Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Editor-in-Chief

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
(France)

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Articles Ahead of Print

Characterization of Cepharanthin Nanosuspensions and an Evaluation of Their In Vitro Activity for the HepG2 Hepatocellular Carcinoma Cell Line

Volume:20
Yue Zhao, Tingting Fu, Gaoke Meng, Fangxia Qiao, Yanhui Hou, Yanhua Liu and Jianhong Yang*

Rotundic Acid Regulates the Effects of Let-7f-5p on Caco2 Cell Proliferation

Volume:20
Yuan Feng, Xinran Liu, Yueqing Han, Mantian Chen, Lin Zhang, Yuling Hu, Liya Chen, Gang Chen and Ning Li*

Targeting CD47 Inhibits Tumor Development and Increases Phagocytosis in Oral Squamous Cell Carcinoma

Volume:20
Xiao-Jing Ye, Jian-Guang Yang, Ya-Qin Tan, Xiao-Jie Chen and Gang Zhou*

Therapy Resistance in Cancers: Phenotypic, Metabolic, Epigenetic and Tumour Microenvironmental Perspectives

Volume:20
Tasnim Zahan, Plabon K. Das, Syeda F. Akter, Rowshanul Habib, Md. Habibur Rahman, Md. Rezaul Karim and Farhadul Islam*

Derivatives of Deoxypodophyllotoxin Induce Apoptosis Through Bcl-2/Bax Proteins Expression

Volume:20
Ya-Nan Li, Ni Ning, Lei Song, Yun Geng, Jun-Ting Fan, Chao-Ying Ma* and He-Zhong Jiang*

Antioxidant and Antiproliferative Activity of Selected Medicinal Plants of Lower Assam, India: An In Vitro and In Silico Study

Volume:20
Ananta Swargiary*, Akalesh K. Verma, Sweta Singh, Mritunjoy K. Roy and Manita Daimari

Periplogenin Activates ROS-ER Stress Pathway to Trigger Apoptosis via BIP-eIF2α- CHOP and IRE1α-ASK1-JNK Signaling Routes

Volume:20
Yingjuan Yang, Yana Liu, Yanhua Zhang, Wei Ji, Lan Wang and Shao Chin Lee*

Anticancer Activity Assessment and DNA Binding Properties of Two Binuclear Platinum (II) Complexes using Spectroscopic and Molecular Simulation Approaches

Volume:20
M. Mehdi Alavianmehr, Abolfazal Ashrafi*, Reza Yousefi, Mohsen G. Haghighi, Samira S. Abolmaali, Mohammad N.S. Rad and Ali A. Moosavi-Movahedi

Natural Products: Implication in Cancer Prevention and Treatment through Modulating Various Biological Activities

Volume:20
Shehwaz Anwar, Ahmad Almatroudi, Mohammed A. Alsahli, Masood A. Khan, Amjad A. Khan and Arshad H. Rahmani*

Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents

Volume:20
Swati Pawar, Kapil Kumar, Manish K. Gupta and Ravindra K. Rawal*

HCA587 protein vaccine induces specific antitumor immunity mediated by CD4+ T-cells expressing granzyme B in a mouse model of melanoma

Volume:20
Weiming Yang, Weiheng Zhang, Xiaozhong Wang, Liming Tan, Hua Li, Jiemin Wu, Qiong Wu, Wanlei Sun, Juanjuan Chen* and Yanhui Yin

In Vivo Biological Evaluation of Ethyl 4-(7-hydroxy-4-methyl-2-oxoquinolin-1-ylamino)-coumarin-3-carboxylate as Antitumor Agent

Volume:20
Faten Zahran Mohammed, Youstina William Rizzk*, Moustafa Salaheldin Abdelhamid and Ibrahim Mohey El-Deen

Apoptotic Effects of N-(2-hydroxyphenyl)-2-propylpentanamide on U87-MG and U-2 OS Cells and Antiangiogenic Properties

Volume:20
Paola Castillo-Juárez, Sebastián C. Sanchez, Alma D. Chávez-Blanco*, Humberto Mendoza-Figueroa and José Correa-Basurto

New Selenonapthaquinone-Based Copper (II) Complexes as the Next- Generation Photochemotherapeutic Agents

Volume:20
Longjam R. Devi, Md. Kausar Raza, Dulal Musib and Mithun Roy*

Novel Dihydropyrimidinone-Derived Selenoesters as Potential Cytotoxic Agents to Human Hepatocellular Carcinoma: Molecular docking and DNA Fragmentation

Volume:20
Jean C. Benassi, Flavio A.R. Barbosa, Valdelúcia M.A.S. Grinevicius, Fabiana Ourique, Daniela Coelho, Karina B. Felipe, Antônio L. Braga, Danilo W. Filho and Rozangela C. Pedrosa*

Prospective Anti-cancer Agents: A Recent Update on Drug Repurposing

Volume:20
Anjali S. Sabale, Unnati M. Patel, Ankita A. Gorhe, Vinayak R. Bodhankar, Mahesh N. Shinde, Gaurav A. Sonawane, Hitesh S. Raotole, Rohit Y. Pande and Abhijeet D. Kulkarni*

Antibody Based Targeted Interventions for the Diagnosis and Treatment of Skin Cancers.

Volume:20
Suresh Madheswaran, Neelakshi Mungra, Fleury A.N. Biteghe, Jean De la Croix Ndong, Afolake T. Arowolo, Henry A. Adeola, Dharanidharan Ramamurthy, Krupa Naran, Nonhlanhla P. Khumalo and Stefan Barth*

Elucidation of S-Allylcysteine Role in Inducing Apoptosis by Inhibiting PD-L1 Expression in Human Lung Cancer Cells

Volume:20
Fahad Khan, Pratibha Pandey*, Rashmi Mishra, Mohd. Arif, Ambuj Kumar, Asif Jafri and Rupa Mazumder

Anticancer Active Heterocyclic Chalcones: Recent Developments

Volume:20
Prasad Dandawate, Khursheed Ahmed, Subhash Padhye, Aamir Ahmad* and Bernhard Biersack

Exploring the Role of Phytochemicals as Potent Natural Photosensitizers in Photodynamic Therapy

Volume:20
Giftson J. Senapathy, Blassan P. George and Heidi Abrahamse*

Therapeutic Monoclonal Antibodies in Clinical Practice Against Cancer

Volume:20
Navgeet Kaur*, Anju Goyal and Rakesh K. Sindhu

Implication of Prophetic Variables and Their Impulsive Interplay in CA Prostate Patients Experiencing Osteo-Metastasis

Volume:20
Muhammad Abdul Basit Ashraf, Ayesha Zahid, Shazia Ashraf, Sulayman Waquar, Saima Iqbal and Arif Malik*

Design, Synthesis, Molecular Docking and Anticancer Evaluation of Pyrazole Linked Pyrazoline Derivatives with Carbothioamide tail as EGFR Kinase Inhibitors

Volume:20
Farah Nawaz, Ozair Alam*, Ahmad Perwez, Moshahid A. Rizvi, Mohd. Javed Naim, Nadeem Siddiqui, Jannat ul Firdaus, Shakilur Rahman, Mukund Jha and Aadil A. Sheikh

Serum Carboxypeptidase N1 Serves as a Potential Biomarker Complementing CA15-3 for Breast Cancer

Volume:20
Ranliang Cui, Chaomin Wang, Qi Zhao, Yichao Wang and Yueguo Li*

The Anti-Breast Cancer Effects of Green-Synthesized Zinc Oxide Nanoparticles Using Carob Extract

Volume:20
Vahid Pouresmaeil*, Shaghayegh Haghighi, Asieh S. Raeisalsadati, Ali Neamati and Masoud Homayouni-Tabrizi

Thieno[2,3-d]pyrimidin-4(3H)-one Derivatives of Benzimidazole as Potential Anti-Breast Cancer (MDA-MB-231, MCF-7) Agents.

Volume:20
Stefan Dimov, Anelia Ts. Mavrova*, Denitsa Yancheva, Biliana Nikolova and Iana Tsoneva

Anti-Angiogenetic Agents from the Sea: A New Potential Preventive and Therapeutic Wave?

Volume:20
Maria A. Gammone*, Antonella Danese and Nicolantonio D’Orazio

Aromatase Inhibitors for the Treatment of Breast Cancer: A Journey from the Scratch

Volume:20
Pooja Ratre, Keerti Mishra, Amit Dubey, Amber Vyas, Akhlesh Jain and Suresh Thareja*

Encapsulation of Imatinib in Targeted KIT-5 Nanoparticles for Reducing its Cardiotoxicity and Hepatotoxicity

Volume:20
Jaleh Varshosaz*, Saeedeh Fardshouraki, Mina Mirian, Leila Safaeian, Setareh Jandaghian and Somayeh Taymouri

llncRNAs as Potential Targets in Small Cell Lung Cancer: Myc Dependent Regulation

Volume:20
Onur Tokgun*, Pervin E. Tokgun, Kubilay Inci and Hakan Akca

Synthesis and Apoptotic Activities of New 2(3H)-benzoxazolone Derivatives in Breast Cancer Cells

Volume:20
Emine Erdag, Eda Becer, Yusuf Mulazim, H. Seda Vatansever, Hilal Kabadayı and Banu Kesanli*

Pulsatilla Saponin A Induces Apoptosis and Differentiation of Myeloma Cells

Volume:20
Bibo Ye, Yingying Zhou, Yanli Liu, Xuewei Li, Tianyu Li and Xiaofei Qi*

Proapoptotic Effects of triazol-1,4-Naphthoquinones Involve Intracellular ROS Production and MAPK/ERK Pathway in Human Leukemia Cells

Volume:20
Tangbadioa H. Coulidiati, Bruna B. Dantas, Glaucia V. Faheina-Martins, Enéas Ricardo de Morais Gomes, Juan C.R. Gonçalves* and Demetrius A. Machado de Araújo

linc01559 Served as a Potential Oncogene and Promoted Resistance of Hepatocellular Carcinoma to Oxaliplatin by Directly Sponging miR-6783-3p

Volume:20
Shunbin Dong, Ying Fu, Kaibo Yang, Xing Zhang, Runchen Miao, Yunxiang Long and Chang Liu*

Combination of Salinomycin and AZD3463 Reveals Synergistic Effect on Reducing the Viability of T98G Glioblastoma Cells

Volume:20
Aycan Asik, Neslihan P.O. Ay, Bakiye G. Bagca, Hasan O. Caglar, Cumhur Gunduz and Cigir B. Avci*

New Hybrid Scaffolds Based on Carbazole-Chalcones as Potent Anticancer Agents

Volume:20
Faisal Rashid, Sumera Zaib, Aliya Ibrar, Syeda Abida Ejaz, Aamer Saeed, Jamshed Iqbal and Imtiaz Khan*

SUV39H1-Mediated DNMT1 is Participated in the Epigenetic Regulation of Smad3 in Cervical Cancer

Volume:20
Li Zhang, Sijuan Tian, Minyi Zhao, Ting Yang, Shimin Quan, Lihua Song and Xiaofeng Yang*

Interaction of a Vanadyl Schiff Base Complex with DNA and BSA: A Combination of Experimental and Computational Studies

Volume:20
Hamid B. Aliabad, Maryam Mohamadi, Soudeh K. Falahati-Pour, Mohamad R. Hajizadeh, Danial Abdollahdokht, Mohammad H. Nematollahi and Mehdi Mahmoodi*

Fused and Substituted Pyrimidine Derivatives as a Profound Anticancer Agent

Volume:20
Nahid Abbas*, Gurubasavaraja S.P. Matada, Prasad S. Dhiwar, Shilpa Patel and Giles Devasahayam

Design, Synthesis, In Silico and In Vitro Evaluation of Novel Pyrimidine Derivatives as EGFR Inhibitors

Volume:20
Gurubasavaraja S.P. Matada*, Nahid Abbas, Prasad S. Dhiwar, Rajdeep Basu and Giles Devasahayam

ATF4, DLX3, FRA1, MSX2, C/EBP-ζ, and C/EBP‐α Shape the Molecular Basis of Therapeutic Effects of Zoledronic Acid in Bone Disorders

Volume:20
Faroogh Marofi , Jalal Choupani , Saeed Solali , Ghasem Vahedi , Ali Hassanzadeh , Tohid Gharibi and Majid Farshdousti Hagh*

Discovery of a Highly Potent and Novel Gambogic Acid Derivative as an Anticancer Drug Candidate

Volume:20
Huiping Ling, Hong Li, Meijun Chen, Baolong Lai, Haiming Zhou, Hui Gao, Jiangye Zhang, Yan Huang and Yiwen Tao*

Recent Development of Copolymeric Nano-Drug Delivery System for Paclitaxel

Volume:20
Shiyu Chen, Zhimei Song and Runliang Feng*

Anlotinib Inhibits Cell Proliferation, Migration and Invasion via Suppression of c-met Pathway and Activation of ERK1/2 Pathway in H446 Cells

Volume:20
Xiali Tang, Ying Zheng, Demin Jiao, Jun Chen, Xibang Liu, Shan Xiong and Qingyong Chen*

Andrographolide Inhibits Proliferation of Colon Cancer SW-480 Cells via Downregulating Notch Signaling Pathway.

Volume:20
Imran Khan, Sadaf Mahfooz, Mohd Saeed, Irfan Ahmad and Irfan A. Ansari*

Evaluation of Cytotoxic and Tyrosinase Inhibitory Activities of 2-phenoxy(thiomethyl) pyridotriazolopyrimidines: In Vitro and Molecular Docking Studies

Volume:20
Hatem A. Abuelizz*, El Hassane Anouar, Mohamed Marzouk, Mizaton H. Hasan, Siti R. Saleh, Adi Ahudhaif, Khalid A. Alburikan and Rashad Al-Salahi

New Insight into Triple-Negative Breast Cancer Therapy: The Potential Roles of Endoplasmic Reticulum Stress and Autophagy Mechanisms

Volume:20
Milad Ashrafizadeh, Reza Mohammadinejad, Shima Tavakol, Zahra Ahmadi and Amihossein Sahebkar*

Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway

Volume:20
Xin Lin, Babu Gajendran, Krishnapriya M. Varier, Wuling Liu, Jingrui Song, Qing Rao, Chunlin Wang, Jianfei Qiu, Wei Ni, XuJie Qin, Min Wen, Haiyang Liu and Yanmei Li*

Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid

Volume:20
Agnieszka Siebert, Milena Deptuła, Mirosława Cichorek, Anna Ronowska, Grzegorz Cholewiński* and Janusz Rachon

The Tumor Suppressor Role of the Ras Association Domain Family 10

Volume:20
Yulong Hou, Shuofeng Li, Wei Du, Hailong Li and Rumin Wen*

Synthesis and in vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4-Thiazolidinediones as Potential Anticancer Agents

Volume:20
Upasana Yadav, Yogesh Vanjari, Kritika Laxmikeshav, Ramya Tokala, Praveen Kumar Niggula, Manoj Kumar, Venu Talla, Ahmed Kamal and Nagula Shankaraiah*

Bestowal of Quinazoline Scaffold in Anticancer Drug Discovery

Volume:20
Rina Das, Dinesh K. Mehta and Meenakshi Dhanawat*

Biogenic Silver and Zero-Valent Iron Nanoparticles by Feijoa: Biosynthesis, Characterization, Cytotoxic, Antibacterial and Antioxidant Activities

Volume:20
Zahra Hashemi, Mohammad A. Ebrahimzadeh*, Pouria Biparva, Sobhan Mortazavi-Derazkola, Hamidreza Goli, Fereshteh Sadeghian, Mostafa Kardan and Alireza Rafiei

Anticancer Perspectives on the Fungal-Derived Polyphenolic Hispolon

Volume:20
Muhammad T. Islam, Eunus S. Ali, Ishaq N. Khan, Subrata Shaw, Shaikh Jamal Uddin, Razina Rouf, Shrabanti Dev, Seyed S.S. Saravi, Niranjan Das, Swati Tripathi, Santosh U. Yele, Asish K. Das, Jamil A. Shilpi, Siddhartha K. Mishra and Mohammad S. Mubarak*

Evaluation of a New 99mTc-labeled GnRH Analogue as a Possible Imaging Agent for Prostate Cancer Detection

Volume:20
Arezou M. Farahani, Fariba Maleki, Nourollah Sadeghzadeh*, Saeid Abediankenari, Seyed M. Abedi and Mostafa Erfani