Anti-Cancer Agents in Medicinal Chemistry

Lauric Acid Modulates Cancer-Associated microRNA Expression and Inhibits the Growth of the Cancer Cell

Volume: 20   Issue: 7
Pp: 834-844
Poonam Verma, Amit Ghosh*, Manisha Ray and Saurav Sarkar
DOI: 10.2174/1871520620666200310091719

Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells open access plus

Volume: 20   Issue: 6
Pp: 687-699
Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang
DOI: 10.2174/1871520620666200213102849

The Effect of a Newly Synthesized Ferrocene Derivative against MCF-7 Breast Cancer Cells and Spheroid Stem Cells through ROS Production and Inhibition of JAK2/STAT3 Signaling Pathway

Volume: 20   Issue: 7
Pp: 875-886
Mitra Nourbakhsh, Shabnam Farzaneh, Adeleh Taghikhani, Afshin Zarghi* and Shokoofe Noori*
DOI: 10.2174/1871520620666200101151743

Lemon Juice as a Biocatalyst Under Ultrasound Irradiation: Synthesis and Pharmacological Evaluation of 2-amino 1,3,4-thiadiazoles

Volume: 20   Issue: 11
Pp: 1379-1386
Malavattu G. Prasad, Chapala V. Lakshmi, Naresh K. Katari* and Manojit Pal*
DOI: 10.2174/1871520620666200409143513

Modulating Pluripotency Network Genes with Omega-3 DHA is followed by Caspase- 3 Activation and Apoptosis in DNA Mismatch Repair-Deficient/KRAS-Mutant Colorectal Cancer Stem-Like Cells

Volume: 20   Issue: 10
Pp: 1221-1232
Nazila Mahmoudi, Nowruz Delirezh and Mohammad Reza Sam*
DOI: 10.2174/1871520620666200302113722

The Engaged Role of Tumor Microenvironment in Cancer Metabolism: Focusing on Cancer-Associated Fibroblast and Exosome Mediators

Volume: 21   Issue: 2
Pp: 254-266
Khandan Ilkhani, Milad Bastami, Soheila Delgir, Asma Safi, Shahrzad Talebian and Mohammad-Reza Alivand*
DOI: 10.2174/1871520620666200910123428

The Anti-Tumor Activity of Afatinib in Pancreatic Ductal Adenocarcinoma Cells

Volume: 20   Issue: 12
Pp: 1447-1458
Zhenyu Ye, Yecheng Li, Jiaming Xie, Zhenyu Feng, Xiaodong Yang, Yong Wu, Kui Zhao, Yuwei Pu, Xiangrong Xu, Zhaobi Zhu, Wei Li, Jun Pan, Wei Chen* and Chungen Xing*
DOI: 10.2174/1871520620666200508090515

Possible Enhancement of Photodynamic Therapy (PDT) Colorectal Cancer Treatment when Combined with Cannabidiol open access plus

Volume: 21   Issue: 2
Pp: 137-148
Nkune W. Nkune, Cherie A. Kruger* and Heidi Abrahamse
DOI: 10.2174/1871520620666200415102321

Flavonoid-Based Cancer Therapy: An Updated Review

Volume: 20   Issue: 12
Pp: 1398-1414
Elham Hosseinzadeh, Ali Hassanzadeh, Faroogh Marofi, Mohammad Reza Alivand and Saeed Solali*
DOI: 10.2174/1871520620666200423071759

Targeted Protein Degradation: An Emerging Therapeutic Strategy in Cancer

Volume: 21   Issue: 2
Pp: 214-230
Samir H. Barghout*
DOI: 10.2174/1871520620666200410082652

A Review of Chemotherapy and Photodynamic Therapy for Lung Cancer Treatment

Volume: 21   Issue: 2
Pp: 149-161
Ahmed El-Hussein*, Sello L. Manoto, Saturnin Ombinda-Lemboumba, Ziya A. Alrowaili and Patience Mthunzi-Kufa
DOI: 10.2174/1871520620666200403144945

Concise Synthesis of 1,1-Diarylvinyl Sulfones and Investigations on their Antiproliferative Activity via Tubulin Inhibition

Volume: 20   Issue: 12
Pp: 1469-1474
Lavanya Reddy, Suja T. Dharmabalan*, Kanakaraju Manupati, Ragini Yeeravalli, Lakshmi D. Vijay, Kavitha Donthiboina, Vadithe Lakshma Naik and Amitava Das
DOI: 10.2174/1871520620666200423075630

Resveratrol Counteracts Hypoxia-Induced Gastric Cancer Invasion and EMT through Hedgehog Pathway Suppression

Volume: 20   Issue: 9
Pp: 1105-1114
Qin-Hong Xu, Ying Xiao, Xu-Qi Li*, Lin Fan*, Can-Can Zhou, Liang Cheng, Zheng-Dong Jiang and Guang-Hui Wang
DOI: 10.2174/1871520620666200402080034

Exogenous Expression of WNT7A in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents

Volume: 20   Issue: 12
Pp: 1504-1514
Monserrat Alvarez-Zavala, Christian Barreto-Vargas, Luis A. Torres-Reyes, Roberto F. De la Peña-Castro, Adriana Aguilar-Lemarroy and Luis F. Jave-Suarez*
DOI: 10.2174/1871520620666200521114100

N-Terminal-Dependent Protein Degradation and Targeting Cancer Cells

Volume: 21   Issue: 2
Pp: 231-236
Mohamed A. Eldeeb*
DOI: 10.2174/1871520620666200819112632

UBE2L6 is Involved in Cisplatin Resistance by Regulating the Transcription of ABCB6

Volume: 20   Issue: 12
Pp: 1487-1496
Midori Murakami, Hiroto Izumi*, Tomoko Kurita, Chiho Koi, Yasuo Morimoto and Kiyoshi Yoshino
DOI: 10.2174/1871520620666200424130934

Phanginin R Induces Cytoprotective Autophagy via JNK/c-Jun Signaling Pathway in Non-Small Cell Lung Cancer A549 Cells

Volume: 20   Issue: 8
Pp: 982-988
Le-Le Zhang, Han Bao, Yu-Lian Xu, Xiao-Ming Jiang, Wei Li, Liang Zou, Li-Gen Lin* and Jin-Jian Lu*
DOI: 10.2174/1871520620666200414095828

Selective Photodynamic Effects on Breast Cancer Cells Provided by p123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery

Volume: 20   Issue: 11
Pp: 1352-1367
Gabrielle Marconi Zago Ferreira Damke, Raquel Pantarotto Souza, Maiara Camotti Montanha, Edilson Damke, Renato Sonchini Gonçalves, Gabriel Batista César, Elza Kimura, Wilker Caetano, Noboru Hioka and Marcia Edilaine Lopes Consolaro*
DOI: 10.2174/1871520618666181102091010

The Synthesis, Anticancer Activity, Structure-Activity Relationships and Molecular Modelling Studies of Novel Isoindole-1,3(2H)-dione Compounds Containing Different Functional Groups

Volume: 20   Issue: 11
Pp: 1368-1378
Ayse Tan*, Serap Kizilkaya, Unzile Kelestemur, Atilla Akdemir and Yunus Kara
DOI: 10.2174/1871520620666200410080648

Antibody-Based Targeted Interventions for the Diagnosis and Treatment of Skin Cancers

Volume: 21   Issue: 2
Pp: 162-186
Suresh Madheswaran, Neelakshi Mungra, Fleury A.N. Biteghe, Jean De la Croix Ndong, Afolake T. Arowolo, Henry A. Adeola, Dharanidharan Ramamurthy, Krupa Naran, Nonhlanhla P. Khumalo and Stefan Barth*
DOI: 10.2174/1871520620666200728123006