Sulfated Tin Oxide: A Convenient Heterogeneous Catalyst for the Synthesis of 4-Arylmethylidene-3-Substituted-Isoxazol-5(4H)-Ones

Title:Sulfated Tin Oxide: A Convenient Heterogeneous Catalyst for the Synthesis of 4-Arylmethylidene-3-Substituted-Isoxazol-5(4H)-Ones

Volume: 18 Issue: 12

Author(s): Nitishkumar S. Kaminwar, Sunil U. Tekale, Srinivas L. Nakkalwar and Rajendra P. Pawar*

Affiliation:

• Department of Chemistry, Shiv Chhatrapati College, Cidco, Aurangabad, Maharashtra,India

Keywords: Isoxazol-5(4H)-one, STO, aldehyde, β-keto ester, hydroxylamine hydrochloride, heterogeneous catalyst.

Abstract: Synthesis of isoxazole structural heterocyclic compounds is important due to their wide range of biological activities. In the present article, we report a convenient and easy method for the synthesis of 4-arylmethylidene-3-substituted-isoxazol-5(4H)-ones by the one-pot three-component reaction of aldehydes, β-keto ester, and hydroxylamine hydrochloride catalyzed by sulfated tin oxide as a heterogeneous catalyst.

Cite this article as:

Kaminwar S. Nitishkumar, Tekale U. Sunil, Nakkalwar L. Srinivas and Pawar P. Rajendra *, Sulfated Tin Oxide: A Convenient Heterogeneous Catalyst for the Synthesis of 4-Arylmethylidene-3-Substituted-Isoxazol-5(4H)-Ones, Letters in Organic Chemistry 2021; 18 (12) . https://dx.doi.org/10.2174/1570178618666210729114845