Abstract
Our understanding of biological systems has improved dramatically due to decades of exploration. This process has been accelerated even further during the past ten years, mainly due to the genome projects, new technologies such as microarray, and developments in proteomics. These advances have generated huge amounts of data describing biological systems from different aspects. Still, integrating this knowledge to reconstruct a biological system in silico has been a significant challenge for biologists, computer scientists, engineers, mathematicians and statisticians. Engineering approaches toward integrating biological information can provide many advantages and capture both the static and dynamic information of a biological system. Methodologies, documentation and project management from the engineering field can be applied. This paper discusses the process, knowledge representation and project management involved in engineering approaches used for biological information integration, mainly using software engineering as an example. Developing efficient courses to educate students to meet the demands of this interdisciplinary approach will also be discussed.
Keywords: Biological information integration, engineering, process, object-oriented
Current Bioinformatics
Title: Engineering Approaches Toward Biological Information Integration at the Systems Level
Volume: 1 Issue: 1
Author(s): Wenjin J. Zheng
Affiliation:
Keywords: Biological information integration, engineering, process, object-oriented
Abstract: Our understanding of biological systems has improved dramatically due to decades of exploration. This process has been accelerated even further during the past ten years, mainly due to the genome projects, new technologies such as microarray, and developments in proteomics. These advances have generated huge amounts of data describing biological systems from different aspects. Still, integrating this knowledge to reconstruct a biological system in silico has been a significant challenge for biologists, computer scientists, engineers, mathematicians and statisticians. Engineering approaches toward integrating biological information can provide many advantages and capture both the static and dynamic information of a biological system. Methodologies, documentation and project management from the engineering field can be applied. This paper discusses the process, knowledge representation and project management involved in engineering approaches used for biological information integration, mainly using software engineering as an example. Developing efficient courses to educate students to meet the demands of this interdisciplinary approach will also be discussed.
Export Options
About this article
Cite this article as:
Zheng J. Wenjin, Engineering Approaches Toward Biological Information Integration at the Systems Level, Current Bioinformatics 2006; 1 (1) . https://dx.doi.org/10.2174/157489306775330589
DOI https://dx.doi.org/10.2174/157489306775330589 |
Print ISSN 1574-8936 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-392X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Preface
Pharmaceutical Nanotechnology Quality of Life in Family Caregivers of Patients with Schizophrenia: A Narrative Review
Current Psychiatry Research and Reviews Inhibiting Glutathione Metabolism in Lung Lining Fluid as a Strategy to Augment Antioxidant Defense
Current Enzyme Inhibition Tiny Regulators in Viral Infection: Carving SARS-CoV-2 by miRNAs
MicroRNA Expression and Clinical Significance of SARS-CoV-2 Human Targets in Neoplastic and Non-Neoplastic Lung Tissues
Current Cancer Drug Targets Snake Venom Peptides and Low Mass Proteins: Molecular Tools and Therapeutic Agents
Current Medicinal Chemistry Medicinal Perspective of Indole Derivatives: Recent Developments and Structure-Activity Relationship Studies
Current Drug Targets Recent Approaches and Success of Liposome-Based Nano Drug Carriers for the Treatment of Brain Tumor
Current Drug Delivery Green Tea Polyphenols as Proteasome Inhibitors: Implication in Chemoprevention
Current Cancer Drug Targets Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors
Current Pharmaceutical Design Synthesis of 1,1-Dioxobenzo[b]thiophene-2-ylmethyloxycarbonyl (Bsmoc) Protected N-Methyl Amino Acids by Reduction of Bsmoc-5-Oxazolidinones and Their Use in Peptide Synthesis
Protein & Peptide Letters QSAR Studies of Some Substituted 1,3-Diaryl Propenone Derivatives as Plasmodium falciparum Growth Inhibitors
Letters in Drug Design & Discovery Recent Developments in the Synthesis of Antitumor-active Glycyrrhetinic Acid Derivatives
Mini-Reviews in Organic Chemistry Therapeutic HIV Vaccines
Current Topics in Medicinal Chemistry Anticancer Drug-Induced Immunomodulation and Cancer Therapeutics
Current Cancer Therapy Reviews A Review on Biological Activities and Chemical Synthesis of Hydrazide Derivatives
Current Medicinal Chemistry Silencing of Tumor Necrosis Factor Receptor-1 in Human Lung Microvascular Endothelial Cells Using Particle Platforms for siRNA Delivery
Current Drug Targets Functional Genomics and NMR Spectroscopy
Combinatorial Chemistry & High Throughput Screening Structure, Stability, and Electronic Feature Analyses of Substrates (Methyl Orange and Vanadium Oxide)-Surfactant (Triton X-100) Complex: A Computational Insight
Current Applied Polymer Science Association of Genetic Variation with Pneumonia
Current Respiratory Medicine Reviews