Abstract
Tuberculosis (TB) is a global health problem due to the lack of new drugs in the market and also due to the advent of multidrug resistant strains (MDR). This disease affects around 8 million people and kills almost 3 million people each year and it is estimated that there are 1 billion infected with TB worldwide. Due to this problem fluoroquinolones have attracted much attention as the new class of anti TB drugs due to their fewer toxic side effects, improved pharmacokinetic properties and extensive and potent activity against Grampositive and Gram-negative bacteria, including resistant strains. In this present review we report fluoroquinolones as a promising new class of anti TB.
Keywords: Tuberculosis, antibiotics, fluoroquinolones
Current Medicinal Chemistry
Title: Fluoroquinolones: An Important Class of Antibiotics Against Tuberculosis
Volume: 13 Issue: 4
Author(s): Marcus V. N. De Souza, Thatyana R. A. Vasconcelos, Mauro V. d. Almeida and Silvia H. Cardoso
Affiliation:
Keywords: Tuberculosis, antibiotics, fluoroquinolones
Abstract: Tuberculosis (TB) is a global health problem due to the lack of new drugs in the market and also due to the advent of multidrug resistant strains (MDR). This disease affects around 8 million people and kills almost 3 million people each year and it is estimated that there are 1 billion infected with TB worldwide. Due to this problem fluoroquinolones have attracted much attention as the new class of anti TB drugs due to their fewer toxic side effects, improved pharmacokinetic properties and extensive and potent activity against Grampositive and Gram-negative bacteria, including resistant strains. In this present review we report fluoroquinolones as a promising new class of anti TB.
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Cite this article as:
De Souza V. N. Marcus, Vasconcelos R. A. Thatyana, Almeida V. d. Mauro and Cardoso H. Silvia, Fluoroquinolones: An Important Class of Antibiotics Against Tuberculosis, Current Medicinal Chemistry 2006; 13 (4) . https://dx.doi.org/10.2174/092986706775527965
DOI https://dx.doi.org/10.2174/092986706775527965 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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