Abstract
During biological nitrogen fixation, the nitrogenase Fe-protein containing the [4Fe-4S] metal cluster has been shown to function in electron transfer to the MoFe-protein. This function of the Fe-protein is dependent on its conformational state and the metal cluster of the active site. This review will summarize the structures of the nucleotide bound (or "off") and amino-acid-substituted Fe-protein as well as the properties of the metal cluster in Fe-protein. The conformational changes in the nucleotide-dependent switch regions increase the driving force, leading to intermolecular electron transfer and macromolecular complex formation from the [4Fe-4S] metal cluster of the Fe-protein to the substrate reduction site of the MoFe-protein.
Keywords: Fe-protein, [FeS] metal cluster, Nucleotide, Conformational changes, Signal transduction, Electron transfer
Current Nanoscience
Title: Electron Transfer and Nano-Scale Motions in Nitrogenase Fe-Protein
Volume: 2 Issue: 1
Author(s): Mi Suk Jeong and Se Bok Jang
Affiliation:
Keywords: Fe-protein, [FeS] metal cluster, Nucleotide, Conformational changes, Signal transduction, Electron transfer
Abstract: During biological nitrogen fixation, the nitrogenase Fe-protein containing the [4Fe-4S] metal cluster has been shown to function in electron transfer to the MoFe-protein. This function of the Fe-protein is dependent on its conformational state and the metal cluster of the active site. This review will summarize the structures of the nucleotide bound (or "off") and amino-acid-substituted Fe-protein as well as the properties of the metal cluster in Fe-protein. The conformational changes in the nucleotide-dependent switch regions increase the driving force, leading to intermolecular electron transfer and macromolecular complex formation from the [4Fe-4S] metal cluster of the Fe-protein to the substrate reduction site of the MoFe-protein.
Export Options
About this article
Cite this article as:
Mi Suk Jeong and Se Bok Jang , Electron Transfer and Nano-Scale Motions in Nitrogenase Fe-Protein, Current Nanoscience 2006; 2 (1) . https://dx.doi.org/10.2174/157341306775473773
DOI https://dx.doi.org/10.2174/157341306775473773 |
Print ISSN 1573-4137 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6786 |
Call for Papers in Thematic Issues
Role of nanomaterials in fabrication of coatings, Machining and Joining
The application of nanoscience has brought about a revolution in the field of mechanical engineering by providing novel materials, boosting manufacturing processes, and generating cutting-edge products. The purpose of this special issue is to investigate the enormous impact that nanoscience has had on mechanical engineering, with a particular emphasis on ...read more
Advanced Inorganic Nanocomposites and Their Emerging Applications
This special issue collection will highlight developments on the recent trends about the synthesis of metal oxides, nanoclusters, biomaterials, 2D nanomaterials, nanocrystals, nanocomposites, etc. and their applications in electrochemical systems, tissue regeneration, energy storage and harvesting, sensors, etc. The novelty of the methods in the chemical synthesis and their characterizations, ...read more
Applicability of Nanotechnology for Performance Enhancement of Clean Energy Technologies
Population growth, industrialization, and improvement in living quality would lead to further increase in energy demand in near future. Regarding the disadvantages of fossil fuels such as fluctuations in their price, high emissions of greenhouse gases and restriction of their sources, it is crucial to use and exploit alternative energy ...read more
Graphene and 2D Materials for Energy Storage and Conversion
This thematic issue will discuss the recent advances in graphene-based nanomaterials for different energy technologies. Graphene possesses a high surface area, and stable structure and exhibits many interesting electronic, optical, and mechanical properties due to its 2D crystal structure. Graphene is of both fundamental interest and suitable for a wide ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers