Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Editor-in-Chief

Simone Carradori
Department of Pharmacy
“G. d’Annunzio” University of Chieti-Pescara
Chieti
(Italy)

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Editorial (Thematic Issue: Green Anti-Cancer Agents and Ayur-Biotechnology: A smart approach towards improving R&D productivity.) free to download

Volume:13   Issue: 10
Pp: 1467-1468
Krishnaswami S. Raja
DOI: 10.2174/18715206113139990102
Published on: 06 December, 2013

First Ayurvedic Approach Towards Green Drugs: Anti Cervical Cancer-Cell Properties of Clerodendrum viscosum Root Extract

Volume:13   Issue: 10
Pp: 1469-1476
Chong Sun, Swami Nirmalananda, Charles E. Jenkins, Shawon Debnath, Rema Balambika, Jimmie E. Fata and Krishnaswami S. Raja
DOI: 10.2174/18715206113139990138
Published on: 06 December, 2013

Betulin-Betulinic Acid Natural Product Based Analogs as Anti-Cancer Agents

Volume:13   Issue: 10
Pp: 1477-1499
Subash C. Jonnalagadda, Michael A. Corsello and Christopher E. Sleet
DOI: 10.2174/18715230113129990094
Published on: 06 December, 2013

Chemoprevention of Skin Cancer: Effect of Lawsonia inermis L. (Henna) Leaf Powder and its Pigment Artifact, Lawsone in the Epstein- Barr Virus Early Antigen Activation Assay and in Two-Stage Mouse Skin Carcinogenesis Models

Volume:13   Issue: 10
Pp: 1500-1507
Govind J. Kapadia, G. Subba Rao, Rajagopalan Sridhar, Eiichiro Ichiishi, Midori Takasaki, Nobutaka Suzuki, Takao Konoshima, Akira Iida and Harukuni Tokuda
DOI: 10.2174/18715206113139990096
Published on: 06 December, 2013

Curcumin Potentiates The Ability of Sunitinib to Eliminate the VHL-lacking Renal Cancer Cells 786-O: Rapid Inhibition of Rb Phosphorylation as a Preamble to Cyclin D1 Inhibition

Volume:13   Issue: 10
Pp: 1508-1513
Priya Ranjan Debata, Sultana Begum, Anita Mata, Oksana Genzer, Morton J. Kleiner, Probal Banerjee and Mario R. Castellanos
DOI: 10.2174/18715206113139990093
Published on: 06 December, 2013

Stereoselective Synthesis of Pyroglutamate Natural Product Analogs from α- Aminoacids and their Anti-Cancer Evaluation

Volume:13   Issue: 10
Pp: 1514-1530
Srinivas Tekkam, Mohammad A. Alam, Matthew J. Just, Steven M. Berry, Joseph L. Johnson, Subash C. Jonnalagadda and Venkatram R. Mereddy
DOI: 10.2174/18715206113139990097
Published on: 06 December, 2013

Dendrimer-Curcumin Conjugate: A Water Soluble and Effective Cytotoxic Agent Against Breast Cancer Cell Lines

Volume:13   Issue: 10
Pp: 1531-1539
Shawon Debnath, Darin Saloum, Sukanta Dolai, Chong Sun, Saadyah Averick, Krishnaswami Raja and Jimmie E. Fata
DOI: 10.2174/18715206113139990139
Published on: 06 December, 2013

Garcinia Benzophenones Inhibit the Growth of Human Colon Cancer Cells and Synergize with Sulindac Sulfide and Turmeric

Volume:13   Issue: 10
Pp: 1540-1550
Linda Saxe Einbond, Jason Mighty, Ryota Kashiwazaki, Mario Figueroa, Filza Jalees, Ulyana Munoz Acuna, Onica LeGendre, David A. Foster and Edward J. Kennelly
DOI: 10.2174/18715206113139990095
Published on: 06 December, 2013

Editorial: Plant Derived Secondary Metabolites as Anti-Cancer Agents promotion: free to download

Volume:13   Issue: 10
Pp: 1551-1551
Diwan S. Rawat and Ram Singh
DOI: 10.2174/187152061310131206154445
Published on: 06 December, 2013

Recent Development in Targeting PI3K-Akt-mTOR Signaling for Anticancer Therapeutic Strategies

Volume:13   Issue: 10
Pp: 1552-1564
Asif Khurshid Qazi, Aashiq Hussain, Abid Hamid, Yasrib Qurishi, Rabiya Majeed, Mudassier Ahmad, Rauf Ahmad Najar, Javeed Ahmad Bhat, Shashank Kumar Singh, Mohmmad Afzal Zargar, Shakir Ali and Ajit Kumar Saxena
DOI: 10.2174/1871520613666131125123241
Published on: 06 December, 2013

Cinnamaldehyde-Induced Apoptosis in Human Hepatoma PLC/PRF/5 Cells Involves the Mitochondrial Death Pathway and is Sensitive to Inhibition by Cyclosporin A and z-VAD-fmk

Volume:13   Issue: 10
Pp: 1565-1574
Liang-Tzung Lin, Chen-Jei Tai, Shun-Pang Chang, Jin-Liang Chen, Shu-Jing Wu and Chun-Ching Lin
DOI: 10.2174/18715206113139990144
Published on: 06 December, 2013

Myricetin Induces Apoptosis in HepG2 Cells Through Akt/p70S6K/Bad Signaling and Mitochondrial Apoptotic Pathway

Volume:13   Issue: 10
Pp: 1575-1581
Xiao-Hong Zhang, Shi-Yong Chen, Lin Tang, Ying-Zhuo Shen, Lin Luo, Chen-Wei Xu, Qiong Liu and Duo Li
DOI: 10.2174/1871520613666131125123059
Published on: 06 December, 2013

Natural Compounds with Cell Growth Inhibitory Activity in Human Tumor Cell Lines

Volume:13   Issue: 10
Pp: 1582-1589
Cristiane M. Cazal, Kantima Choosang, Vanessa Gisele P. Severino, João B. Fernandes, Maria Fátima G. F. da Silva, Paulo C. Vieira, Maria S. J. Nascimento, Gabriela M. Almeida, M. Helena Vasconcelos, Pannee Pakkong and Madalena M. M. Pinto
DOI: 10.2174/1871520613666131125122857
Published on: 06 December, 2013

Synthesis and Biological Evaluation of Diaryl Ether Linked DC-81 Conjugates as Potential Antitumor Agents

Volume:13   Issue: 10
Pp: 1590-1600
Ahmed Kamal, A. Viswanath, M. Janaki Ramaiah, J. N.S.R.C. Murty, Farheen Sultana, E. Vijaya Bharathi, G. Ramakrishna, Pranjal Sarma, A. Lavanya, S. N.C.V.L. Pushpavalli and Manika pal Bhadra
DOI: 10.2174/1871520613666131125122408
Published on: 06 December, 2013

Differential Effects of Polyphenols on Proliferation and Apoptosis in Human Myeloid and Lymphoid Leukemia Cell Lines open access plus

Volume:13   Issue: 10
Pp: 1601-1613
Amani A Mahbub, Christine L. Le Maitre, Sarah L. Haywood-Small, Gordon J. McDougall, Neil A. Cross and Nicola Jordan-Mahy
DOI: 10.2174/18715206113139990303
Published on: 06 December, 2013

Discovery and Hit to Lead Optimization of Novel Combretastatin A-4 Analogues: Dependence of C-Linker Length and Hybridization

Volume:13   Issue: 10
Pp: 1614-1635
Olivier Provot, Abdallah Hamze, Jean-François Peyrat, Jean-Daniel Brion and Mouad Alami
DOI: 10.2174/187152061310131206162302
Published on: 06 December, 2013

In Silico Study of Desmosdumotin as an Anticancer Agent: Homology Modeling, Docking and Molecular Dynamics Simulation Approach

Volume:13   Issue: 10
Pp: 1636-1644
Changdev G. Gadhe, Gugan Kothandan and Seung Joo Cho
DOI: 10.2174/18715206113139990302
Published on: 06 December, 2013

Effects of Limonoid Cedrelone on MDA-MB-231 Breast Tumor Cells in vitro

Volume:13   Issue: 10
Pp: 1645-1653
Angelina M. Fuzer, Júlio César C. Filho, Amanda B. Becceneri, Damiana A. dos Santos, Maria Fátima das G. F. da Silva, Paulo C. Vieira, João B. Fernandes, Heloisa S. Selistre-de-Araujo, Cristiane M. Cazal and Márcia R. Cominetti
DOI: 10.2174/18715206113139990314
Published on: 06 December, 2013

ACKNOWLEDGEMENTS TO THE REVIEWERS promotion: free to download

Volume:13   Issue: 10
Pp: 1654-1655

DOI: 10.2174/187152061310131206165254
Published on: 06 December, 2013