Abstract
A survey is provided on new synthetic pathways to pyrido[1,2-a]pyrimidinium, pyrido[1,2-a]pyrazinium, pyrido[1,2-c]pyrimidinium, and pyrido[1,2-b]pyridazinium systems and their partially saturated derivatives appeared during the recent years. Reaction mechanisms of these ring closure methodologies are also discussed. Some representative further transformations of these ring systems are also summarized. Thus, alkylation of olates and thiolates, ring opening reactions, photochemical transformations and flash vacuum pyrolytic reactions are reviewed.
Keywords: Claisen condensation, Stille-coupling, alkylating reagent, zwitterionic aziniumolates, quinolizinium cation, Bridgehead-nitrogen
Current Organic Chemistry
Title: Recent Advances in the Area of Pyridodiazinium Systems Containing Bridgehead-Nitrogen Atom
Volume: 10 Issue: 3
Author(s): Gyorgy Hajos
Affiliation:
Keywords: Claisen condensation, Stille-coupling, alkylating reagent, zwitterionic aziniumolates, quinolizinium cation, Bridgehead-nitrogen
Abstract: A survey is provided on new synthetic pathways to pyrido[1,2-a]pyrimidinium, pyrido[1,2-a]pyrazinium, pyrido[1,2-c]pyrimidinium, and pyrido[1,2-b]pyridazinium systems and their partially saturated derivatives appeared during the recent years. Reaction mechanisms of these ring closure methodologies are also discussed. Some representative further transformations of these ring systems are also summarized. Thus, alkylation of olates and thiolates, ring opening reactions, photochemical transformations and flash vacuum pyrolytic reactions are reviewed.
Export Options
About this article
Cite this article as:
Hajos Gyorgy, Recent Advances in the Area of Pyridodiazinium Systems Containing Bridgehead-Nitrogen Atom, Current Organic Chemistry 2006; 10 (3) . https://dx.doi.org/10.2174/138527206775473887
DOI https://dx.doi.org/10.2174/138527206775473887 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Growth and Attachment of Embryonic Stem Cell Colonies on Single Nanofibers
Micro and Nanosystems Nucleotide Binding Affects Intrinsic Dynamics and Structural Communication in Ras GTPases
Current Pharmaceutical Design Virtual Screening, Molecular Docking and <i>In silico</i> ADME-Tox Analysis for Identification of Potential Main Protease (Mpro) Enzyme Inhibitors
Anti-Infective Agents Artificial Blood: A Futuristic Dimension of Modern Day Transfusion Sciences
Cardiovascular & Hematological Agents in Medicinal Chemistry Third Wave of the COVID-19 Pandemic: Prominence of Initial Public Health Interference
Infectious Disorders - Drug Targets Mechanism of Actions of Dexamethasone Against COVID-19 Predicted by Alpha Shape Analysis of Binding Sites
Current Bioinformatics New and Old Hot Drug Targets in Tuberculosis
Current Medicinal Chemistry The Effect of Acute Hypoxia on Excitability in the Heart and the L-Type Calcium Channel as a Therapeutic Target
Current Drug Discovery Technologies Conformation and Bioactivity. Design and Discovery of Novel Antihypertensive Drugs
Current Topics in Medicinal Chemistry New Prospects for Glycopeptide Based Analgesia: Glycoside-Induced Penetration of the Blood-Brain Barrier
Current Drug Delivery Urine IL-18 is a Biomarker of Early Acute Kidney Injury (AKI)
Recent Patents on Biomarkers Optimal Sedation for the Ventilation of Critically Ill Patients
Current Respiratory Medicine Reviews Therapeutic Targeting of the Soluble Guanylate Cyclase
Current Medicinal Chemistry Safe Use of Sodium Dodecyl Sulfate (SDS) to Deactivate SARS-CoV-2: An Evidence-Based Systematic Review
Coronaviruses History and Global Status of the New Coronavirus Covid-2019 and Aspects of Previous Infections of SARS-CoV and MERS-CoV: A Systematic Review
Coronaviruses Rubiscolins - Highly Potent Peptides Derived from Plant Proteins
Mini-Reviews in Medicinal Chemistry Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management
Current Medicinal Chemistry Significant Breakthroughs in Search for Anti-Infectious Agents Derived from Erythromycin A
Current Medicinal Chemistry Common Themes in RNA Subcellular Transport, Stress Granule Formation and Abnormal Protein Aggregation
Current Chemical Biology Divergent Synthesis of Novel Dienylbenzothiazoles and Arylidenedibenzoxazepines and Evaluation of Their Antiproliferative and Cytotoxic Properties
Letters in Organic Chemistry