Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Editor-in-Chief

Simone Carradori
Department of Pharmacy
“G. d’Annunzio” University of Chieti-Pescara
Chieti
(Italy)

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Editor's Choice

Synthesis of 1H-1,2,3-Triazole-Linked Quinoline-Isatin Molecular Hybrids as Anti-Breast Cancer and Anti-Methicillin-Resistant Staphylococcus aureus (MRSA) Agents

Volume: 21   Issue: 10
Pp: 1228-1239
Paul Awolade, Nosipho Cele, Oluwakemi Ebenezer, Nagaraju Kerru, Lalitha Gummidi, Liang Gu, Gabriella Palma, Mandeep Kaur and Parvesh Singh*
DOI: 10.2174/1871520620666200929153138

On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7)

Volume: 21   Issue: 9
Pp: 1172-1182
Celisnolia M. Leite*, João Honorato de Araujo-Neto, Rodrigo S. Corrêa, Legna Colina-Vegas, Diego Martínez-Otero, Paulo R. Martins, Cristiane G. Silva and Alzir A. Batista*
DOI: 10.2174/1871520620666200824114816

Synthesis and Evaluation of Cytotoxic Activity of Certain Benzo[h]chromene Derivatives

Volume: 21   Issue: 8
Pp: 963-986
Samir M. Awad, Mosaad S. Mohamed, Marwa Abd El-Fattah Khodair and Rania H. Abd El-Hameed*
DOI: 10.2174/1871520620666200925103742

Recent Progress in the Development of Quinoline Derivatives for the Exploitation of Anti-Cancer Agents

Volume: 21   Issue: 7
Pp: 825-838
Ruo-Jun Man, Nasreen Jeelani, Chongchen Zhou* and Yu-Shun Yang*
DOI: 10.2174/1871520620666200516150345

Novel Dihydropyrimidinone-Derived Selenoesters as Potential Cytotoxic Agents to Human Hepatocellular Carcinoma: Molecular Docking and DNA Fragmentation

Volume: 21   Issue: 6
Pp: 703-715
Jean C. Benassi, Flavio A.R. Barbosa, Valdelúcia M.A.S. Grinevicius, Fabiana Ourique, Daniela Coelho, Karina B. Felipe, Antônio L. Braga, Danilo W. Filho and Rozangela C. Pedrosa*
DOI: 10.2174/1871520620666200728124640

Anticancer Active Heterocyclic Chalcones: Recent Developments

Volume: 21   Issue: 5
Pp: 558-566
Prasad Dandawate, Khursheed Ahmed, Subhash Padhye, Aamir Ahmad* and Bernhard Biersack*
DOI: 10.2174/1871520620666200705215722

Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid

Volume: 21   Issue: 4
Pp: 462-467
Agnieszka Siebert, Milena Deptuła, Mirosława Cichorek, Anna Ronowska, Grzegorz Cholewiński* and Janusz Rachon
DOI: 10.2174/1871520620666200516151456

Benzimidazole Derivative Ameliorates Opioid-Mediated Tolerance during Anticancer- Induced Neuropathic Pain in Mice

Volume: 21   Issue: 3
Pp: 365-371
Sana Akhtar, Muzaffar Abbas*, Komal Naeem, Muhammad Faheem, Humaira Nadeem and Amber Mehmood
DOI: 10.2174/1871520620999200818155031

Anti-Metastatic Effects of Lupeol via the Inhibition of MAPK/ERK Pathway in Lung Cancer

Volume: 21   Issue: 2
Pp: 201-206
Mital Bhatt, Mitesh Patel*, Mohd Adnan and Mandadi N. Reddy
DOI: 10.2174/1871520620666200424131548

Therapy Resistance in Cancers: Phenotypic, Metabolic, Epigenetic and Tumour Microenvironmental Perspectives

Volume: 20   Issue: 18
Pp: 2190-2206
Tasnim Zahan, Plabon K. Das, Syeda F. Akter, Rowshanul Habib, Md. Habibur Rahman, Md. Rezaul Karim* and Farhadul Islam*
DOI: 10.2174/1871520620999200730161829

Characterization of Cepharanthin Nanosuspensions and Evaluation of Their In Vitro Activity for the HepG2 Hepatocellular Carcinoma Cell Line

Volume: 20   Issue: 18
Pp: 2293-2303
Yue Zhao, Tingting Fu, Gaoke Meng, Fangxia Qiao, Yanhui Hou, Yanhua Liu and Jianhong Yang*
DOI: 10.2174/1871520620999200730170844

Histone Deacetylase Inhibitor Trichostatin A Suppresses Cell Proliferation and Induces Apoptosis by Regulating the PI3K/AKT Signalling Pathway in Gastric Cancer Cells

Volume: 20   Issue: 17
Pp: 2114-2124
Xinli An, Zekun Wei, Botian Ran, Hao Tian, Hongyu Gu, Yan Liu, Hongjuan Cui* and Shunqin Zhu*
DOI: 10.2174/1871520620666200627204857

The Anticancer Properties of Silibinin: Its Molecular Mechanism and Therapeutic Effect in Breast Cancer

Volume: 20   Issue: 15
Pp: 1787-1796
Agata Binienda, Sylwia Ziolkowska and Elzbieta Pluciennik*
DOI: 10.2174/1871520620666191220142741

Radioactive Gold Nanoparticle in Two Forms (19879Au GNPs and 99mTc-GNPs) for Lung Cancer Antiproliferative Induction and Intralesional Imaging: A Proof of Concept

Volume: 20   Issue: 14
Pp: 1648-1653
Hongwei Xu, Shengpan Jiang, Jimin Wang, Xuebing Li, Tingwei Wu, Pengfei Xu, Ralph Santos-Oliveira and Aohua Zhang*
DOI: 10.2174/1871520620666200529113818

Design, Synthesis and Biological Evaluation of Novel 1,2,5-Oxadiazol-3- Carboximidamide Derivatives as Indoleamine 2, 3-Dioxygenase 1 (IDO1) Inhibitors

Volume: 20   Issue: 13
Pp: 1592-1603
Zhifeng Xia, Yanyang Nan, Chang Liu, Guangyu Lin, Kedan Gu, Cheng Chen, Weili Zhao, Dianwen Ju and Xiaochun Dong*
DOI: 10.2174/1871520620666200604121225

Concise Synthesis of 1,1-Diarylvinyl Sulfones and Investigations on their Antiproliferative Activity via Tubulin Inhibition

Volume: 20   Issue: 12
Pp: 1469-1474
Lavanya Reddy, Suja T. Dharmabalan*, Kanakaraju Manupati, Ragini Yeeravalli, Lakshmi D. Vijay, Kavitha Donthiboina, Vadithe Lakshma Naik and Amitava Das
DOI: 10.2174/1871520620666200423075630