Abstract
One of the hallmarks of modern science is technically controlled experimentation. In this paper, we underline how technical developments over the last 150 years have repeatedly created new horizons in amyloid research. The main focus is on chemical and biophysical analyses of amyloid fibrils in vivo and in vitro. Investigations into mechanistic aspects of fibril formation and possible links with pathogenesis are also discussed.
Keywords: Amyloid, history, milestones, experimental method, experimental technique
Protein & Peptide Letters
Title: A Short Historical Survey of Developments in Amyloid Research
Volume: 13 Issue: 3
Author(s): Mireille Dumoulin and Reto Bader
Affiliation:
Keywords: Amyloid, history, milestones, experimental method, experimental technique
Abstract: One of the hallmarks of modern science is technically controlled experimentation. In this paper, we underline how technical developments over the last 150 years have repeatedly created new horizons in amyloid research. The main focus is on chemical and biophysical analyses of amyloid fibrils in vivo and in vitro. Investigations into mechanistic aspects of fibril formation and possible links with pathogenesis are also discussed.
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Cite this article as:
Dumoulin Mireille and Bader Reto, A Short Historical Survey of Developments in Amyloid Research, Protein & Peptide Letters 2006; 13 (3) . https://dx.doi.org/10.2174/092986606775338434
DOI https://dx.doi.org/10.2174/092986606775338434 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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