreet K. Sood, Kartika Goyal, Ambika Singh, Vaidehi Sharma, Neha Guliya, Shikha Gulati and Sanjay Kumar*
DOI: 10.2174/1871520620999201124212840

The Potential Clinical Value of Curcumin and its Derivatives in Colorectal Cancer

Volume: 21   Issue: 13
Pp: 1626-1637
Zhaoying Yao, Thi Ha Le, Qianming Du, Huiwen Mu, Chao Liu* and Yubing Zhu*
DOI: 10.2174/1871520620999201113095821

Effect of Dasatinib on Genes Related to Mitotic Catastrophe Pathway in Chronic Myeloid Leukemia Cells

Volume: 21   Issue: 13
Pp: 1724-1731
Sezgi Kipcak, Buket Ozel, Cigir B. Avci*, Leila S. Takanlou, Maryam S. Takanlou, Cumhur Gunduz and Nur S. Gunel
DOI: 10.2174/1871520620666201106085929

Synthesis, Molecular Docking and Biological Activity Evaluation of Alkoxy Substituted Chalcone Derivatives: Potential Apoptosis Inducing Agent on MCF-7 Cells

Volume: 21   Issue: 13
Pp: 1738-1750
Wan M. Khairul*, Fatimah Hashim*, Mas Mohammed, Nurul S.M.N. Shah, Syed A.T.T. Johari, Rafizah Rahamathullah, Adibah I. Daud and Nyuk L. Ma
DOI: 10.2174/1871520620999201110190709