Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Editor-in-Chief

Simone Carradori
Department of Pharmacy
“G. d’Annunzio” University of Chieti-Pescara
Chieti
(Italy)

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Volume: 18 Issue: 11, September 2019



Meet Our Regional Editor free to download

Volume:18   Issue: 11
Pp: 1507-1507
Isao Okazaki
DOI: 10.2174/187152061811190128115045
Published on: 27 January, 2019



Computational Study of the Binding Modes of Diverse DPN Analogues on Estrogen Receptors (ER) and the Biological Evaluation of a New Potential Antiestrogenic Ligand

Volume:18   Issue: 11
Pp: 1508-1520
M. Martinez-Archundia*, J.B. García-Vázquez, B. Colin-Astudillo, M. Bello, B. Prestegui-Martel, A. Chavez-Blanco, A. Dueñas-González, M.J. Fragoso-Vázquez, J. Mendieta-Wejebe, E. Abarca-Rojano, D. Ordaz-Rosado, R. García-Becerra, D. Castillo-Bautista and J. Correa Basurto
DOI: 10.2174/1871520618666171129152953
Published on: 29 November, 2017




Determination of the Apoptotic Effect and Molecular Docking of Benzamide Derivative XT5 in K562 Cells

Volume:18   Issue: 11
Pp: 1521-1530
Tulin Ozkan*, Yalda Hekmatshoar*, Tugba Ertan-Bolelli, Andry N. Hidayat, Meral Beksac, Esin Aki-Yalcin, Ismail Yalcin and Asuman Sunguroglu
DOI: 10.2174/1871520618666171229222534
Published on: 29 December, 2017




Synthesis and Biological Evaluation of Novel Triazoles Linked 7-hydroxycoumarin as Potent Cytotoxic Agents

Volume:18   Issue: 11
Pp: 1531-1539
Saleem Farooq*, Aashiq Hussain, Mushtaq A. Qurishi, Abid Hamid* and S. Koul
DOI: 10.2174/1871520618666171229222956
Published on: 29 December, 2017




Exploring the Lapse in Druggability: Sequence Analysis, Structural Dynamics and Binding Site Characterization of K-RasG12C Variant, a Feasible Oncotherapeutics Target

Volume:18   Issue: 11
Pp: 1540-1550
Emmanuel A. Adeniji, Fisayo A. Olotu and Mahmoud E.S. Soliman*
DOI: 10.2174/1871520618666180718110231
Published on: 18 July, 2018




Novel Anthraquinone Derivatives as Dual Inhibitors of Topoisomerase 2 and Casein Kinase 2: In Silico Studies, Synthesis and Biological Evaluation on Leukemic Cell Lines

Volume:18   Issue: 11
Pp: 1551-1562
Abbas Kabir, Kalpana Tilekar, Neha Upadhyay and C.S. Ramaa*
DOI: 10.2174/1871520618666180423111309
Published on: 23 April, 2018




Pinocembrin-Enriched Fractions of Elytranthe parasitica (L.) Danser Modulates Apoptotic and MAPK Cellular Signaling in HepG2 Cells

Volume:18   Issue: 11
Pp: 1563-1572
Nimmy Kumar, Akhila H. Shrungeswara, Sanchari B. Mallik, Subhankar Biswas, Jesil Mathew , Krishnadas Nandakumar, Jessy Mathew and Richard Lobo*
DOI: 10.2174/1871520618666180911112127
Published on: 11 September, 2018




Peniciketal A, A Novel Spiroketal Compound, Exerts Anticancer Effects by Inhibiting Cell Proliferation, Migration and Invasion of A549 Lung Cancer Cells

Volume:18   Issue: 11
Pp: 1573-1581
Xue Gao, Yuming Zhou, Xiaoqi Zheng, Hongliu Sun, Jing Zhang, Weizhong Liu* and Xiaohong Pan*
DOI: 10.2174/1871520618666180604090802
Published on: 03 June, 2018




Bursal Hexapeptide, A Potential Immunomodulator, Inhibits Tumor Cells Proliferation via p53 Signaling Pathway

Volume:18   Issue: 11
Pp: 1582-1588
Cong Zhang, Jiangfei Zhou, Shengnan Li, Kairui Cai, Xiangling Guo, Chengshui Liao* and Chen Wang*
DOI: 10.2174/1871520618666180604094618
Published on: 03 June, 2018




Novel Nicotinonitrile Derivatives Bearing Imino Moieties Enhance Apoptosis and Inhibit Tyrosine Kinase

Volume:18   Issue: 11
Pp: 1589-1598
Maher A. El-Hashash, Eman A. El-Bordany, Magda I. Marzouk, Abeer M. El-Naggar, Tarek M.S. Nawar and Wael M. El-Sayed*
DOI: 10.2174/1871520618666180510112614
Published on: 10 May, 2018




Lichen Acids May Be Used as A Potential Drug For Cancer Therapy; by Inhibiting Mitochondrial Thioredoxin Reductase Purified From Rat Lung

Volume:18   Issue: 11
Pp: 1599-1605
Ilknur Ozgencli, Harun Budak*, Mehmet Ciftci and Mustafa Anar
DOI: 10.2174/1871520618666180525095520
Published on: 24 May, 2018




Synthesis and Evaluation of a Series of 1,3,4-Thiadiazole Derivatives as Potential Anticancer Agents

Volume:18   Issue: 11
Pp: 1606-1616
Mehlika D. Altıntop*, Belgin Sever, Ahmet Özdemir, Sinem Ilgın, Özlem Atlı, Gülhan Turan-Zitouni and Zafer A. Kaplancıklı
DOI: 10.2174/1871520618666180509111351
Published on: 09 May, 2018




TPEN Exerts Antitumor Efficacy in Murine Mammary Adenocarcinoma Through an H2O2 Signaling Mechanism Dependent on Caspase-3

Volume:18   Issue: 11
Pp: 1617-1628
Viviana Soto-Mercado, Miguel Mendivil-Perez, Claudia Urueña-Pinzon, Susana Fiorentino, Carlos Velez-Pardo and Marlene Jimenez-Del-Rio*
DOI: 10.2174/1871520618666180426111520
Published on: 26 April, 2018




Selection of a GPER1 Ligand via Ligand-based Virtual Screening Coupled to Molecular Dynamics Simulations and Its Anti-proliferative Effects on Breast Cancer Cells

Volume:18   Issue: 11
Pp: 1629-1638
Alberto Martínez-Muñoz, Berenice Prestegui-Martel, David Méndez-Luna, Manuel J. Fragoso-Vázquez*, José Rubén García-Sánchez, Martiniano Bello, Marlet Martínez-Archundia, Alma Chávez-Blanco, Alfonso Dueñas-González, Irene Mendoza-Lujambio, José Trujillo-Ferrara and José Correa-Basurto*
DOI: 10.2174/1871520618666180510121431
Published on: 10 May, 2018




Synthesis and Anticancer Activity of 9-O-Pyrazole Alkyl Substituted Berberine Derivatives

Volume:18   Issue: 11
Pp: 1639-1648
Daipeng Xiao, Fen He, Dongming Peng, Min Zou, Junying Peng, Pan Liu, Yanfei Liu* and Zhenbao Liu*
DOI: 10.2174/1871520618666180717121208
Published on: 17 July, 2018