Anti-Cancer Agents in Medicinal Chemistry

Anti-Cancer Agent-Induced Nephrotoxicity

Volume:14   Issue: 7
Pp: 921-927
Hirotaka Fukasawa, Ryuichi Furuya, Hideo Yasuda, Tatsuo Yamamoto, Akira Hishida and Masatoshi Kitagawa
DOI: 10.2174/1871520614666140127105809
Published on: 26 January, 2014

EGFRIndb: Epidermal Growth Factor Receptor Inhibitor Database

Volume:14   Issue: 7
Pp: 928-935
Inderjit S. Yadav, Harinder Singh, Mohd. Imran Khan, Ashok Chaudhury, G.P.S. Raghava and Subhash M. Agarwal
DOI: 10.2174/1871520614666140323203140
Published on: 23 March, 2014

Betulinic Acid as a Potent and Complex Antitumor Phytochemical: A Minireview

Volume:14   Issue: 7
Pp: 936-945
Dorina Gheorgheosu, Oana Duicu, Cristina Dehelean, Codruta Soica and Danina Muntean
DOI: 10.2174/1871520614666140223192148
Published on: 23 February, 2014

Novel Action and Mechanism of Auranofin in Inhibition of Vascular Endothelial Growth Factor Receptor-3-Dependent Lymphangiogenesis

Volume:14   Issue: 7
Pp: 946-954
Xiaodong Chen, Huanjiao Jenny Zhou, Qunhua Huang, Lin Lu and Wang Min
DOI: 10.2174/1871520614666140610102651
Published on: 09 June, 2014

Activation of Integrin β1 Mediates the Increased Malignant Potential of Ovarian Cancer Cells Exerted by Inflammatory Cytokines

Volume:14   Issue: 7
Pp: 955-962
Zongyuan Yang, Xiaoshui Zhou, Yi Liu, Cheng Gong, Xiao Wei, Taoran Zhang, Ding Ma and Qinglei Gao
DOI: 10.2174/1871520614666140613123108
Published on: 13 June, 2014

Chalcone-Coumarin Derivatives as Potential Anti-Cancer Drugs: An in vitro and in vivo Investigation

Volume:14   Issue: 7
Pp: 963-974
Vincent Jamier, Wioleta Marut, Sergio Valente, Christiane Chereau, Sandrine Chouzenoux, Carole Nicco, Herve Lemarechal, Bernard Weill, Gilbert Kirsch, Claus Jacob and Frederic Batteux
DOI: 10.2174/1871520613666131224124445
Published on: 24 December, 2013

Sesamol Ameliorates Cyclophosphamide-Induced Hepatotoxicity by Modulating Oxidative Stress and Inflammatory Mediators

Volume:14   Issue: 7
Pp: 975-983
S. Jnaneshwari, M. Hemshekhar, R.M. Thushara, M. Shanmuga Sundaram, M. Sebastin Santhosh, K. Sunitha, R.L. Shankar, K. Kemparaju and K.S. Girish
DOI: 10.2174/1871520613666131224123346
Published on: 24 December, 2013

Three Amino Acid Derivatives of Valproic Acid: Design, Synthesis, Theoretical and Experimental Evaluation as Anticancer Agents

Volume:14   Issue: 7
Pp: 984-993
Gabriela R. Luna-Palencia, Federico Martinez-Ramos, Ismael Vasquez-Moctezuma, Manuel Jonathan Fragoso-Vazquez, Jessica Elena Mendieta-Wejebe, Itzia I. Padilla-Martínez, Yudibeth Sixto-Lopez, David Mendez-Luna, Jose Trujillo-Ferrara, Marco A. Meraz-Rios, Yadira Fonseca-Sabater and Jose Correa-Basurto
DOI: 10.2174/1871520614666140127113218
Published on: 26 January, 2014

Synthesis and Biological Evaluation of 3-Substituted-4-(4-methylthio phenyl)-1HPyrrole Derivatives as Potential Anticancer Agents

Volume:14   Issue: 7
Pp: 994-1002
Lan Lan, Weixi Qin, Xiaoping Zhan, Zenglu Liu and Zhenmin Mao
DOI: 10.2174/1871520613666131224123823
Published on: 24 December, 2013

Anticancer Activity of New Compounds Using Benzimidazole as a Scaffold

Volume:14   Issue: 7
Pp: 1003-1018
Mohd Rashid, Asif Husain, Mohammad Shaharyar and Mohd Sarafroz
DOI: 10.2174/1871520614666140509153021
Published on: 09 May, 2014

Modeling Study of Phenylsulfonylfuroxan Derivatives as P-gp Inhibitors: A Combined Approach of CoMFA, CoMSIA and HQSAR

Volume:14   Issue: 7
Pp: 1019-1030
Changdev G. Gadhe, Anand Balupuri, Pavithra K. Balasubramanian and Seung Joo Cho
DOI: 10.2174/18715206113136660335
Published on: 19 September, 2013

Trifluoroibuprofen Inhibits α-Methylacyl Coenzyme A Racemase (AMACR/P504S), Reduces Cancer Cell Proliferation and Inhibits in vivo Tumor Growth in Aggressive Prostate Cancer Models

Volume:14   Issue: 7
Pp: 1031-1041
Claudio Festuccia, Giovanni Luca Gravina, Andrea Mancini, Paola Muzi, Ernesto Di Cesare, Ralph Kirk, Matthew Smith, Shaun Hughes, Robert Gibson, Lu-Yun Lian, Enrico Ricevuto and Andrew J. Carnell
DOI: 10.2174/1871520614666140327152607
Published on: 27 March, 2014

Hypersensitivity to Aurora Kinase Inhibitors in Cells Resistant against Platinum- Containing Anticancer Agents

Volume:14   Issue: 7
Pp: 1042-1050
Masaki Akiyama, Hiroto Izumi, Ke-Yong Wang, Takahiro Yamaguchi, Akihiro Kuma, Noriaki Kitamura, Yoshikazu Harada, Ryoichi Oya, Koji Yamaguchi, Yoshiko Iwai and Kimitoshi Kohno
DOI: 10.2174/1871520614666140207154351
Published on: 07 February, 2014

ent-Kaurane Diterpenoids from Croton tonkinensis Induce Apoptosis in Colorectal Cancer Cells through the Phosphorylation of JNK Mediated by Reactive Oxygen Species and Dual-Specificity JNK Kinase MKK4

Volume:14   Issue: 7
Pp: 1051-1061
Phuong Thien Thuong, Nguyen Minh Khoi, Saho Ohta, Shinichiro Shiota, Hironori Kanta, Kenji Takeuchi and Fumiaki Ito
DOI: 10.2174/1871520614666140127111407
Published on: 26 January, 2014