Anti-Cancer Agents in Medicinal Chemistry

Palladium (II) Complex Enhances ROS-Dependent Apoptotic Effects via Autophagy Inhibition and Disruption of Multiple Signaling Pathways in Colorectal Cancer Cells

Volume: 21   Issue: 10
Pp: 1284-1291
Seyma Aydinlik, Merve Erkisa, Ferda Ari, Serap Celikler and Engin Ulukaya*
DOI: 10.2174/1871520620666200929153804

miRNAs Modulate the Dichotomy of Cisplatin Resistance or Sensitivity in Breast Cancer: An Update of Therapeutic Implications

Volume: 21   Issue: 9
Pp: 1069-1081
Asma Safi, Milad Bastami, Soheila Delghir, Khandan Ilkhani, Farhad Seif and Mohammad R. Alivand*
DOI: 10.2174/1871520620666200903145939

On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7)

Volume: 21   Issue: 9
Pp: 1172-1182
Celisnolia M. Leite*, João Honorato de Araujo-Neto, Rodrigo S. Corrêa, Legna Colina-Vegas, Diego Martínez-Otero, Paulo R. Martins, Cristiane G. Silva and Alzir A. Batista*
DOI: 10.2174/1871520620666200824114816

A New Series of Antileukemic Agents: Design, Synthesis, In Vitro and In Silico Evaluation of Thiazole-Based ABL1 Kinase Inhibitors

Volume: 21   Issue: 9
Pp: 1099-1109
Ebru Zeytün, Mehlika D. Altıntop*, Belgin Sever, Ahmet Özdemir, Doha E. Ellakwa, Zeynep Ocak, Halil I. Ciftci, Masami Otsuka, Mikako Fujita* and Mohamed O. Radwan*
DOI: 10.2174/1871520620666200824100408

The Use of Bio-Active Compounds of Citrus Fruits as Chemopreventive Agents and Inhibitor of Cancer Cells Viability

Volume: 21   Issue: 9
Pp: 1058-1068
Mahboubeh Tajaldini and Jahanbakhsh Asadi*
DOI: 10.2174/1871520620666200721105505

Possible Enhancement of Photodynamic Therapy (PDT) Colorectal Cancer Treatment when Combined with Cannabidiol open access plus

Volume: 21   Issue: 2
Pp: 137-148
Nkune W. Nkune, Cherie A. Kruger* and Heidi Abrahamse
DOI: 10.2174/1871520620666200415102321

Exploring the Molecular Mechanism of Cinnamic Acid-Mediated Cytotoxicity in Triple Negative MDA-MB-231 Breast Cancer Cells

Volume: 21   Issue: 9
Pp: 1141-1150
Ambika Pal, Poulami Tapadar and Ranjana Pal*
DOI: 10.2174/1871520620666200807222248

Characterization of Dopamine Receptor Associated Drugs on the Proliferation and Apoptosis of Prostate Cancer Cell Lines

Volume: 21   Issue: 9
Pp: 1160-1171
Fatemeh Akbarian, Farid Dadkhah, Arezoo Campbell, Farrokh Asadi and Ghasem Ahangari*
DOI: 10.2174/1871520620999200831110243

The Natural Flavonoid Naringenin Inhibits the Cell Growth of Wilms Tumor in Children by Suppressing TLR4/NF-κB Signaling

Volume: 21   Issue: 9
Pp: 1120-1126
Hongtao Li*, Peng Chen, Lei Chen and Xinning Wang
DOI: 10.2174/1871520620999200818155814

The Engaged Role of Tumor Microenvironment in Cancer Metabolism: Focusing on Cancer-Associated Fibroblast and Exosome Mediators

Volume: 21   Issue: 2
Pp: 254-266
Khandan Ilkhani, Milad Bastami, Soheila Delgir, Asma Safi, Shahrzad Talebian and Mohammad-Reza Alivand*
DOI: 10.2174/1871520620666200910123428

Synergistic Combination of Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid and Natural Flavonoid Curcumin Exhibits Anticancer and Antibacterial Activity

Volume: 21   Issue: 10
Pp: 1301-1308
Ergül M. Altundağ *, Kübra Toprak, Gizem Şanlıtürk, Mümtaz Güran, Cahit Özbilenler, Namık R. Kerküklü, Ayşe M. Yılmaz and Ahmet S. Yalçın
DOI: 10.2174/1871520620666201006141317

Transcriptionomic Study on Apoptosis of SKOV-3 Cells Induced by Phycoerythrin from Gracilaria lemaneiformis

Volume: 21   Issue: 10
Pp: 1240-1249
Jun Ying, Zhouhao Tang, Guanan Zhao, Xia Li, Ruowang Pan, Shuangxiang Lin, Yang Lou, Wanping Wang, Peizhen Li*, Qiyu Bao* and Chunxia Yan*
DOI: 10.2174/1871520620666200908102621

Protective Effect of Resveratrol against Glioblastoma: A Review

Volume: 21   Issue: 10
Pp: 1216-1227
Milad Ashrafizadeh, Reza Mohammadinejad, Tahereh Farkhondeh and Saeed Samarghandian*
DOI: 10.2174/1871520620666200929151139

Synthesis and in vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents

Volume: 21   Issue: 9
Pp: 1127-1140
Upasana Yadav, Yogesh Vanjari, Kritika Laxmikeshav, Ramya Tokala, Praveen K. Niggula, Manoj Kumar, Venu Talla*, Ahmed Kamal and Nagula Shankaraiah*
DOI: 10.2174/1871520620666200714142931

Preparation, Characterization and In Vitro Biological Evaluation of Novel Curcumin Derivatives as Cytotoxic and Apoptosis-Inducing Agents

Volume: 21   Issue: 10
Pp: 1309-1322
Omid K. Arjomandi, Saiedeh Almasi, Leila Hosseinzadeh, Mahboubeh Kavoosi and Hadi Adibi*
DOI: 10.2174/1871520620666201002111205

Synthesis and Cytotoxic Properties of New Substituted Glycosides-Indole Conjugates as Apoptosis Inducers in Cancer Cells

Volume: 21   Issue: 10
Pp: 1323-1333
Aladdin M. Srour, Mohamed N. El-Bayaa*, Mervat M. Omran, Marwa M. Sharaky and Wael A. El-Sayed*
DOI: 10.2174/1871520620666200929155246

Activation of Myosin Phosphatase by Epigallocatechin-Gallate Sensitizes THP-1 Leukemic Cells to Daunorubicin

Volume: 21   Issue: 9
Pp: 1092-1098
Emese Tóth, Ferenc Erdődi and Andrea Kiss*
DOI: 10.2174/1871520620666200717142315

Targeted Protein Degradation: An Emerging Therapeutic Strategy in Cancer

Volume: 21   Issue: 2
Pp: 214-230
Samir H. Barghout*
DOI: 10.2174/1871520620666200410082652

New Hybrid Scaffolds Based on Carbazole-Chalcones as Potent Anticancer Agents

Volume: 21   Issue: 9
Pp: 1082-1091
Faisal Rashid, Sumera Zaib, Aliya Ibrar*, Syeda A. Ejaz, Aamer Saeed, Imtiaz Khan* and Jamshed Iqbal*
DOI: 10.2174/1871520620666200721110732

Chloroform Fraction of Methanolic Extract of Seeds of Annona muricata Induce S Phase Arrest and ROS Dependent Caspase Activated Mitochondria-Mediated Apoptosis in Triple-Negative Breast Cancer

Volume: 21   Issue: 10
Pp: 1250-1265
Bibu J. Kariyil*, Usha P.T. Ayyappan, Anu Gopalakrishnan and Ajith J. George
DOI: 10.2174/1871520620666200918101448