Abstract
The unique biological properties of Geminin, particularly as an inhibitor of DNA replication initiation, have been recognized, and this has prompted a number of investigations into this molecule to explore its potential therapeutic as well as diagnostic usefulness. This review summarizes the possibility of Geminin serving as a new molecular target in the development of new anticancer drugs.
Keywords: Geminin, Cdt1, DNA replication, Cancer cell, Peptide
Mini-Reviews in Medicinal Chemistry
Title: Geminin as A Molecular Target for the Development of New Anticancer Drugs
Volume: 6 Issue: 4
Author(s): Kenichi Yoshida
Affiliation:
Keywords: Geminin, Cdt1, DNA replication, Cancer cell, Peptide
Abstract: The unique biological properties of Geminin, particularly as an inhibitor of DNA replication initiation, have been recognized, and this has prompted a number of investigations into this molecule to explore its potential therapeutic as well as diagnostic usefulness. This review summarizes the possibility of Geminin serving as a new molecular target in the development of new anticancer drugs.
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Cite this article as:
Yoshida Kenichi, Geminin as A Molecular Target for the Development of New Anticancer Drugs, Mini-Reviews in Medicinal Chemistry 2006; 6 (4) . https://dx.doi.org/10.2174/138955706776361411
DOI https://dx.doi.org/10.2174/138955706776361411 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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